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Information on EC 2.3.1.246 - 3,5-dihydroxyphenylacetyl-CoA synthase

for references in articles please use BRENDA:EC2.3.1.246

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IUBMB Comments

The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin.

The enzyme appears in viruses and cellular organisms

Synonyms
dpgA, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4 malonyl-CoA = (3,5-dihydroxyphenylacetyl)-CoA + 3 CoA + 4 CO2 + H2O
show the reaction diagram
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