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Information on EC 2.3.1.220 - 2,4,6-trihydroxybenzophenone synthase

for references in articles please use BRENDA:EC2.3.1.220

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IUBMB Comments

Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC 2.3.1.151, 2,3',4,6-tetrahydroxybenzophenone synthase).

The enzyme appears in viruses and cellular organisms
  • 2.3.1.220
  • falciparum
  • plasmodium
  • merozoite
  • malaria
  • subunit-based
  • erythrocyte
  • aotus
  • high-activity
  • receptor-ligand
  • sporozoite
  • anti-malarial
  • multi-stage
  • protection-inducing
  • multiepitope
  • hyaluronan
  • enzyme-treated
  • multi-antigenic
  • hyaluronan-binding
  • rhoptries
  • microneme
  • chemically-synthesized
  • rhoptry-associated
  • parasitophorous

Synonyms
habps, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + benzoyl-CoA = 4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
-
-, -
Highest Expressing Human Cell Lines
Cell Line Links Gene Links