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Information on EC 2.3.1.206 - 3,5,7-trioxododecanoyl-CoA synthase

for references in articles please use BRENDA:EC2.3.1.206

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IUBMB Comments

A polyketide synthase catalysing the first committed step in the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme was previously thought to also function as a cyclase, but the cyclization is now known to be catalysed by EC 4.4.1.26, olivetolic acid cyclase.

The expected taxonomic range for this enzyme is: Cannabis sativa

Synonyms
type iii pks, type iii polyketide synthase, olivetol synthase, tetraketide synthase, ola synthase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + hexanoyl-CoA = 3 CoA + 3,5,7-trioxododecanoyl-CoA + 3 CO2
show the reaction diagram
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