Information on EC 2.3.1.177 - 3,5-dihydroxybiphenyl synthase

for references in articles please use BRENDA:EC2.3.1.177
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IUBMB Comments
A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. EC 2.3.1.208, 4-hydroxycoumarin synthase) . This enzyme uses the same starter substrate as EC 2.3.1.151, benzophenone synthase.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
biphenyl synthase, BIS, BIS1, BIS1 biphenyl synthase, BIS2, BIS3, BIS3 biphenyl synthase, BIS4, MdBIS1, MdBIS3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2
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PATHWAY SOURCE
PATHWAYS
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