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Information on EC 2.3.1.164 - isopenicillin-N N-acyltransferase

for references in articles please use BRENDA:EC2.3.1.164

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IUBMB Comments

Proceeds by a two stage mechanism via 6-aminopenicillanic acid. Different from EC 3.5.1.11, penicillin amidase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
isopenicillin n acyltransferase, 6-aminopenicillanic acid acyltransferase, acyl coenzyme a:6-aminopenicillanic acid acyltransferase, acyl-coa:6-apa acyltransferase, ipn acyltransferase, acyl-coenzyme a:isopenicillin n acyltransferase, isopenicillin-n n-acyltransferase, acyl-coa:isopenicillin n acyltransferase, isopenicillin n:acyl-coa acyltransferase, isopenicillin n:acyl coa acyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate
show the reaction diagram
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