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Information on EC 2.3.1.149 - Platelet-activating factor acetyltransferase

for references in articles please use BRENDA:EC2.3.1.149

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IUBMB Comments

catalyses the transfer of the acetyl group from 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) to the sn-2 position of lyso-glycerophospholipids containing ethanolamine, choline, serine, inositol or phosphate groups at the sn-3 position as well as to sphingosine and long-chain fatty alcohols. The organyl group can be alkyl, acyl or alk-1-enyl (sometimes also collectively referred to as 'radyl').

The enzyme appears in viruses and cellular organisms

Synonyms
paf-ah, platelet-activating factor-acetylhydrolase, paf acetyltransferase, platelet-activating factor acetyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phospholipid = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-organyl-2-acetyl-sn-glycero-3-phospholipid
show the reaction diagram
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