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IUBMB CommentsCaffeoyl-CoA, feruloyl-CoA and sinapoyl-CoA can also act as donors, but more slowly.
The taxonomic range for the selected organisms is: Nicotiana tabacum
The enzyme appears in selected viruses and cellular organisms
Synonyms
hydroxycinnamoyltransferase, shikimate o-hydroxycinnamoyltransferase, hydroxycinnamoyl-coa:shikimate hydroxycinnamoyltransferase, hydroxycinnamoyl-coa shikimate/quinate hydroxycinnamoyltransferase, hct1806, hydroxycinnamoyl-coa:shikimate hydroxycinnamoyl transferase, oshct4, hct4918, hydroxycinnamoyl-coa:quinate hydroxycinnamoyltransferase, hydroxycinnamoyl-coa:shikimate/quinate hydroxycinnamoyltransferase,
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hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase
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hydroxycinnamoyl-CoA:shikimate O-hydroxycinnamoyl transferase
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hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyltransferase
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hydroxycinnamoyltransferase, shikimate
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p-coumaroyl-CoA:shikimic acid p-coumaroyl transferase
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p-hydroxycinnamoyl-CoA:shikimate-p-hydroxycinnamoyl transferase
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shikimate hydroxycinnamoyltransferase
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Acyl group transfer
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4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase
Caffeoyl-CoA, feruloyl-CoA and sinapoyl-CoA can also act as donors, but more slowly.
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4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
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r
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
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r
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
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r
additional information
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4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
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4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step
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additional information
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no substrate: anthranilate, glucose, malate, tyramine, spermidine, spermine, putrescine, agmatine, benzyl alcohol
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additional information
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no substrate: anthranilate, glucose, malate, tyramine, spermidine, spermine, putrescine, agmatine, benzyl alcohol
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4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step
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SwissProt
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HST_TOBAC
435
0
48265
Swiss-Prot
other Location (Reliability: 3)
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expression in Escherichia coli
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Hoffmann, L.; Maury, S.; Martz, F.; Geoffroy, P.; Legrand, M.
Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism
J. Biol. Chem.
278
95-103
2003
Nicotiana tabacum (Q8GSM7), Nicotiana tabacum
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