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Information on EC 2.1.3.10 - malonyl-S-ACP:biotin-protein carboxyltransferase

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IUBMB Comments
Derived from the components MadC and MadD of the anaerobic bacterium Malonomonas rubra, this enzyme is a component of EC 4.1.1.89, biotin-dependent malonate decarboxylase. The carboxy group is transferred from malonate to the prosthetic group of the biotin protein (MadF) with retention of configuration . Similar to EC 4.1.1.87, malonyl-S-ACP decarboxylase, which forms part of the biotin-independent malonate decarboxylase (EC 4.1.1.88), this enzyme also follows on from EC 2.3.1.187, acetyl-S-ACP:malonate ACP transferase, and results in the regeneration of the acetyl-[acyl-carrier protein] .
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Word Map
The expected taxonomic range for this enzyme is: Malonomonas rubra
Synonyms
acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase, MadC,D, malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase, malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a malonyl-[acyl-carrier protein] + a biotinyl-[protein] = an acetyl-[acyl-carrier protein] + a carboxybiotinyl-[protein]
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PATHWAY SOURCE
PATHWAYS
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