We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.
The enzyme appears in viruses and cellular organisms
Synonyms 3-hydroxyanthranilate 4-methyltransferase, more
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-hydroxyanthranilate 4-methyltransferase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
methyl group transfer
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase
Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
S-adenosyl-L-methionine + 3-hydroxyanthranilic acid
S-adenosyl-L-homocysteine + 4-methyl-3-hydroxyanthranilic acid
additional information
?
-
-
Substrates: does not catalyze the methylation of 3-hydroxy-DL-kynurenine Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: involved in the biosynthesis of the antibiotic actinomycin Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: - Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: - Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilic acid
S-adenosyl-L-homocysteine + 4-methyl-3-hydroxyanthranilic acid
-
Substrates: - Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilic acid
S-adenosyl-L-homocysteine + 4-methyl-3-hydroxyanthranilic acid
-
Substrates: - Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilic acid
S-adenosyl-L-homocysteine + 4-methyl-3-hydroxyanthranilic acid
-
Substrates: - Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: involved in the biosynthesis of the antibiotic actinomycin Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: - Products: -
?
S-adenosyl-L-methionine + 3-hydroxyanthranilate
S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
-
Substrates: - Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.64
3-Hydroxyanthranilate
-
-
0.18
S-adenosyl-L-methionine
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6 - 7
-
sodium phosphate buffer
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
intracellular membrane associated
brenda
Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
36000
-
1 * 36000, SDS-PAGE
37000
-
gel filtration, chromatography in 0.5 M NaCl
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
monomer
-
1 * 36000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-70°C, 5% glycerol, 50 mM sodium phosphate, pH 7.0, 10 mM Na2EDTA, 5 mM 2-mercaptoethanol, 1 mM phenylmethylsulfonyl fluoride, quite stable, can be frozen and thawed several times without appreciable loss of activity
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
gene for the 88000 Mr PHS subunit cloned
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Jones, G.H.
Actinomycin synthesis in Streptomyces antibioticus: Enzymatic conversion of 3-hydroxyanthranilic acid to 4-methyl-3-hydroxyanthranilic acid
J. Bacteriol.
169
5575-5578
1987
Streptomyces antibioticus, Streptomyces anulatus, Streptomyces sp.
brenda
Fawaz, F.; Jones, G.H.
Actinomycin synthesis in Streptomyces antibioticus
J. Biol. Chem.
263
4602-4606
1988
Streptomyces antibioticus
brenda
html completed