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Information on EC - tetrahydromethanopterin S-methyltransferase

for references in articles please use BRENDA:EC2.1.1.86
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IUBMB Comments
Involved in the formation of methane from CO2 in methanogenic archaea. The reaction involves the export of one or two sodium ions. The enzyme from the archaeon Methanobacterium thermoautotrophicum is a membrane-associated multienzyme complex composed of eight different subunits, and contains a 5'-hydroxybenzimidazolyl-cobamide prosthetic group, to which the methyl group is attached during the transfer. A soluble enzyme that is induced by the presence of CO has been reported as well .
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
h4mpt, n5-methyltetrahydromethanopterin:coenzyme m methyltransferase, ma4384, mtra-h, tetrahydromethanopterin s-methyltransferase, mtra-h complex, tetrahydromethanopterin methyltransferase, methyl-tetrahydromethanopterin:coenzyme-m methyltransferase, n5-methyltetrahydromethanopterin coenzyme m methyltransferase, more
5-methyl-5,6,7,8-tetrahydromethanopterin + CoM + 2 Na+/in = 5,6,7,8-tetrahydromethanopterin + 2-(methylsulfanyl)ethane-1-sulfonate + 2 Na+/out
show the reaction diagram
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