Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.1.1.57 - methyltransferase cap1 and Organism(s) Dengue virus type 2 and UniProt Accession P12823

for references in articles please use BRENDA:EC2.1.1.57
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.57 methyltransferase cap1
IUBMB Comments
This enzyme catalyses the methylation of the ribose on the first transcribed nucleotide of mRNA or snRNA molecules. This methylation event is known as cap1, and occurs in all mRNAs and snRNAs of higher eukaryotes, including insects, vertebrates and their viruses. The human enzyme can also methylate mRNA molecules that lack methylation on the capping 5'-triphosphoguanosine .
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Dengue virus type 2
UNIPROT: P12823
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a 5'-(N7-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA]
=
+
a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Synonyms
nsp16, 2'-o-methyltransferase, 2'-o-mtase, cmtr1, ns5 mtase, 2'-o mtase, (nucleoside-2'-o-)-methyltransferase, nonstructural protein 16, 2'-o methyltransferase, isg95, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
messenger ribonucleate nucleoside 2'-methyltransferase
-
-
-
-
messenger RNA (nucleoside-2'-)-methyltransferase
-
-
-
-
methyltransferase, messenger ribonucleate nucleoside 2'-
-
-
-
-
mRNA (nucleoside-2'-O)-methyltransferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
methyl group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(ribonucleotide)-[mRNA] 2-O-methyltransferase
This enzyme catalyses the methylation of the ribose on the first transcribed nucleotide of mRNA or snRNA molecules. This methylation event is known as cap1, and occurs in all mRNAs and snRNAs of higher eukaryotes, including insects, vertebrates and their viruses. The human enzyme can also methylate mRNA molecules that lack methylation on the capping 5'-triphosphoguanosine [6].
CAS REGISTRY NUMBER
COMMENTARY hide
61970-02-3
-