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BRENDA support

Information on EC 2.1.1.49 - amine N-methyltransferase

for references in articles please use BRENDA:EC2.1.1.49

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IUBMB Comments

An enzyme of very broad specificity; many primary, secondary and tertiary amines can act as acceptors, including tryptamine, aniline, nicotine and a variety of drugs and other xenobiotics.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
arylamine n-methyltransferase, amine n-methyltransferase, nicotine n-methyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links