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Information on EC 2.1.1.41 - sterol 24-C-methyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9LM02

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.41 sterol 24-C-methyltransferase
IUBMB Comments
Requires glutathione. Acts on a range of sterols with a 24(25)-double bond in the sidechain. While zymosterol is the preferred substrate it also acts on desmosterol, 5alpha-cholesta-7,24-dien-3beta-ol, 5alpha-cholesta-5,7,24-trien-3beta-ol, 4alpha-methylzymosterol and others. S-Adenosyl-L-methionine attacks the Si-face of the 24(25) double bond and the C-24 hydrogen is transferred to C-25 on the Re face of the double bond.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9LM02
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
erg6p, sterol 24-c-methyltransferase, c-24 sterol methyltransferase, tbsmt, pbsmt, c24-methyltransferase, 24-c-sterol methyltransferase, (s)-adenosyl-l-methionine:delta24(25)-sterol methyl transferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
24-sterol C-methyltransferase
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DELTA24-methyltransferase
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DELTA24-sterol methyltransferase
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methyltransferase, DELTA24-sterol
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phytosterol methyltransferase
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S-adenosyl-4-methionine:sterol DELTA24-methyltransferase
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S-adenosyl-L-methionine:DELTA24(23)-sterol methyltransferase
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SMT1
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zymosterol-24-methyltransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
methyl group transfer
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PATHWAY SOURCE
PATHWAYS
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-, -, -
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase
Requires glutathione. Acts on a range of sterols with a 24(25)-double bond in the sidechain. While zymosterol is the preferred substrate it also acts on desmosterol, 5alpha-cholesta-7,24-dien-3beta-ol, 5alpha-cholesta-5,7,24-trien-3beta-ol, 4alpha-methylzymosterol and others. S-Adenosyl-L-methionine attacks the Si-face of the 24(25) double bond and the C-24 hydrogen is transferred to C-25 on the Re face of the double bond.
CAS REGISTRY NUMBER
COMMENTARY hide
37257-07-1
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SMT1_ARATH
336
0
38268
Swiss-Prot
other Location (Reliability: 2)