Information on EC - glycine betaine-corrinoid protein Co-methyltransferase

for references in articles please use BRENDA:EC2.1.1.376
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EC Tree
IUBMB Comments
The enzyme, which catalyses the transfer of a methyl group from glycine betaine to a glycine betaine-specific corrinoid protein (MtgC), is involved in methanogenesis from glycine betaine in some methanogenic archaea, and in glycine betaine degradation in some bacteria. Unlike similar enzymes involved in methanogenesis from methylated C1 compounds, this enzyme does not contain the unusual amino acid L-pyrrolysine.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
a [Co(I) glycine betaine-specific corrinoid protein]
a [methyl-Co(III) glycine betaine-specific corrinoid protein]
dsy3156, gb methyltransferase, glycine betaine:corrinoid methyltransferase, more
glycine betaine + a [Co(I) glycine betaine-specific corrinoid protein] = N,N-dimethylglycine + a [methyl-Co(III) glycine betaine-specific corrinoid protein]
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