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Information on EC 2.1.1.358 - [histone H3]-dimethyl-L-lysine36 N-methyltransferase

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IUBMB Comments
The enzyme, found in metazoa, methylates a dimethylated L-lysine36 residue of histone H3 (H3K36), which has been methylated previously by EC 2.1.1.357, [histone H3]-lysine36 N-dimethyltransferase. The homologous enzyme from yeast catalyses all three methylations (see EC 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase).
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The enzyme appears in viruses and cellular organisms
Synonyms
H3K36 HMT, H3K36 methyltransferase, histone H3 lysine 36 methyltransferase, HYPB, KMT3A, SETD2, more
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