Reference on EC 2.1.1.357 - [histone H3]-lysine36 N-dimethyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Eram, M.S.; Kuznetsova, E.; Li, F.; Lima-Fernandes, E.; Kennedy, S.; Chau, I.; Arrowsmith, C.H.; Schapira, M.; Vedadi, M.
Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2
Biochim. Biophys. Acta
1850
1842-1848
2015
Homo sapiens (Q9NR48)
Rogawski, D.; Grembecka, J.; Cierpicki, T.
H3K36 methyltransferases as cancer drug targets Rationale and perspectives for inhibitor development
Future Med. Chem.
8
1589-1607
2016
Homo sapiens, Homo sapiens (Q96L73), Homo sapiens (Q9NR48)
-
Poulin, M.; Schneck, J.; Matico, R.; Hou, W.; McDevitt, P.; Holbert, M.; Schramm, V.
Nucleosome binding alters the substrate bonding environment of histone H3 lysine 36 methyltransferase NSD2
J. Am. Chem. Soc.
138
6699-6702
2016
Homo sapiens (Q96028)
Qiao, Q.; Li, Y.; Chen, Z.; Wang, M.; Reinberg, D.; Xu, R.
The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation
J. Biol. Chem.
286
8361-8368
2011
Homo sapiens (Q96L73)
Zhou, X.; Zhu, R.; Wu, X.; Xu, H.; Li, Y.; Xu, Q.; Liu, S.; Huang, H.; Xu, X.; Wan, L.; Wu, Q.; Liu, J.
NSD2 promotes ventricular remodelling mediated by the regulation of H3K36me2
J. Cell. Mol. Med.
23
568-575
2019
Mus musculus (Q8BVE8)
Wagner, E.; Carpenter, P.
Understanding the language of Lys36 methylation at histone H3
Nat. Rev. Mol. Cell Biol.
13
115-126
2012
Homo sapiens
Miyazaki, H.; Higashimoto, K.; Yada, Y.; Endo, T.A.; Sharif, J.; Komori, T.; Matsuda, M.; Koseki, Y.; Nakayama, M.; Soejima, H.; Handa, H.; Koseki, H.; Hirose, S.; Nishioka, K.
Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing
PLoS Genet.
9
e1003897
2013
Mus musculus (Q99MY8)
Fnu, S.; Williamson, E.; De Haro, L.; Brenneman, M.; Wray, J.; Shaheen, M.; Radhakrishnan, K.; Lee, S.; Nickoloff, J.; Hromasa, R.
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
Proc. Natl. Acad. Sci. USA
108
551-556
2011
Homo sapiens (Q53H47), Homo sapiens
Poulin, M.; Schneck, J.; Matico, R.; McDevitt, P.; Huddleston, M.; Hou, W.; Johnson, N.; Thrall, S.; Meek, T.; Schramm, V.
Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36
Proc. Natl. Acad. Sci. USA
113
1197-1201
2016
Homo sapiens (O96028)
Fang, D.; Gan, H.; Lee, J.; Han, J.; Wang, Z.; Riester, S.; Jin, L.; Chen, J.; Zhou, H.; Wang, J.; Zhang, H.; Yang, N.; Bradley, E.; Ho, T.; Rubin, B.; Bridge, J.; Thibodeau, S.; Ordog, T.; Chen, Y.; Van Wijnen, A.; Oliveira, A.; Xu, R.; Westendorf, J.
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
Science
352
1344-1348
2016
Homo sapiens
Morishita, M.; Di Luccio, E.
Structural insights into the regulation and the recognition of histone marks by the SET domain of NSD1
Biochem. Biophys. Res. Commun.
412
214-219
2011
Homo sapiens (Q96L73)
Morishita, M.; Mevius, D.; Di Luccio, E.
In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L
BMC Struct. Biol.
14
25
2014
Homo sapiens (Q96L73)
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