Reference on EC 2.1.1.354 - [histone H3]-lysine4 N-trimethyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Yeates, T.O.
Structures of SET domain proteins: protein lysine methyltransferases make their mark
Cell
111
5-7
2002
Homo sapiens
Lee, J.H.; Skalnik, D.G.
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex
J. Biol. Chem.
280
41725-41731
2005
Mus musculus, Homo sapiens (O15047), Homo sapiens
Raman, S.B.; Nguyen, M.H.; Zhang, Z.; Cheng, S.; Jia, H.Y.; Weisner, N.; Iczkowski, K.; Clancy, C.J.
Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis
Mol. Microbiol.
60
697-709
2006
Saccharomyces cerevisiae, Candida albicans, Candida albicans CAI12
Kim, T.; Buratowski, S.
Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions
Cell
137
259-272
2009
Saccharomyces cerevisiae
Wu, X.; Hua, X.
Menin, histone H3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective
Curr. Mol. Med.
8
805-815
2008
Drosophila melanogaster, Homo sapiens
Butler, J.S.; Lee, J.H.; Skalnik, D.G.
CFP1 interacts with DNMT1 independently of association with the Setd1 histone H3K4 methyltransferase complexes
DNA Cell Biol.
27
533-543
2008
Homo sapiens
Halbach, A.; Zhang, H.; Wengi, A.; Jablonska, Z.; Gruber, I.M.; Halbeisen, R.E.; Dehe, P.M.; Kemmeren, P.; Holstege, F.; Geli, V.; Gerber, A.P.; Dichtl, B.
Cotranslational assembly of the yeast SET1C histone methyltransferase complex
EMBO J.
28
2959-2970
2009
Saccharomyces cerevisiae
Xu, Z.; Gong, Q.; Xia, B.; Groves, B.; Zimmermann, M.; Mugler, C.; Mu, D.; Matsumoto, B.; Seaman, M.; Ma, D.
A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking
J. Cell Biol.
186
343-353
2009
Rattus norvegicus
Kim, D.H.; Lee, J.; Lee, B.; Lee, J.W.
ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity
Mol. Endocrinol.
23
1556-1562
2009
Mus musculus
Lee, J.; Kim, D.H.; Lee, S.; Yang, Q.H.; Lee, D.K.; Lee, S.K.; Roeder, R.G.; Lee, J.W.
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
Proc. Natl. Acad. Sci. USA
106
8513-8518
2009
Mus musculus
Mihola, O.; Trachtulec, Z.; Vlcek, C.; Schimenti, J.; Forejt, J.
A mouse speciation gene encodes a meiotic histone H3 methyltransferase
Science
323
373-375
2009
Mus musculus (C4MLH8), Mus musculus
Ardehali, M.B.; Mei, A.; Zobeck, K.L.; Caron, M.; Lis, J.T.; Kusch, T.
Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription
EMBO J.
30
2817-2828
2011
Drosophila melanogaster
Hallson, G.; Hollebakken, R.E.; Li, T.; Syrzycka, M.; Kim, I.; Cotsworth, S.; Fitzpatrick, K.A.; Sinclair, D.A.; Honda, B.M.
dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development
Genetics
190
91-100
2012
Drosophila melanogaster
Mersman, D.P.; Du, H.N.; Fingerman, I.M.; South, P.F.; Briggs, S.D.
Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression
J. Biol. Chem.
287
2652-2665
2012
Saccharomyces cerevisiae
Valencia-Morales, M.D.; Camas-Reyes, J.A.; Cabrera-Ponce, J.L.; Alvarez-Venegas, R.
The Arabidopsis thaliana SET-domain-containing protein ASHH1/SDG26 interacts with itself and with distinct histone lysine methyltransferases
J. Plant Res.
125
679-692
2012
Arabidopsis thaliana
Cho, Y.W.; Hong, S.; Ge, K.
Affinity purification of MLL3/MLL4 histone H3K4 methyltransferase complex
Methods Mol. Biol.
809
465-472
2012
Homo sapiens
Raduwan, H.; Isola, A.L.; Belden, W.J.
Methylation of histone H3 on lysine 4 by the lysine methyltransferase SET1 protein is needed for normal clock gene expression
J. Biol. Chem.
288
8380-8390
2013
Neurospora crassa
Kim, J.D.; Kim, E.; Koun, S.; Ham, H.J.; Rhee, M.; Kim, M.J.; Huh, T.L.
Proper activity of histone H3 lysine 4 (H3K4) methyltransferase is required for morphogenesis during zebrafish cardiogenesis
Mol. Cells
38
580-586
2015
Danio rerio (Q6DHG0), Danio rerio
Ortega-Molina, A.; Boss, I.W.; Canela, A.; Pan, H.; Jiang, Y.; Zhao, C.; Jiang, M.; Hu, D.; Agirre, X.; Niesvizky, I.; Lee, J.E.; Chen, H.T.; Ennishi, D.; Scott, D.W.; Mottok, A.; Hother, C.; Liu, S.; Cao, X.J.; Tam, W.; Shaknovich, R.; Garcia, B.A.; Gascoyne, R.D.; Ge, K.; Shilatifard, A.; Elemento, O.; Nussenzweig, A.; Melnick, A.M.; Wendel, H.G.
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Nat. Med.
21
1199-1208
2015
Mus musculus (Q6PDK2)
Kusch, T.; Mei, A.; Nguyen, C.
Histone H3 lysine 4 trimethylation regulates cotranscriptional H2A variant exchange by Tip60 complexes to maximize gene expression
Proc. Natl. Acad. Sci. USA
111
4850-4855
2014
Drosophila melanogaster
Yang, W.; Ernst, P.
Distinct functions of H3K4 methyltransferases in normal and malignant hematopoiesis
Curr. Opin. Hematol.
24
322-328
2017
Mus musculus
Schibler, A.; Koutelou, E.; Tomida, J.; Wilson-Pham, M.; Wang, L.; Lu, Y.; Cabrera, A.P.; Chosed, R.J.; Li, W.; Li, B.; Shi, X.; Wood, R.D.; Dent, S.Y.
Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2
Genes Dev.
30
1187-1197
2016
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Blazer, L.L.; Lima-Fernandes, E.; Gibson, E.; Eram, M.S.; Loppnau, P.; Arrowsmith, C.H.; Schapira, M.; Vedadi, M.
PR domain-containing protein 7 (PRDM7) is a histone 3 lysine 4 trimethyltransferase
J. Biol. Chem.
291
13509-13519
2016
Homo sapiens (Q9NQW5)
Soares, L.M.; He, P.C.; Chun, Y.; Suh, H.; Kim, T.; Buratowski, S.
Determinants of histone H3K4 methylation patterns
Mol. Cell
68
773-785.e6
2017
Saccharomyces cerevisiae
Dhar, S.S.; Zhao, D.; Lin, T.; Gu, B.; Pal, K.; Wu, S.J.; Alam, H.; Lv, J.; Yun, K.; Gopalakrishnan, V.; Flores, E.R.; Northcott, P.A.; Rajaram, V.; Li, W.; Shilatifard, A.; Sillitoe, R.V.; Chen, K.; Lee, M.G.
MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes
Mol. Cell
70
825-841.e6
2018
Mus musculus (Q6PDK2)
Han, S.; Schroeder, E.A.; Silva-Garcia, C.G.; Hebestreit, K.; Mair, W.B.; Brunet, A.
Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan
Nature
544
185-190
2017
Caenorhabditis elegans
Liu, K.; Yu, Y.; Dong, A.; Shen, W.H.
SET DOMAIN GROUP701 encodes a H3K4-methytransferase and regulates multiple key processes of rice plant development
New Phytol.
215
609-623
2017
Oryza sativa
html completed