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BRENDA support

Information on EC 2.1.1.330 - 5'-demethylyatein 5'-O-methyltransferase

for references in articles please use BRENDA:EC2.1.1.330

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IUBMB Comments

The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs.

The expected taxonomic range for this enzyme is: Sinopodophyllum hexandrum

Synonyms
OMT1, Phex13114, S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinol C-methyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + (-)-5'-demethylyatein = S-adenosyl-L-homocysteine + (-)-yatein
show the reaction diagram
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Highest Expressing Human Cell Lines
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