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Reference on EC 2.1.1.314 - diphthine methyl ester synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moehring, J.M.; Moehring, T.J.
The post-translational trimethylation of diphthamide studied in vitro
J. Biol. Chem.
263
3840-3844
1988
Saccharomyces cerevisiae, Cricetulus griseus
Manually annotated by BRENDA team
Chen, J.Y.C.; Bodley, J.W.
Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase
J. Biol. Chem.
263
11692-11696
1988
Saccharomyces cerevisiae (P32469), Saccharomyces cerevisiae ATCC 204508 (P32469)
Manually annotated by BRENDA team
Lin, Z.; Su, X.; Chen, W.; Ci, B.; Zhang, S.; Lin, H.
Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis
J. Am. Chem. Soc.
136
6179-6182
2014
Saccharomyces cerevisiae (P32469), Saccharomyces cerevisiae ATCC 204508 (P32469)
Manually annotated by BRENDA team
Tsuda-Sakurai, K.; Kimura, M.; Miura, M.
Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras
Genes Cells
25
76-85
2020
Drosophila sp. (in: flies)
Manually annotated by BRENDA team
Hoerberg, J.; Saenz-Mendez, P.; Eriksson, L.A.
QM/MM studies of Dph5 - a promiscuous methyltransferase in the eukaryotic biosynthetic pathway of diphthamide
J. Chem. Inf. Model.
58
1406-1414
2018
Saccharomyces cerevisiae (P32469)
Manually annotated by BRENDA team
Schaffrath, R.; Abdel-Fattah, W.; Klassen, R.; Stark, M.
The diphthamide modification pathway from Saccharomyces cerevisiae - revisited
Mol. Microbiol.
94
1213-1226
2016
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Hawer, H.; tkr, K.; Arend, M.; Mayer, K.; Adrian, L.; Brinkmann, U.; Schaffrath, R.
Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
PLoS ONE
13
e0205870
2018
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Stahl, S.; Da Silva Mateus Seidl, A.; Ducret, A.; Van Geijtenbeek, S.; Michel, S.; Racek, T.; Birzele, F.; Haas, A.; Rueger, R.; Gerg, M.; Niederfellner, G.; Pastan, I.; Brinkmann, U.
Loss of diphthamide pre-activates NF-kappaB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor
Proc. Natl. Acad. Sci. USA
112
10732-10737
2015
Homo sapiens (Q9H2P9)
Manually annotated by BRENDA team
Mayer, K.; Schrder, A.; Schnitger, J.; Stahl, S.; Brinkmann, U.
Influence of DPH1 and DPH5 protein variants on the synthesis of diphthamide, the target of ADPRibosylating toxins
Toxins
9
E78
2017
Homo sapiens (Q9H2P9)
Manually annotated by BRENDA team