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Information on EC 2.1.1.287 - 25S rRNA (adenine645-N1)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.287

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IUBMB Comments

The enzyme is found in eukaryotes. The adenine position refers to tRNA the yeast Saccharomyces cerevisiae, in which the enzyme is important for ribosome biogenesis.

The enzyme appears in viruses and cellular organisms
Reaction Schemes

Synonyms
ribosomal rna-processing protein 8, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + adenine645 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine645 in 25S rRNA
show the reaction diagram
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links