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BRENDA support

Information on EC 2.1.1.214 - tRNA (guanine10-N2)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.214

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IUBMB Comments

In contrast to the archaeal enzyme tRNA (guanine10-N2)-dimethyltransferase (EC 2.1.1.213), tRNA (guanine10-N2)-methyltransferase from yeast does not catalyse the methylation from N2-methylguanine10 to N2-dimethylguanine10 in tRNA.

The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Reaction Schemes

Synonyms
trm11, trna mtase, archaeal trm11, trm11p, trm11-trm112 complex, yol124c, eukaryotic trm11, n2,n2-dimethylguanosine trna methyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + guanine10 in tRNA = S-adenosyl-L-homocysteine + N2-methylguanine10 in tRNA
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
tRNA methylation (yeast)
Highest Expressing Human Cell Lines
Cell Line Links Gene Links