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BRENDA support

Information on EC 2.1.1.205 - tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.205

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IUBMB Comments

The enzyme from Saccharomyces cerevisiae catalyses the formation of 2′-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu.

The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
cytidine32/guanosine34 in tRNA
=
+
2'-O-methylcytidine32/2'-O-methylguanosine34 in tRNA

Synonyms
trm7p, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O-methylguanosine34 in tRNA
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
tRNA methylation (yeast)
Highest Expressing Human Cell Lines
Cell Line Links Gene Links