Information on EC 2.1.1.196 - cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]

for references in articles please use BRENDA:EC2.1.1.196
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IUBMB Comments
This enzyme, which participates in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyses both methylation at C-15 and decarboxylation of the C-12 acetate side chain of cobalt-precorrin-6B. The equivalent activity in the aerobic adenosylcobalamin biosynthesis pathway is catalysed by the bifunctional enzyme EC 2.1.1.132, precorrin-6B C5,15-methyltransferase (decarboxylating).
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
CbiE, CbiT, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cobalt-precorrin-6B + S-adenosyl-L-methionine = cobalt-precorrin-7 + S-adenosyl-L-homocysteine + CO2
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