The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA .
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The expected taxonomic range for this enzyme is: Escherichia coli
The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA [1].
the recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunit nor completely deproteinized 23 S rRNA
knockout of the ybiN gene leads to loss of modification at adenine1618. The modification is restored if ybiN knock-out strain has been co-transformed with a plasmid expressing the ybiN gene. Both lack of the ybiN gene and it's overexpression leads to growth retardation and loss of cell fitness comparative to the parental strain
Sergiev, P.; Serebryakova, M.; Bogdanov, A.; Dontsova, O.
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for Modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel
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2.1.1.181 23S rRNA (adenine1618-N6)-methyltransferase
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