Reference on EC 2.1.1.180 - 16S rRNA (adenine1408-N1)-methyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wachino, J.; Shibayama, K.; Kurokawa, H.; Kimura, K.; Yamane, K.; Suzuki, S.; Shibata, N.; Ike, Y.; Arakawa, Y.
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides
Antimicrob. Agents Chemother.
51
4401-4409
2007
Escherichia coli (A8C927), Escherichia coli
Koscinski, L.; Feder, M.; Bujnicki, J.M.
Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics
Cell Cycle
6
1268-1271
2007
Streptoalloteichus hindustanus (Q2MEY3)
Holmes, D.J.; Drocourt, D.; Tiraby, G.; Cundliffe, E.
Cloning of an aminoglycoside-resistance-encoding gene, kamC, from Saccharopolyspora hirsuta: comparison with kamB from Streptomyces tenebrarius
Gene
102
19-26
2007
Streptoalloteichus tenebrarius (P25920)
Beauclerk, A.A.; Cundliffe, E.
Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides
J. Mol. Biol.
193
661-671
1987
Streptomyces tenjimariensis
Macmaster, R.; Zelinskaya, N.; Savic, M.; Rankin, C.R.; Conn, G.L.
Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria
Nucleic Acids Res.
38
7791-7799
2010
Escherichia coli, Streptoalloteichus tenebrarius (A8G927)
Zelinskaya, N.; Witek, M.A.; Conn, G.L.
The pathogen-derived aminoglycoside resistance 16S rRNA methyltransferase NpmA possesses dual m1A1408/m1G1408 specificity
Antimicrob. Agents Chemother.
59
7862-7865
2015
Escherichia coli (A8C927)
Witek, M.A.; Conn, G.L.
Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: expression and functional characterization of four hypothetical enzymes of diverse bacterial origin
Biochim. Biophys. Acta
1844
1648-1655
2014
uncultured bacterium, Thermomonospora curvata, Catenulispora acidiphila, Candidatus Arthromitus sp. SFB-mouse, Catenulispora acidiphila DSM 44928, Thermomonospora curvata DSM 43183
Witek, M.A.; Conn, G.L.
Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization
Nucleic Acids Res.
44
342-353
2016
Catenulispora acidiphila
Dunkle, J.A.; Vinal, K.; Desai, P.M.; Zelinskaya, N.; Savic, M.; West, D.M.; Conn, G.L.; Dunham, C.M.
Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA
Proc. Natl. Acad. Sci. USA
111
6275-6280
2014
Escherichia coli (A8C927), Escherichia coli ARS3 (A8C927)
Savic, M.; Sunita, S.; Zelinskaya, N.; Desai, P.M.; Macmaster, R.; Vinal, K.; Conn, G.L.
30S Subunit-dependent activation of the Sorangium cellulosum So ce56 aminoglycoside resistance-conferring 16S rRNA methyltransferase Kmr
Antimicrob. Agents Chemother.
59
2807-2816
2015
Sorangium cellulosum (B2L3G9)
Vinal, K.; Conn, G.
Substrate recognition and modification by a pathogen-associated aminoglycoside resistance 16S rRNA methyltransferase
Antimicrob. Agents Chemother.
61
e00077
2017
Escherichia coli (A8C927)
Kanazawa, H.; Baba, F.; Koganei, M.; Kondo, J.
A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA
Nucleic Acids Res.
45
12529-12535
2017
Escherichia coli (A8C927)
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