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Information on EC 2.1.1.152 - precorrin-6A synthase (deacetylating)

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.152 precorrin-6A synthase (deacetylating)
IUBMB Comments
The enzyme, which participates in the aerobic (late cobalt insertion) cobalamin biosythesis pathway, catalyses two reactions -the methylation of carbon C1 of precorrin-5, and its deacetylation, forming precorrin-6A. See EC 2.1.1.195, cobalt-precorrin-5B (C1)-methyltransferase, for the C1-methyltransferase that participates in the anaerobic cobalamin biosynthesis pathway.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
CobF, precorrin-6X synthase (deacetylating), more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + precorrin-5 + H2O = S-adenosyl-L-homocysteine + precorrin-6A + acetate
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PATHWAY SOURCE
PATHWAYS
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