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Information on EC 2.1.1.14 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase

for references in articles please use BRENDA:EC2.1.1.14

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IUBMB Comments

Requires phosphate and contains zinc. The enzyme from Escherichia coli also requires a reducing system. Unlike EC 2.1.1.13, methionine synthase, this enzyme does not contain cobalamin.

The enzyme appears in viruses and cellular organisms

Synonyms
met-8, cobalamin-independent methionine synthase, cobalamin-independent methionine synthase (mete), methionine synthase mete, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase, ppmete, atmete, 5-methyltetrahydropteroyltriglutamate-homocysteine s-methyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-methionine biosynthesis I, L-methionine biosynthesis II, L-methionine biosynthesis III, S-adenosyl-L-methionine salvage I, S-adenosyl-L-methionine salvage II, seleno-amino acid biosynthesis (plants)