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Disease on EC 2.1.1.137 - arsenite methyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Atherosclerosis
Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the Mouse Model and the Role of As3mt-Mediated Methylation.
Ethnic, Geographic, and Genetic Differences in Arsenic Metabolism at Low Arsenic Exposure: A Preliminary Analysis in the Multi-Ethnic Study of Atherosclerosis (MESA).
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.
Carcinogenesis
Arsenic Methyltransferase and Methylation of Inorganic Arsenic.
Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies.
Inorganic arsenic-mediated upregulation of AS3MT promotes proliferation of nonsmall cell lung cancer cells by regulating cell cycle genes.
N6-Methyladenine DNA Modification in the Human Genome.
Role of the Met(287)Thr polymorphism in the AS3MT gene on the metabolic arsenic profile.
Carcinoma
Genetic variation in arsenic (+3 oxidation state) methyltransferase (AS3MT), arsenic metabolism and risk of basal cell carcinoma in a European population.
Carcinoma, Basal Cell
Genetic variation in arsenic (+3 oxidation state) methyltransferase (AS3MT), arsenic metabolism and risk of basal cell carcinoma in a European population.
Carcinoma, Hepatocellular
Manipulation of expression of arsenic (+3 oxidation state) methyltransferase in cultured cells.
shRNA silencing of AS3MT expression minimizes arsenic methylation capacity of HepG2 cells.
Carcinoma, Non-Small-Cell Lung
Inorganic arsenic-mediated upregulation of AS3MT promotes proliferation of nonsmall cell lung cancer cells by regulating cell cycle genes.
Cardiovascular Diseases
Low-level arsenic exposure, AS3MT gene polymorphism and cardiovascular diseases in rural Texas counties.
Carotid Artery Diseases
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.
Coronary Artery Disease
Association of N6AMT1 rs2254638 Polymorphism With Clopidogrel Response in Chinese Patients With Coronary Artery Disease.
Coronary Disease
Genomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of Clopidogrel.
Low-level arsenic exposure, AS3MT gene polymorphism and cardiovascular diseases in rural Texas counties.
Hydronephrosis
Effect of Sodium Arsenite Dose Administered in the Drinking Water on the Urinary Bladder Epithelium of Female Arsenic (+3 oxidation state) Methyltransferase Knockout Mice.
Hyperlipidemias
Low-level arsenic exposure, AS3MT gene polymorphism and cardiovascular diseases in rural Texas counties.
Hypertension
Low-level arsenic exposure, AS3MT gene polymorphism and cardiovascular diseases in rural Texas counties.
Insulin Resistance
Knockout of arsenic (+3 oxidation state) methyltransferase is associated with adverse metabolic phenotype in mice: the role of sex and arsenic exposure.
Leukemia
Biotransformation of arsenic trioxide by AS3MT favors eradication of acute promyelocytic leukemia: revealing the hidden facts.
Role of arsenic (+3 oxidation state) methyltransferase in arsenic mediated APL treatment: an in vitro investigation.
Leukemia, Promyelocytic, Acute
Biotransformation of arsenic trioxide by AS3MT favors eradication of acute promyelocytic leukemia: revealing the hidden facts.
Role of arsenic (+3 oxidation state) methyltransferase in arsenic mediated APL treatment: an in vitro investigation.
Lung Neoplasms
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.
Inorganic arsenic-mediated upregulation of AS3MT promotes proliferation of nonsmall cell lung cancer cells by regulating cell cycle genes.
Neoplasms
Arsenic Methyltransferase and Methylation of Inorganic Arsenic.
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.
Effects of Arsenic (+3 Oxidation State) Methyltransferase Gene Polymorphisms and Expression on Bladder Cancer: Evidence from a Systematic Review, Meta-analysis and TCGA Dataset.
Inorganic arsenic-mediated upregulation of AS3MT promotes proliferation of nonsmall cell lung cancer cells by regulating cell cycle genes.
N6-Methyladenine DNA Modification in the Human Genome.
Polymorphisms in arsenic metabolism genes, urinary arsenic methylation profile and cancer.
Neuroblastoma
Identification and characterisation of arsenite (+3 Oxidation State) methyltransferase (AS3MT) in mouse neuroblastoma cell line N1E-115.
Obesity
Knockout of arsenic (+3 oxidation state) methyltransferase is associated with adverse metabolic phenotype in mice: the role of sex and arsenic exposure.
Skin Neoplasms
Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study.
Urinary Bladder Neoplasms
Effects of Arsenic (+3 Oxidation State) Methyltransferase Gene Polymorphisms and Expression on Bladder Cancer: Evidence from a Systematic Review, Meta-analysis and TCGA Dataset.
Genetic variation in Glutathione S-Transferase Omega-1, Arsenic Methyltransferase and Methylene-tetrahydrofolate Reductase, arsenic exposure and bladder cancer: a case-control study.
Polymorphisms of Arsenic (+3 Oxidation State) Methyltransferase and Arsenic Methylation Capacity Affect the Risk of Bladder Cancer.
Vaccinia
Progress in genome-wide association studies of schizophrenia in Han Chinese populations.