Information on EC 2.1.1.131 - precorrin-3B C17-methyltransferase

for references in articles please use BRENDA:EC2.1.1.131
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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.131 precorrin-3B C17-methyltransferase
IUBMB Comments
The enzyme, which participates in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses a crucial reaction where the tetrapyrrole ring contracts as a result of methylation of C-17. See EC 2.1.1.272, cobalt-factor III methyltransferase, for the corresponding enzyme that participates in the anaerobic cobalamin biosynthesis pathway.
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The enzyme appears in viruses and cellular organisms
Synonyms
precorrin-3b methyltransferase, sam-dependent c-17 methyl transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin-4
show the reaction diagram
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