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Information on EC 1.8.1.14 - CoA-disulfide reductase

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EC Tree
     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.14 CoA-disulfide reductase
IUBMB Comments
A flavoprotein. Not identical with EC 1.8.1.6 (cystine reductase), EC 1.8.1.7 (glutathione-disulfide reductase) or EC 1.8.1.13 (bis-gamma-glutamylcystine reductase). The enzyme from the bacterium Staphylococcus aureus has a strong preference for NADPH , while the bacterium Bacillus megaterium contains both NADH and NADPH-dependent enzymes .
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes
Synonyms
BACoADR, BB0728, CoA disulfide reductase, CoA-disulfide reductase (NADH), CoA-disulfide reductase (NADH2), CoADR, coenzyme A disulfide reductase, coenzyme A disulphide reductase, coenzyme A-disulfide reductase, NADH2:CoA-disulfide oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 CoA + NADP+ = CoA-disulfide + NADPH + H+
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PATHWAY SOURCE
PATHWAYS
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