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Information on EC 1.8.1.13 - bis-gamma-glutamylcystine reductase

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IUBMB Comments
Contains FAD. The enzyme, which is found only in halobacteria, maintains the concentration of gamma-glutamylcysteine, the major low molecular weight thiol in halobacteria. Not identical with EC 1.8.1.7 (glutathione-disulfide reductase) or EC 1.8.1.14 (CoA-disulfide reductase).
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The expected taxonomic range for this enzyme is: Halobacterium salinarum
Synonyms
EC 1.6.4.9, GCR, NADPH2:bis-g-glutamylcysteine oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 gamma-glutamylcysteine + NADP+ = bis-gamma-glutamylcystine + NADPH + H+
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highly specific; highly specific. Not identical with EC 1.8.1.7 glutathione-disulfide reductase or EC 1.8.1.14 CoA-disulfide reductase
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PATHWAY SOURCE
PATHWAYS
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