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Information on EC 1.7.2.1 - nitrite reductase (NO-forming)

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IUBMB Comments
The reaction is catalysed by two types of enzymes, found in the perimplasm of denitrifying bacteria. One type comprises proteins containing multiple copper centres, the other a heme protein, cytochrome cd1. Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. May also catalyse the reaction of hydroxylamine reductase (EC 1.7.99.1) since this is a well-known activity of cytochrome cd1.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
AcNIR, AfNiR, AniA, AxNiR, C551-O2 oxidoreductase, cd1 nitrite reductase, cd1NiR, cNOR, copper-containing dissimilatory nitrite reductase, copper-containing nitrite reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+
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