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Information on EC 1.7.1.B2 - aromatic nitroreductase [NAD(P)H]

for references in articles please use BRENDA:EC1.7.1.B2
preliminary BRENDA-supplied EC number
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Synonyms
NfsB, NfsB_Ec, NfsB_Pa, NprA, oxygen-insensitive nitroreductase (NAD(P)H), more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an aromatic amine + 3 NAD(P)+ + 2 H2O = an aromatic nitrate + 3 NAD(P)H + 3 H+
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in vivo the reaction is obseverved in the opposite direction from that shown in the equation; (overall reaction)
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an aromatic amine + NAD(P)+ + H2O = an aromatic hydroxylamine + NAD(P)H + H+
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(1a)
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an aromatic hydroxylamine + NAD(P)+ = an aromatic nitric oxide + NAD(P)H + H+
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(1b)
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an aromatic nitric oxide + NAD(P)+ + H2O = an aromatic nitrate + NAD(P)H + H+
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(1c)
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