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Information on EC 1.7.1.10 - hydroxylamine reductase (NADH) and Organism(s) Porphyromonas gingivalis and UniProt Accession Q7MVY0

for references in articles please use BRENDA:EC1.7.1.10
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IUBMB Comments
Also acts on some hydroxamates.
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This record set is specific for:
Porphyromonas gingivalis
UNIPROT: Q7MVY0
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The taxonomic range for the selected organisms is: Porphyromonas gingivalis
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Synonyms
pg0893, nadh-hydroxylamine reductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ammonium dehydrogenase
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N-hydroxy amine reductase
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NADH-hydroxylamine reductase
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reductase, hydroxylamine
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
ammonium:NAD+ oxidoreductase
Also acts on some hydroxamates.
CAS REGISTRY NUMBER
COMMENTARY hide
9032-06-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
an allelic exchange mutant strain is black pigmented and shows growth rates and gingipain and hemolytic activities similar to those of the wild-type strain. The mutant is more sensitive to nitric oxide than the wild type. The strain shows sensitivity to oxidative stress similar to that of the wild-type strain
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
in cells exposed to nitric oxide, enzyme is upregulated 1.4fold. In addition, 178 genes are upregulated and 201 genes downregulated more than 2fold
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boutrin, M.C.; Wang, C.; Aruni, W.; Li, X.; Fletcher, H.M.
Nitric oxide stress resistance in Porphyromonas gingivalis is mediated by a putative hydroxylamine reductase
J. Bacteriol.
194
1582-1592
2012
Porphyromonas gingivalis (Q7MVY0), Porphyromonas gingivalis, Porphyromonas gingivalis ATCC BAA-308 (Q7MVY0)
Manually annotated by BRENDA team