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Information on EC 1.6.5.10 - NADPH dehydrogenase (quinone)

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IUBMB Comments
A flavoprotein [1, 2]. The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors . Menaquinone can act as acceptor. The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol .
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Synonyms
AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
NADPH + H+ + a quinone = NADP+ + a quinol
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