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Information on EC 1.6.5.10 - NADPH dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.6.5.10

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IUBMB Comments

A flavoprotein [1, 2]. The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors . Menaquinone can act as acceptor. The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol .

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes

Synonyms
nadph oxidase, nadph quinone oxidoreductase 1, nadph quinone oxidoreductase, nadph-quinone oxidoreductase, ppazor, xac2229, pa1225, nadph dehydrogenase (quinone), nadph:(quinone-acceptor) oxidoreductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADPH + H+ + a quinone = NADP+ + a quinol
show the reaction diagram