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Information on EC 1.6.3.3 - NADH oxidase (H2O2-forming)

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EC Tree
     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.3 With oxygen as acceptor
                1.6.3.3 NADH oxidase (H2O2-forming)
IUBMB Comments
A flavoprotein (FAD). The bacterium Streptococcus mutans contains two distinct NADH oxidases, a H2O2-forming enzyme and a H2O-forming enzyme (cf. EC 1.6.3.4, NADH oxidase (H2O-forming)) . The enzymes from the anaerobic archaea Methanocaldococcus jannaschii and Pyrococcus furiosus also produce low amounts of H2O. Unlike EC 1.6.3.1 (NAD(P)H oxidase) it has no activity towards NADPH.
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Word Map
The expected taxonomic range for this enzyme is: Archaea, Eukaryota, Bacteria
Reaction Schemes
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Synonyms
nox-1, noxb-1, noxa2, noxa-1, mj0649, mjnox, h2o2-forming nadh oxidase, af0395, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + H+ + O2 = NAD+ + H2O2
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PATHWAY SOURCE
PATHWAYS
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