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Information on EC 1.6.3.2 - NAD(P)H oxidase (H2O-forming)

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EC Tree
     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.3 With oxygen as acceptor
                1.6.3.2 NAD(P)H oxidase (H2O-forming)
IUBMB Comments
A flavoprotein (FAD). NADPH is a better substrate than NADH [1,3]. By removal of oxygen the enzyme is involved in aerobic tolerance in the thermophilic anaerobic archaeon Thermococcus profundus and in Giardia intestinalis, a microaerophilic single-celled parasite of the order Diplomonadida.
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The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Reaction Schemes
2
+
+
=
2
+
2
Synonyms
noxtp, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 NAD(P)H + 2 H+ + O2 = 2 NAD(P)+ + 2 H2O
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PATHWAY SOURCE
PATHWAYS
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