Reference on EC 1.6.3.1 - NAD(P)H oxidase (H2O2-forming) and Organism(s) Rattus norvegicus and UniProt Accession Q924V1
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
De Deken, X.; Wang, D.; Dumont, J.E.; Miot, F.
Characterization of ThOX proteins as components of the thyroid H2O2-generating system
Exp. Cell Res.
273
187-196
2002
Canis lupus familiaris, Homo sapiens, Rattus norvegicus
Banfi, B.; Malgrange, B.; Knisz, J.; Steger, K.; Dubois-Dauphin, M.; Krause, K.H.
NOX3, a superoxide-generating NADPH oxidase of the inner ear
J. Biol. Chem.
279
46065-46072
2004
Mus musculus (Q672J9), Rattus norvegicus (Q672K1)
Cheranov, S.Y.; Jaggar, J.H.
TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation
Am. J. Physiol.
290
C964-C971
2006
Rattus norvegicus
Liu, Q.; Kang, J.; Zheng, R.
NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes
Cell Biochem. Funct.
23
93-100
2005
Rattus norvegicus
Miller, A.A.; Drummond, G.R.; Schmidt, H.H.; Sobey, C.G.
NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries
Circ. Res.
97
1055-1062
2005
Rattus norvegicus
Maia, L.; Vala, A.; Mira, L.
NADH oxidase activity of rat liver xanthine dehydrogenase and xanthine oxidase-contribution for damage mechanisms
Free Radic. Res.
39
979-986
2005
Rattus norvegicus
Jekabsone, A.; Mander, P.K.; Tickler, A.; Sharpe, M.; Brown, G.C.
Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study
J. Neuroinflammation
3
24
2006
Rattus norvegicus
Wong, K.L.; Wu, K.C.; Wu, R.S.; Chou, Y.H.; Cheng, T.H.; Hong, H.J.
Tetramethylpyrazine inhibits angiotensin II-increased NAD(P)H oxidase activity and subsequent proliferation in rat aortic smooth muscle cells
Am. J. Chin. Med.
35
1021-1035
2007
Rattus norvegicus
Chandramohan, G.; Bai, Y.; Norris, K.; Rodriguez-Iturbe, B.; Vaziri, N.D.
Effects of dietary salt on intrarenal angiotensin system, NAD(P)H oxidase, COX-2, MCP-1 and PAI-1 expressions and NF-kappaB activity in salt-sensitive and -resistant rat kidneys
Am. J. Nephrol.
28
158-167
2008
Rattus norvegicus
Benter, I.F.; Yousif, M.H.; Dhaunsi, G.S.; Kaur, J.; Chappell, M.C.; Diz, D.I.
Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats
Am. J. Nephrol.
28
25-33
2008
Rattus norvegicus
Orosz, Z.; Csiszar, A.; Labinskyy, N.; Smith, K.; Kaminski, P.M.; Ferdinandy, P.; Wolin, M.S.; Rivera, A.; Ungvari, Z.
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation
Am. J. Physiol. Heart Circ. Physiol.
292
H130-H139
2007
Rattus norvegicus
Chen, P.; Guo, A.M.; Edwards, P.A.; Trick, G.; Scicli, A.G.
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis
Am. J. Physiol. Regul. Integr. Comp. Physiol.
293
R1619-R1629
2007
Rattus norvegicus
Murillo, M.M.; Carmona-Cuenca, I.; Del Castillo, G.; Ortiz, C.; Roncero, C.; Sanchez, A.; Fernandez, M.; Fabregat, I.
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism
Biochem. J.
405
251-259
2007
Rattus norvegicus
Sicard, P.; Acar, N.; Gregoire, S.; Lauzier, B.; Bron, A.M.; Creuzot-Garcher, C.; Bretillon, L.; Vergely, C.; Rochette, L.
Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats
Br. J. Pharmacol.
151
979-986
2007
Rattus norvegicus
Campese, V.M.; Sindhu, R.K.; Ye, S.; Bai, Y.; Vaziri, N.D.; Jabbari, B.
Regional expression of NO synthase, NAD(P)H oxidase and superoxide dismutase in the rat brain
Brain Res.
1134
27-32
2007
Rattus norvegicus
Li, B.; Guo, Y.S.; Sun, M.M.; Dong, H.; Wu, S.Y.; Wu, D.X.; Li, C.Y.
The NADPH oxidase is involved in lipopolysaccharide-mediated motor neuron injury
Brain Res.
1226
199-208
2008
Rattus norvegicus
Schlueter, T.; Steinbach, A.C.; Steffen, A.; Rettig, R.; Grisk, O.
Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition
Cardiovasc. Res.
80
271-279
2008
Mus musculus, Rattus norvegicus
Thallas-Bonke, V.; Thorpe, S.R.; Coughlan, M.T.; Fukami, K.; Yap, F.Y.; Sourris, K.C.; Penfold, S.A.; Bach, L.A.; Cooper, M.E.; Forbes, J.M.
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway
Diabetes
57
460-469
2008
Rattus norvegicus
Matthiesen, S.; Lindemann, D.; Warnken, M.; Juergens, U.R.; Racke, K.
Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages
Eur. J. Pharmacol.
579
403-410
2008
Rattus norvegicus
Glass, M.J.; Chan, J.; Frys, K.A.; Oselkin, M.; Tarsitano, M.J.; Iadecola, C.; Pickel, V.M.
Changes in the subcellular distribution of NADPH oxidase subunit p47phox in dendrites of rat dorsomedial nucleus tractus solitarius neurons in response to chronic administration of hypertensive agents
Exp. Neurol.
205
383-395
2007
Rattus norvegicus
Siragy, H.M.; Huang, J.
Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity
Exp. Physiol.
93
709-714
2008
Rattus norvegicus
Chen, C.Y.; Liu, T.Z.; Chen, C.H.; Wu, C.C.; Cheng, J.T.; Yiin, S.J.; Shih, M.K.; Wu, M.J.; Chern, C.L.
Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms
Food Chem. Toxicol.
45
1268-1276
2007
Homo sapiens, Rattus norvegicus
Sheh, Y.L.; Hsu, C.; Chan, S.H.; Chan, J.Y.
NADPH oxidase- and mitochondrion-derived superoxide at rostral ventrolateral medulla in endotoxin-induced cardiovascular depression
Free Radic. Biol. Med.
42
1610-1623
2007
Rattus norvegicus
Liu, S.; Ma, X.; Gong, M.; Shi, L.; Lincoln, T.; Wang, S.
Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species
Free Radic. Biol. Med.
42
852-863
2007
Rattus norvegicus
Coyoy, A.; Valencia, A.; Guemez-Gamboa, A.; Moran, J.
Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons
Free Radic. Biol. Med.
45
1056-1064
2008
Rattus norvegicus
Riazi, S.; Madala-Halagappa, V.K.; Dantas, A.P.; Hu, X.; Ecelbarger, C.A.
Sex differences in renal nitric oxide synthase, NAD(P)H oxidase, and blood pressure in obese Zucker rats
Gend. Med.
4
214-229
2007
Rattus norvegicus
Wei, Y.; Whaley-Connell, A.T.; Chen, K.; Habibi, J.; Uptergrove, G.M.; Clark, S.E.; Stump, C.S.; Ferrario, C.M.; Sowers, J.R.
NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat
Hypertension
50
384-391
2007
Rattus norvegicus
Datla, S.R.; Dusting, G.J.; Mori, T.A.; Taylor, C.J.; Croft, K.D.; Jiang, F.
Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress
Hypertension
50
636-642
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Cao, X.; Dai, X.; Parker, L.M.; Kreulen, D.L.
Differential regulation of NADPH oxidase in sympathetic and sensory ganglia in deoxycorticosterone acetate salt hypertension
Hypertension
50
663-671
2007
Rattus norvegicus
Jackson, E.K.; Gillespie, D.G.; Zhu, C.; Ren, J.; Zacharia, L.C.; Mi, Z.
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA
Hypertension
51
719-726
2008
Rattus norvegicus
Szoecs, K.; Lassegue, B.; Wenzel, P.; Wendt, M.; Daiber, A.; Oelze, M.; Meinertz, T.; Muenzel, T.; Baldus, S.
Increased superoxide production in nitrate tolerance is associated with NAD(P)H oxidase and aldehyde dehydrogenase 2 downregulation
J. Mol. Cell. Cardiol.
42
1111-1118
2007
Rattus norvegicus
Qian, L.; Xu, Z.; Zhang, W.; Wilson, B.; Hong, J.S.; Flood, P.M.
Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
J. Neuroinflammation
4
23
2007
Rattus norvegicus
Zhang, D.; Hu, X.; Wei, S.; Liu, J.; Gao, H.; Qian, L.; Wilson, B.; Liu, G.; Hong, J.
Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity
J. Neuroinflammation
5
21
2008
Mus musculus, Rattus norvegicus
Park, K.W.; Jin, B.K.
Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: role of neuronal NADPH oxidase
J. Neurosci. Res.
86
1053-1063
2008
Rattus norvegicus
Li, H.; Hortmann, M.; Daiber, A.; Oelze, M.; Ostad, M.A.; Schwarz, P.M.; Xu, H.; Xia, N.; Kleschyov, A.L.; Mang, C.; Warnholtz, A.; Muenzel, T.; Foerstermann, U.
Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases
J. Pharmacol. Exp. Ther.
326
745-753
2008
Homo sapiens, Rattus norvegicus
Zhou, J.; Zhang, S.; Zhao, X.; Wei, T.
Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-beta(1-42)
J. Pineal Res.
45
157-165
2008
Rattus norvegicus
Hachisuka, H.; Dusting, G.J.; Abberton, K.M.; Morrison, W.A.; Jiang, F.
Role of NADPH oxidase in tissue growth in a tissue engineering chamber in rats
J. Tissue Eng. Regen. Med.
2
430-435
2008
Rattus norvegicus
Saito, Y.; Geisen, P.; Uppal, A.; Hartnett, M.E.
Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity
Mol. Vis.
13
840-853
2007
Rattus norvegicus
Anantharam, V.; Kaul, S.; Song, C.; Kanthasamy, A.; Kanthasamy, A.G.
Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells
Neurotoxicology
28
988-997
2007
Rattus norvegicus
Chao, H.H.; Chen, C.H.; Liu, J.C.; Lin, J.W.; Wong, K.L.; Cheng, T.H.
L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation
J. Nutr. Biochem.
21
580-588
2010
Rattus norvegicus
Jensen, M.D.; Sheng, W.; Simonyi, A.; Johnson, G.S.; Sun, A.Y.; Sun, G.Y.
Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes
Neurochem. Int.
55
362-368
2009
Rattus norvegicus
El-Benna, J.; Dang, P.M.; Perianin, A.
Peptide-based inhibitors of the phagocyte NADPH oxidase
Biochem. Pharmacol.
80
778-785
2010
Homo sapiens, Rattus norvegicus
Pan, Q.; Yang, X.H.; Cheng, Y.X.
Angiotensin II stimulates MCP-1 production in rat glomerular endothelial cells via NAD(P)H oxidase-dependent nuclear factor-kappa B signaling
Braz. J. Med. Biol. Res.
42
531-536
2009
Rattus norvegicus
Gao, L.; Mann, G.E.
Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling
Cardiovasc. Res.
82
9-20
2009
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Winiarska, K.; Grabowski, M.; Rogacki, M.K.
Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin
Chem. Biol. Interact.
189
119-126
2011
Oryctolagus cuniculus, Rattus norvegicus
Morgan, D.; Rebelato, E.; Abdulkader, F.; Graciano, M.F.; Oliveira-Emilio, H.R.; Hirata, A.E.; Rocha, M.S.; Bordin, S.; Curi, R.; Carpinelli, A.R.
Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells
Endocrinology
150
2197-2201
2009
Rattus norvegicus
Feillet-Coudray, C.; Sutra, T.; Fouret, G.; Ramos, J.; Wrutniak-Cabello, C.; Cabello, G.; Cristol, J.P.; Coudray, C.
Oxidative stress in rats fed a high-fat high-sucrose diet and preventive effect of polyphenols: Involvement of mitochondrial and NAD(P)H oxidase systems
Free Radic. Biol. Med.
46
624-632
2009
Rattus norvegicus
Zhang, R.; Harding, P.; Garvin, J.L.; Juncos, R.; Peterson, E.; Juncos, L.A.; Liu, R.
Isoforms and functions of NAD(P)H oxidase at the macula densa
Hypertension
53
556-563
2009
Rattus norvegicus (Q924V1)
Zhang, Q.G.; Raz, L.; Wang, R.; Han, D.; De Sevilla, L.; Yang, F.; Vadlamudi, R.K.; Brann, D.W.
Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation
J. Neurosci.
29
13823-13836
2009
Rattus norvegicus
Gupte, S.; Labinskyy, N.; Gupte, R.; Csiszar, A.; Ungvari, Z.; Edwards, J.G.
Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM
PLoS ONE
5
e11800
2010
Rattus norvegicus
Polizio, A.H.; Balestrasse, K.B.; Gornalusse, G.G.; Gorzalczany, S.B.; Santa-Cruz, D.M.; Yannarelli, G.G.; Pena, C.; Tomaro, M.L.
Losartan exerts renoprotection through NAD(P)H oxidase downregulation in a renovascular model of hypertension
Regul. Pept.
156
28-33
2009
Rattus norvegicus
Gaete, P.S.; Lillo, M.A.; Ardiles, N.M.; Perez, F.R.; Figueroa, X.F.
Ca2+-activated K+ channels of small and intermediate conductance control eNOS activation through NAD(P)H oxidase
Free Radic. Biol. Med.
52
860-870
2012
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
De Blasio, M.J.; Ramalingam, A.; Cao, A.H.; Prakoso, D.; Ye, J.M.; Pickering, R.; Watson, A.M.D.; de Haan, J.B.; Kaye, D.M.; Ritchie, R.H.
The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy
Eur. J. Pharmacol.
807
12-20
2017
Rattus norvegicus
Matsumoto, M.; Katsuyama, M.; Iwata, K.; Ibi, M.; Zhang, J.; Zhu, K.; Nauseef, W.M.; Yabe-Nishimura, C.
Characterization of N-glycosylation sites on the extracellular domain of NOX1/NADPH oxidase
Free Radic. Biol. Med.
68
196-204
2014
Homo sapiens, Mus musculus, Rattus norvegicus
Cooney, S.J.; Zhao, Y.; Byrnes, K.R.
Characterization of the expression and inflammatory activity of NADPH oxidase after spinal cord injury
Free Radic. Res.
48
929-939
2014
Rattus norvegicus
Quesada, I.; de Paola, M.; Alvarez, M.S.; Hapon, M.B.; Gamarra-Luques, C.; Castro, C.
Antioxidant and anti-atherogenic properties of Prosopis strombulifera and Tessaria absinthioides aqueous extracts modulation of NADPH oxidase-derived reactive oxygen species
Front. Physiol.
12
662833
2021
Mus musculus, Rattus norvegicus
