Reference on EC 1.5.1.53 - methylenetetrahydrofolate reductase (NADPH)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Daubner, S.C.; Matthews, R.G.
Purification and properties of methylenetetrahydrofolate reductase from pig liver
J. Biol. Chem.
257
140-145
1982
Sus scrofa
Zhou, J.; Kang, S.S.; Wong, P.W.; Fournier, B.; Rozen, R.
Purification and characterization of methylenetetrahydrofolate reductase from human cadaver liver
Biochem. Med. Metab. Biol.
43
234-242
1990
Homo sapiens
Matthews, R.; Bobbie, H.
Inhibition of pig liver methylenetetrahydrofolate reductase by dihydrofolate some mechanistic and regulatory implications
Biochemistry
18
4845-4851
1979
Sus scrofa
Vanoni, M.A.; Matthews, R.G.
Kinetic isotope effects on the oxidation of reduced nicotinamide adenine dinucleotide phosphate by the flavoprotein methylenetetrahydrofolate reductase
Biochemistry
23
5272-5279
1984
Sus scrofa
Kutzbach, C.; Stokstad, E.
Mammalian methylenetetrahydrofolate reductase partial purification, properties, and inhibition by S-adenosylmethionine
Biochim. Biophys. Acta
250
459-477
1971
Sus scrofa
Bezerra, G.A.; Holenstein, A.; Foster, W.R.; Xie, B.; Hicks, K.G.; Buerer, C.; Lutz, S.; Mukherjee, A.; Sarkar, D.; Bhattacharya, D.; Rutter, J.; Talukdar, A.; Brown, P.J.; Luo, M.; Shi, L.; Froese, D.S.; Yue, W.W.
Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain
Biochimie
183
100-107
2021
Homo sapiens (P42898)
Sumner, J.; Matthews, R.
Stereochemistry and mechanism of hydrogen transfer between NADPH and methylenetetrahydrofolate in the reaction catalyzed by methylenetetrahydrofolate reductase from pig liver
J. Am. Chem. Soc.
114
6949-6956
1992
Sus scrofa
-
Sobti, P.; Rothenberg, S.P.; Quadros, E.V.
Radioenzymatic assay for reductive catalysis of N(5),N(10)-methylenetetrahydrofolate by methylenetetrahydrofolate reductase
J. Biochem. Biophys. Methods
46
11-20
2000
Rattus norvegicus (D4A7E8)
Matthews, R.G.; Kaufman, S.
Characterization of the dihydropterin reductase activity of pig liver methylenetetrahydrofolate reductase
J. Biol. Chem.
255
6014-6017
1980
Sus scrofa
Daubner, S.C.; Matthews, R.G.
Purification and properties of methylenetetrahydrofolate reductase from pig liver
J. Biol. Chem.
257
140-145
1982
Sus scrofa
Jencks, D.A.; Mathews, R.G.
Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium
J. Biol. Chem.
262
2485-2493
1987
Sus scrofa
Roje, S.; Chan, S.Y.; Kaplan, F.; Raymond, R.K.; Horne, D.W.; Appling, D.R.; Hanson, A.D.
Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo
J. Biol. Chem.
277
4056-4061
2002
Saccharomyces cerevisiae (P53128)
Froese, D.; Kopec, J.; Rembeza, E.; Bezerra, G.; Oberholzer, A.; Suormala, T.; Lutz, S.; Chalk, R.; Borkowska, O.; Baumgartner, M.; Yue, W.
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
Nat. Commun.
9
2261
2018
Homo sapiens (P42898)
Yu, L.; Xu, J.; Liu, L.; Bian, X.; Liu, Y.
Purification and catalytic properties of methylenetetrahydrofolate reductase
Pharm. Biotechnol.
18
300-303
2011
Sus scrofa
-
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