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BRENDA support

Information on EC 1.5.1.27 - 1,2-dehydroreticulinium reductase (NADPH)

for references in articles please use BRENDA:EC1.5.1.27

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IUBMB Comments

Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant. The enzyme does not catalyse the reverse reaction to any significant extent under physiological conditions.

The expected taxonomic range for this enzyme is: Papaver

Synonyms
storr, 1,2-dehydroreticuline reductase, reticuline epimerase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-reticuline + NADP+ = 1,2-dehydroreticulinium + NADPH + H+
show the reaction diagram
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