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Abscess
Hypoxia-inducible factor 1-regulated lysyl oxidase is involved in Staphylococcus aureus abscess formation.
Adenocarcinoma
A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First-Line Treatment of Pancreatic Adenocarcinoma.
Adenocarcinoma
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.
Adenocarcinoma
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.
Adenocarcinoma
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution.
Adenocarcinoma
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Adenocarcinoma
Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma.
Adenocarcinoma of Lung
Comprehensive analysis of competitive endogenous RNA associated with immune infiltration in lung adenocarcinoma.
Adenocarcinoma of Lung
Down-regulation of lysyl oxidase-like 2 (LOXL2) is associated with disease progression in lung adenocarcinomas.
Adenocarcinoma of Lung
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Adenocarcinoma of Lung
LOXL1 Is Regulated by Integrin ?11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity.
Adenocarcinoma of Lung
Lysyl oxidase: A lung adenocarcinoma biomarker of invasion and survival.
Adenocarcinoma of Lung
Lysyl oxidase: a lung adenocarcinoma biomarker of invasion and survival.
Adenocarcinoma of Lung
miR-210 promotes lung adenocarcinoma proliferation, migration, and invasion by targeting lysyl oxidase-like 4.
Albinism
Genetic diseases of copper metabolism.
Albuminuria
Lysyl oxidase like-2 contributes to renal fibrosis in Col4?3/Alport mice.
Albuminuria
Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy.
Alopecia
Progressive hair loss and myocardial degeneration in rough coat mice: reduced lysyl oxidase-like (LOXL) in the skin and heart.
Alzheimer Disease
Evidence for increased lysyl oxidase, the extracellular matrix-forming enzyme, in Alzheimer's disease brain.
Alzheimer Disease
Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type.
Alzheimer Disease
Genetic variants in urinary bladder cancer: collective power of the "wimp SNPs"
Alzheimer Disease
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Mutations in the lysyl oxidase gene are not associated with amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis.
Aneurysm
Absence of TGFbeta signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm.
Aneurysm
Brachial artery aneurysms in Menkes disease.
Aneurysm
Inhibition of aortic aneurysm development in blotchy mice by beta adrenergic blockade independent of altered lysyl oxidase activity.
Aneurysm
Mutations in the lysyl oxidase gene not associated with intracranial aneurysm in central European families.
Aneurysm
The Expression Patterns and Roles of Lysyl Oxidases in Aortic Dissection.
Aneurysm, Dissecting
LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections.
Aneurysm, Dissecting
Overexpression of microRNA-30a contributes to the development of aortic dissection by targeting lysyl oxidase.
Aneurysm, Dissecting
The Expression Patterns and Roles of Lysyl Oxidases in Aortic Dissection.
Anovulation
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Aortic Aneurysm
A novel swine model of abdominal aortic aneurysm.
Aortic Aneurysm
Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.
Aortic Aneurysm
Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice.
Aortic Aneurysm
Increased frequency of congenital heart defects in Menkes disease.
Aortic Aneurysm
Inhibition of aortic aneurysm development in blotchy mice by beta adrenergic blockade independent of altered lysyl oxidase activity.
Aortic Aneurysm
LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice.
Aortic Aneurysm
Marfan syndrome and aortic aneurysm: Lysyl oxidases to the rescue?
Aortic Aneurysm
Porcine Model of Infrarenal Abdominal Aortic Aneurysm.
Aortic Aneurysm
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Aortic Aneurysm
Regulation of lysyl oxidase by interferon-gamma in rat aortic smooth muscle cells.
Aortic Aneurysm, Abdominal
Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.
Aortic Aneurysm, Abdominal
Inhibition of development of experimental abdominal aortic aneurysm by c-jun N-terminal protein kinase inhibitor combined with lysyl oxidase gene modified smooth muscle progenitor cells.
Aortic Aneurysm, Abdominal
LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice.
Aortic Aneurysm, Abdominal
Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.
Aortic Aneurysm, Abdominal
Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
The Role of Lysyl Oxidase Family Members in the Stabilization of Abdominal Aortic Aneurysms.
Aortic Aneurysm, Thoracic
Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.
Aortic Aneurysm, Thoracic
Mechanical behavior and matrisome gene expression in the aneurysm-prone thoracic aorta of newborn lysyl oxidase knockout mice.
Aortic Aneurysm, Thoracic
Moderate aerobic exercise prevents matrix degradation and death in a mouse model of aortic dissection and aneurysm.
Aortic Diseases
LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections.
Aortic Valve Stenosis
MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure.
Arteriosclerosis
Changes in aortic lysyl oxidase activity in diet-induced atherosclerosis in the rabbit.
Arteriosclerosis
Increased lysyl oxidase activity in blood vessels of hypertensive rats and effect of beta-aminopropionitrile on arteriosclerosis.
Arteriovenous Fistula
Inhibition of Lysyl Oxidase with ?-aminopropionitrile Improves Venous Adaptation after Arteriovenous Fistula Creation.
Arthritis
Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen?induced arthritis.
Arthritis, Rheumatoid
A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia.
Arthritis, Rheumatoid
Copper response to rheumatoid arthritis.
Arthritis, Rheumatoid
Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen?induced arthritis.
Astrocytoma
Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes.
Atherosclerosis
Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.
Atherosclerosis
Changes in aortic lysyl oxidase activity in diet-induced atherosclerosis in the rabbit.
Atherosclerosis
Immunohistochemical localization of lysyl oxidase in normal human skin.
Atherosclerosis
The role of lysyl oxidase-like 1 and fibulin-5 in the development of atherosclerosis and pelvic organ prolapse.
Atrial Fibrillation
Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation.
Atrial Fibrillation
Increased serum lysyl oxidase-like 2 levels correlate with the degree of left atrial fibrosis in patients with atrial fibrillation.
Atrial Fibrillation
LOXL2 Inhibitor Attenuates Angiotensin II-Induced Atrial Fibrosis and Vulnerability to Atrial Fibrillation through Inhibition of Transforming Growth Factor Beta-1 Smad2/3 Pathway.
Autoimmune Diseases
Glycoprotein Pathways Altered in Frontotemporal Dementia With Autoimmune Disease.
Benign Paroxysmal Positional Vertigo
A novel genetic variant associated with benign paroxysmal positional vertigo within the LOXL1.
Biliary Atresia
Abundant Expression of Lysyl Oxidase-Like 2 Protein in Intra-Hepatic Bile Ducts of Infants with Biliary Atresia.
Biliary Atresia
Abundant Expression of Lysyl Oxidase-like 2 Protein in Intrahepatic Bile Ducts of Infants With Biliary Atresia.
Blister
Lysyl oxidase-like 2 level and glaucoma surgical outcomes.
Bone Diseases
A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia.
Bone Diseases
Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus.
Bone Diseases, Metabolic
A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia.
Brain Injuries
Beta-aminopropionitrile treatment can accelerate recovery of mice after spinal cord injury.
Brain Injuries
Lysyl oxidase, the extracellular matrix-forming enzyme, in rat brain injury sites.
Brain Neoplasms
Lysyl oxidase genetic variants and the prognosis of glioma.
Brain Neoplasms
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression.
Brain Neoplasms
Site-specific expression of amine oxidases in breast cancer metastases.
Breast Neoplasms
3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition.
Breast Neoplasms
A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.
Breast Neoplasms
A molecular role for lysyl oxidase in breast cancer invasion.
Breast Neoplasms
A Polymorphism in the Lysyl Oxidase Propeptide Domain Accelerates Carcinogen-induced Cancer.
Breast Neoplasms
Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer.
Breast Neoplasms
An Impermeant Ganetespib Analog Inhibits Extracellular Hsp90-Mediated Cancer Cell Migration that Involves Lysyl Oxidase 2-like Protein.
Breast Neoplasms
Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer.
Breast Neoplasms
Association of the G473A polymorphism and expression of lysyl oxidase with breast cancer risk and survival in European women: a hospital-based case-control study.
Breast Neoplasms
Associations Between Elastography Findings and Clinicopathological Factors in Breast Cancer.
Breast Neoplasms
Baicalein Inhibits Epithelial to Mesenchymal Transition via Downregulation of Cyr61 and LOXL-2 in MDA-MB231 Breast Cancer Cells.
Breast Neoplasms
Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis.
Breast Neoplasms
Correction to: Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signaling.
Breast Neoplasms
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.
Breast Neoplasms
Detection of Lysyl Oxidase-Like 2 (LOXL2), a Biomarker of Metastasis from Breast Cancers Using Human Blood Samples.
Breast Neoplasms
Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth.
Breast Neoplasms
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Breast Neoplasms
EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer.
Breast Neoplasms
Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signaling.
Breast Neoplasms
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Breast Neoplasms
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.
Breast Neoplasms
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.
Breast Neoplasms
Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration.
Breast Neoplasms
Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling.
Breast Neoplasms
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Breast Neoplasms
Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.
Breast Neoplasms
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
Breast Neoplasms
Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression.
Breast Neoplasms
LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Breast Neoplasms
LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients.
Breast Neoplasms
LOXL2 in epithelial cell plasticity and tumor progression.
Breast Neoplasms
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Breast Neoplasms
LOXL2 Inhibitors and Breast Cancer Progression.
Breast Neoplasms
LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells.
Breast Neoplasms
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Breast Neoplasms
LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Breast Neoplasms
Lysyl Oxidase 473 G>A Polymorphism and Breast Cancer Susceptibility in Chinese Han Population.
Breast Neoplasms
Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-? signaling in breast cancer cells.
Breast Neoplasms
Lysyl oxidase engineered lipid nanovesicles for the treatment of triple negative breast cancer.
Breast Neoplasms
Lysyl oxidase expression and inhibition in uveal melanoma.
Breast Neoplasms
Lysyl oxidase expression is regulated by the H3K27 demethylase Jmjd3 in tumor-associated M2-like macrophages.
Breast Neoplasms
Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma.
Breast Neoplasms
Lysyl oxidase plays a pivotal role in promoting metastasis of breast cancer cells.
Breast Neoplasms
Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.
Breast Neoplasms
Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Breast Neoplasms
Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex.
Breast Neoplasms
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism.
Breast Neoplasms
Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
Breast Neoplasms
Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.
Breast Neoplasms
Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1.
Breast Neoplasms
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
Breast Neoplasms
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Breast Neoplasms
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.
Breast Neoplasms
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Breast Neoplasms
Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer.
Breast Neoplasms
Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas.
Breast Neoplasms
Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer.
Breast Neoplasms
MCF-7 Cells Expressing Nuclear-associated Lysyl Oxidase-like 2 (LOXL2) Exhibit an Epithelial-to-Mesenchymal Transition (EMT) Phenotype and are Highly Invasive In Vitro.
Breast Neoplasms
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells.
Breast Neoplasms
Novel mechanism for OSM-promoted extracellular matrix remodeling in breast cancer: LOXL2 upregulation and subsequent ECM alignment.
Breast Neoplasms
P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell MDA-MB-231 contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment.
Breast Neoplasms
Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion.
Breast Neoplasms
Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer.
Breast Neoplasms
Platelets are associated with xenograft tumor growth and the clinical malignancy of ovarian cancer through an angiogenesis-dependent mechanism.
Breast Neoplasms
Post-translational Modifications of Recombinant Human Lysyl Oxidase-like 2 (rhLOXL2) Secreted from Drosophila S2 Cells.
Breast Neoplasms
Potential options for managing LOX+ ER- breast cancer patients.
Breast Neoplasms
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Breast Neoplasms
Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts.
Breast Neoplasms
Regulation of Breast Cancer-Induced Osteoclastogenesis by MacroH2A1.2 Involving EZH2-Mediated H3K27me3.
Breast Neoplasms
Retraction Note: Baicalein Inhibits Epithelial to Mesenchymal Transition via Downregulation of Cyr61 and LOXL-2 in MDA-MB231 Breast Cancer Cells.
Breast Neoplasms
RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2.
Breast Neoplasms
Role of extracellular matrix in breast cancer development: a brief update.
Breast Neoplasms
Silencing of lysyl oxidase gene expression by RNA interference suppresses metastasis of breast cancer.
Breast Neoplasms
Site-specific expression of amine oxidases in breast cancer metastases.
Breast Neoplasms
Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling.
Breast Neoplasms
Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer.
Breast Neoplasms
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer.
Breast Neoplasms
Targeting lysyl oxidase for molecular imaging in breast cancer.
Breast Neoplasms
The Lysyl Oxidase Inhibitor, beta-Aminopropionitrile, Diminishes the Metastatic Colonization Potential of Circulating Breast Cancer Cells.
Breast Neoplasms
The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.
Breast Neoplasms
The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells.
Breast Neoplasms
The tumor cell-derived matrix of lobular breast cancer: a new vulnerability.
Breast Neoplasms
The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.
Breast Neoplasms
UXT is a LOX-PP Interacting Protein that Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells.
Breast Neoplasms
[Mechanism of lysyl oxidase (LOX) in breast cancer invasion and metastasis].
Bronchiolitis Obliterans
Constrictive bronchiolitis obliterans. Characterisation of fibrogenesis and lysyl oxidase expression patterns.
Bronchopulmonary Dysplasia
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.
Carcinogenesis
Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer.
Carcinogenesis
Association of expression aberrances and genetic polymorphisms of lysyl oxidase with areca-associated oral tumorigenesis.
Carcinogenesis
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.
Carcinogenesis
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Carcinogenesis
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell lung cancer.
Carcinogenesis
Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy.
Carcinogenesis
EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer.
Carcinogenesis
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 ?e13, in esophageal squamous cell carcinoma.
Carcinogenesis
Identification of LOXL3-associating immune infiltration landscape and prognostic value in hepatocellular carcinoma.
Carcinogenesis
Insilico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors.
Carcinogenesis
Is copper chelation an effective anti-angiogenic strategy for cancer treatment?
Carcinogenesis
LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/?v?3 integrin/FAK-MAPK axis in ICC.
Carcinogenesis
LOXL1 Is Regulated by Integrin ?11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity.
Carcinogenesis
Lysyl oxidase (LOX) family members: rationale and their potential as therapeutic targets for liver fibrosis.
Carcinogenesis
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.
Carcinogenesis
Lysyl oxidase family members in urological tumorigenesis and fibrosis.
Carcinogenesis
Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1.
Carcinogenesis
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Carcinogenesis
Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.
Carcinogenesis
Lysyl Oxidase-Like 4 Fosters an Immunosuppressive Microenvironment During Hepatocarcinogenesis.
Carcinogenesis
Lysyl oxidases: from enzyme activity to extracellular matrix cross-links.
Carcinogenesis
Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
Carcinogenesis
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin.
Carcinogenesis
PKC-MEK-MAPK-dependent signal transduction pathway mediates the stimulation of lysyl oxidase expression by serum and PDGF in rat aortic smooth muscle cells.
Carcinogenesis
Salidroside ameliorated hypoxia-induced tumorigenesis of BxPC-3 cells via downregulating hypoxia-inducible factor (HIF)-1? and LOXL2.
Carcinogenesis
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Carcinogenesis
Transcriptional switching model for the regulation of tumorigenesis and metastasis by the ha-ras oncogene - transcriptional changes in the ha-ras tumor-suppressor gene lysyl oxidase.
Carcinoma
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression.
Carcinoma
A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma.
Carcinoma
A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.
Carcinoma
Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer.
Carcinoma
Characterisation of seven newly established head and neck squamous cell carcinoma cell lines.
Carcinoma
Clinical significance of LOXL4 expression and features of LOXL4-associated protein-protein interaction network in esophageal squamous cell carcinoma.
Carcinoma
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Carcinoma
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Carcinoma
Exploration of potential roles of a new LOXL2 splicing variant using network knowledge in esophageal squamous cell carcinoma.
Carcinoma
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Carcinoma
Functional analysis of LOXL2 in pancreatic carcinoma.
Carcinoma
Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells.
Carcinoma
Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer.
Carcinoma
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 ?e13, in esophageal squamous cell carcinoma.
Carcinoma
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Carcinoma
Insilico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors.
Carcinoma
LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Carcinoma
LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype.
Carcinoma
LOXL2 in epithelial cell plasticity and tumor progression.
Carcinoma
LOXL2 upregulates phosphorylation of ezrin to promote cytoskeletal reorganization and tumor cell invasion.
Carcinoma
LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma.
Carcinoma
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Carcinoma
Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma.
Carcinoma
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC).
Carcinoma
Lysyl oxidase family members in urological tumorigenesis and fibrosis.
Carcinoma
Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia.
Carcinoma
Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer.
Carcinoma
Lysyl oxidase like-4 monoclonal antibody demonstrates therapeutic effect against head and neck squamous cell carcinoma cells and xenografts.
Carcinoma
Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.
Carcinoma
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
Carcinoma
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Carcinoma
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Carcinoma
Lysyl oxidase-like 2 promotes esophageal squamous cell carcinoma cell migration independent of catalytic activity.
Carcinoma
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Carcinoma
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Carcinoma
Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures.
Carcinoma
Overexpression of a novel lysyl oxidase-like gene in human head and neck squamous cell carcinomas.
Carcinoma
PACE4 Proteolytically Processes LOXL2 with little impact on its catalytic activity.
Carcinoma
Platelets are associated with xenograft tumor growth and the clinical malignancy of ovarian cancer through an angiogenesis-dependent mechanism.
Carcinoma
Protein-protein Interaction Network Analyses for Elucidating the Roles of LOXL2-delta72 in Esophageal Squamous Cell Carcinoma.
Carcinoma
Re: Tumour-Suppressive MicroRNA-29s Directly Regulate LOXL2 Expression and Inhibit Cancer Cell Migration and Invasion in Renal Cell Carcinoma.
Carcinoma
Reactive oxygen species promote ovarian cancer progression via the HIF-1?/LOX/E-cadherin pathway.
Carcinoma
Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2.
Carcinoma
Recognition of lysyl oxidase as a potential predictive biomarker for oral squamous cell carcinoma: an immunohistochemical study.
Carcinoma
Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Carcinoma
Reduction of LOX- and LOXL2-mRNA expression in head and neck squamous cell carcinomas.
Carcinoma
Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma.
Carcinoma
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Carcinoma
Selective expression of lysyl oxidase (LOX) in the stromal reactions of broncho-pulmonary carcinomas.
Carcinoma
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Carcinoma
Significance of HIF-1? Expression and LOXL-2 Localization in Progression of Oral Squamous Cell Carcinoma.
Carcinoma
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.
Carcinoma
SMYD3 stimulates EZR and LOXL2 transcription to enhance proliferation, migration and invasion in esophageal squamous cell carcinoma.
Carcinoma
Stromally Derived Lysyl Oxidase Promotes Metastasis of Transforming Growth Factor-?-Deficient Mouse Mammary Carcinomas.
Carcinoma
Switching on-off Snail: LOXL2 versus GSK3beta.
Carcinoma
The Lysyl Oxidase LOX Is Absent in Basal and Squamous Cell Carcinomas and Its Knockdown Induces an Invading Phenotype in a Skin Equivalent Model.
Carcinoma
The upregulation of lysyl oxidase in oral submucous fibrosis and squamous cell carcinoma.
Carcinoma
Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma.
Carcinoma
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Carcinoma
Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma.
Carcinoma
Upregulation of MIAT Regulates LOXL2 Expression by Competitively Binding MiR-29c in Clear Cell Renal Cell Carcinoma.
Carcinoma
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Carcinoma
[Expression of lysyl oxidase gene in upper digestive tract carcinomas and its clinical significance]
Carcinoma, Bronchogenic
Lysyl oxidase expression in bronchogenic carcinoma.
Carcinoma, Ductal
PACE4 Proteolytically Processes LOXL2 with little impact on its catalytic activity.
Carcinoma, Hepatocellular
Cancer-associated fibroblasts up-regulate CCL2, CCL26, IL6 and LOXL2 genes related to promotion of cancer progression in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis.
Carcinoma, Hepatocellular
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Carcinoma, Hepatocellular
Hepatocellular carcinoma cells cause different responses in expressions of cancer-promoting genes in different cancer-associated fibroblasts.
Carcinoma, Hepatocellular
HIF-1? promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment.
Carcinoma, Hepatocellular
Increased Expression of the Matrix-Modifying Enzyme Lysyl Oxidase-Like 2 in Aggressive Hepatocellular Carcinoma with Poor Prognosis.
Carcinoma, Hepatocellular
Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues.
Carcinoma, Hepatocellular
LOXL2 promotes vasculogenic mimicry and tumour aggressiveness in hepatocellular carcinoma.
Carcinoma, Hepatocellular
LOXL2 upregulates hypoxia?inducible factor?1? signaling through Snail?FBP1 axis in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
LOXL4 is downregulated in hepatocellular carcinoma with a favorable prognosis.
Carcinoma, Hepatocellular
Lysyl oxidase assists tumor?initiating cells to enhance angiogenesis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Lysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Lysyl oxidase like 4, a novel target gene of TGF-beta1 signaling, can negatively regulate TGF-beta1-induced cell motility in PLC/PRF/5 hepatoma cells.
Carcinoma, Hepatocellular
Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Carcinoma, Hepatocellular
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Carcinoma, Hepatocellular
The effect of LOXL2 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The Long Noncoding RNA LOXL1-AS1 Promotes the Proliferation, Migration, and Invasion in Hepatocellular Carcinoma.
Carcinoma, Lobular
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1.
Carcinoma, Non-Small-Cell Lung
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Expression and significance of hypoxia inducible factor-1? and lysyl oxidase in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Carcinoma, Non-Small-Cell Lung
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
LOXL1 Is Regulated by Integrin ?11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity.
Carcinoma, Non-Small-Cell Lung
Lysyl oxidase mediates hypoxia-induced radioresistance in non-small cell lung cancer A549 cells.
Carcinoma, Non-Small-Cell Lung
The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer.
Carcinoma, Ovarian Epithelial
The role of Lysyl oxidase in epithelial ovarian cancer.
Carcinoma, Renal Cell
Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures.
Carcinoma, Renal Cell
Re: Tumour-Suppressive MicroRNA-29s Directly Regulate LOXL2 Expression and Inhibit Cancer Cell Migration and Invasion in Renal Cell Carcinoma.
Carcinoma, Renal Cell
Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma.
Carcinoma, Renal Cell
Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma.
Carcinoma, Renal Cell
Upregulation of MIAT Regulates LOXL2 Expression by Competitively Binding MiR-29c in Clear Cell Renal Cell Carcinoma.
Carcinoma, Squamous Cell
A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Carcinoma, Squamous Cell
LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Carcinoma, Squamous Cell
LOXL2 in epithelial cell plasticity and tumor progression.
Carcinoma, Squamous Cell
LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma.
Carcinoma, Squamous Cell
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Carcinoma, Squamous Cell
Lysyl oxidase like-4 monoclonal antibody demonstrates therapeutic effect against head and neck squamous cell carcinoma cells and xenografts.
Carcinoma, Squamous Cell
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Carcinoma, Squamous Cell
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Carcinoma, Squamous Cell
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Carcinoma, Squamous Cell
Overexpression of a novel lysyl oxidase-like gene in human head and neck squamous cell carcinomas.
Carcinoma, Squamous Cell
Reduction of LOX- and LOXL2-mRNA expression in head and neck squamous cell carcinomas.
Carcinoma, Squamous Cell
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
The Lysyl Oxidase LOX Is Absent in Basal and Squamous Cell Carcinomas and Its Knockdown Induces an Invading Phenotype in a Skin Equivalent Model.
Carcinoma, Squamous Cell
The upregulation of lysyl oxidase in oral submucous fibrosis and squamous cell carcinoma.
Carcinoma, Squamous Cell
Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma.
Carcinoma, Squamous Cell
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Cardiomegaly
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice.
Cardiomegaly
Early intervention with a potent endothelin-A/endothelin-B receptor antagonist aggravates left ventricular remodeling after myocardial infarction in rats.
Cardiomegaly
Newer findings on a unified perspective of copper restriction and cardiomyopathy.
Cardiomegaly
TRAF3IP2 Mediates Aldosterone/Salt-Induced Cardiac Hypertrophy and Fibrosis.
Cardiomyopathies
A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction.
Cardiomyopathies
Newer findings on a unified perspective of copper restriction and cardiomyopathy.
Cardiomyopathy, Dilated
Secreted Phospholipase A2-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation-Fibrosis Link.
Cardiomyopathy, Dilated
Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy.
Cardiovascular Diseases
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Cardiovascular Diseases
Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Coronary Artery Diseases.
Cardiovascular Diseases
Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy.
Cardiovascular Diseases
Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.
Carpal Tunnel Syndrome
Lysyl oxidase activity in the cells of flexor retinaculum of individuals with carpal tunnel syndrome.
Cataract
Association of LOXL1 Gene Polymorphisms with Exfoliation Glaucoma Patients.
Cataract
Associations of polymorphisms in LOXL1 and copper chaperone genes with pseudoexfoliation-syndrome-related cataract in a Chinese Uygur population.
Cataract
Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review.
Cataract
Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits.
Cataract
LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma.
Cataract
LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population.
Cataract
LOXL1 Hypermethylation in Pseudoexfoliation Syndrome in the Uighur Population.
Cataract
LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract.
Cataract
Lysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome.
Cerebral Hemorrhage
Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type.
Cerebrovascular Disorders
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Cholangiocarcinoma
67 laminin receptor promotes the malignant potential of tumour cells up-regulating lysyl oxidase-like 2 expression in cholangiocarcinoma.
Cholangiocarcinoma
Impact of stroma LOXL2 overexpression on the prognosis of intrahepatic cholangiocarcinoma.
Cholangiocarcinoma
LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/?v?3 integrin/FAK-MAPK axis in ICC.
Cholangiocarcinoma
The interaction of LOXL2 with GATA6 induces VEGFA expression and angiogenesis in cholangiocarcinoma.
Cholangitis
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
Cholangitis, Sclerosing
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
Cholangitis, Sclerosing
Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease.
Cholestasis
Lysyl oxidase like protein-2 (LOXL-2); a novel marker for prediction of intrahepatic cholestasis of pregnancy.
Cholestasis
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
Cholestasis
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Cholestasis, Intrahepatic
Lysyl oxidase like protein-2 (LOXL-2); a novel marker for prediction of intrahepatic cholestasis of pregnancy.
Choroidal Neovascularization
Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1.
Choroidal Neovascularization
The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization.
Chronic Kidney Disease-Mineral and Bone Disorder
Advanced glycation end products suppress lysyl oxidase and induce bone collagen degradation in a rat model of renal osteodystrophy.
Cleft Palate
Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate.
Cleft Palate
Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Cleft Palate
Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice.
Coinfection
Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial.
Colonic Neoplasms
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Colonic Neoplasms
LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.
Colonic Neoplasms
Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.
Colonic Neoplasms
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Colorectal Neoplasms
A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic
Colorectal Neoplasms
Differential expression of the LOX family genes in human colorectal adenocarcinomas.
Colorectal Neoplasms
Elevated LOXL2 expression by LINC01347/miR-328-5p axis contributes to 5-FU chemotherapy resistance of colorectal cancer.
Colorectal Neoplasms
Evaluation of serum lysyl oxidase as a blood test for colorectal cancer.
Colorectal Neoplasms
Identification and characterization of the promoter of cancer-related gene LOXL2.
Colorectal Neoplasms
LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP.
Colorectal Neoplasms
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Colorectal Neoplasms
Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.
Colorectal Neoplasms
Lysyl oxidase in colorectal cancer.
Colorectal Neoplasms
Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Colorectal Neoplasms
Lysyl oxidase rs1800449 polymorphism and cancer risk among Asians: evidence from a meta-analysis and a case-control study of colorectal cancer.
Colorectal Neoplasms
Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer.
Colorectal Neoplasms
Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
Colorectal Neoplasms
Neutrophils expressing lysyl oxidase-like 4 protein are present in colorectal cancer liver metastases resistant to anti-angiogenic therapy.
Colorectal Neoplasms
Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis.
Colorectal Neoplasms
Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors.
Colorectal Neoplasms
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Colorectal Neoplasms
The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer.
Colorectal Neoplasms
TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles.
Colorectal Neoplasms
ZEB1 promotes colorectal cancer cell invasion and disease progression by enhanced LOXL2 transcription.
Colorectal Neoplasms
[Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis].
Congenital Abnormalities
Differential Molecular Expression of Extracellular Matrix and Inflammatory Genes at the Corneal Cone Apex Drives Focal Weakening in Keratoconus.
Congenital Abnormalities
Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Congenital Abnormalities
Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice.
Congenital Abnormalities
Lysyl oxidase-like 3b is critical for cartilage maturation during zebrafish craniofacial development.
Connective Tissue Diseases
Immunohistochemical localization of lysyl oxidase in normal human skin.
Contracture
Dupuytren's contracture: morphological and biochemical changes in palmar aponeurosis.
Contracture
Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture.
Coronary Artery Disease
Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Coronary Artery Diseases.
Cryptosporidiosis
Trans-suppression of host CDH3 and LOXL4 genes during Cryptosporidium parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNA.
Cutis Laxa
An X-linked form of cutis laxa due to deficiency of lysyl oxidase.
Cutis Laxa
Congenital cutis laxa and lysyl oxidase deficiency.
Cutis Laxa
Defects in the biochemistry of collagen in diseases of connective tissue.
Cutis Laxa
Defining the Clinical, Molecular and Ultrastructural Characteristics in Occipital Horn Syndrome: Two New Cases and Review of the Literature.
Cutis Laxa
Elastin production and degradation in cutis laxa acquisita.
Cutis Laxa
Epigenetic silencing of lysyl oxidase-like-1 through DNA hypermethylation in an autosomal recessive cutis laxa case.
Cutis Laxa
Genetic diseases of copper metabolism.
Cutis Laxa
Lysyl Oxidase Like 1: Biological roles and regulation.
Cutis Laxa
Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts.
Cutis Laxa
X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity.
Cystadenoma
Platelets are associated with xenograft tumor growth and the clinical malignancy of ovarian cancer through an angiogenesis-dependent mechanism.
Cystinosis
Copper deficiency in patients with cystinosis with cysteamine toxicity.
Cysts
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
Diabetes Mellitus
Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus.
Diabetes Mellitus
Increased activity of serum amine oxidases in granuloma annulare, necrobiosis lipoidica and diabetes.
Diabetes Mellitus, Type 2
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Diabetic Foot
Impact of lysyl oxidase (G473A) polymorphism on diabetic foot ulcers.
Diabetic Nephropathies
Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy.
Diabetic Retinopathy
Decreased lysyl oxidase level protects against development of retinal vascular lesions in diabetic retinopathy.
Diabetic Retinopathy
Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy.
Diabetic Retinopathy
High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy.
Diabetic Retinopathy
Homocysteine levels in vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment- its modulating role on lysyl oxidase activity.
Diabetic Retinopathy
Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy.
Diabetic Retinopathy
Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment.
Diabetic Retinopathy
Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy.
Digestive System Neoplasms
Prognostic utility and clinical significance of lysyl oxidase-like 2 protein expression in digestive system cancers.
Diverticulum
Defining the Clinical, Molecular and Ultrastructural Characteristics in Occipital Horn Syndrome: Two New Cases and Review of the Literature.
Down Syndrome
Genetic diseases of copper metabolism.
Dupuytren Contracture
Dupuytren's contracture: morphological and biochemical changes in palmar aponeurosis.
Echinococcosis
Echinococcus multilocularis: relationship between susceptibility/resistance and liver fibrogenesis in experimental mice.
Echinococcosis
Mechanism of collagen network stabilization in human irreversible granulomatous liver fibrosis.
Ehlers-Danlos Syndrome
Defects in the biochemistry of collagen in diseases of connective tissue.
Ehlers-Danlos Syndrome
Genetic diseases of copper metabolism.
Ehlers-Danlos Syndrome
Lysyl oxidase deficiency in Ehlers-Danlos syndrome type V.
Ehlers-Danlos Syndrome
Molecular defects in the Ehlers-Danlos syndrome.
Ehlers-Danlos Syndrome
The Ehlers-Danlos syndromes.
Ehlers-Danlos Syndrome
Type IX Ehlers-Danlos syndrome and Menkes syndrome: the decrease in lysyl oxidase activity is associated with a corresponding deficiency in the enzyme protein.
Endometriosis
Deregulation of LOXL1 and HTRA1 gene expression in endometriosis.
Endometriosis
Dysregulation of Lysyl Oxidase Expression in Lesions and Endometrium of Women With Endometriosis.
Endometriosis
Single-nucleotide polymorphisms in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility.
Eosinophilic Esophagitis
Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-?.
Erectile Dysfunction
Amelioration of Cavernosal Fibrosis and Erectile Function by Lysyl Oxidase Inhibition in a Rat Model of Cavernous Nerve Injury.
Erectile Dysfunction
Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Esophageal Neoplasms
Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis.
Esophageal Neoplasms
Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer.
Esophageal Neoplasms
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Esophageal Squamous Cell Carcinoma
A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Clinical significance of LOXL4 expression and features of LOXL4-associated protein-protein interaction network in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Exploration of potential roles of a new LOXL2 splicing variant using network knowledge in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 ?e13, in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
LOXL2 upregulates phosphorylation of ezrin to promote cytoskeletal reorganization and tumor cell invasion.
Esophageal Squamous Cell Carcinoma
Lysyl oxidase-like 2 promotes esophageal squamous cell carcinoma cell migration independent of catalytic activity.
Esophageal Squamous Cell Carcinoma
Protein-protein Interaction Network Analyses for Elucidating the Roles of LOXL2-delta72 in Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
SMYD3 stimulates EZR and LOXL2 transcription to enhance proliferation, migration and invasion in esophageal squamous cell carcinoma.
Exanthema
Deregulation of LOXL1 and HTRA1 gene expression in endometriosis.
Exfoliation Syndrome
An investigation into LOXL1 variants in black South African individuals with exfoliation syndrome.
Exfoliation Syndrome
Analysis of LOXL1 single nucleotide polymorphisms in Polish population with pseudoexfoliation syndrome.
Exfoliation Syndrome
Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people.
Exfoliation Syndrome
Association between Chronic Obstructive Pulmonary Disease and Exfoliation Syndrome: The Utah Project on Exfoliation Syndrome.
Exfoliation Syndrome
Association between Obstructive Sleep Apnea and Exfoliation Syndrome: The Utah Project on Exfoliation Syndrome.
Exfoliation Syndrome
Association between Polymorphisms in Lysyl Oxidase-Like 1 and Susceptibility to Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Association of LOXL1 common sequence variants in German and Italian patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Exfoliation Syndrome
Association of LOXL1 gene common sequence variants in Jordanian patients with exfoliation syndrome and exfoliative glaucoma.
Exfoliation Syndrome
Association of LOXL1 Gene Polymorphisms with Exfoliation Glaucoma Patients.
Exfoliation Syndrome
Association of LOXL1 gene polymorphisms with exfoliation syndrome/glaucoma and primary open angle glaucoma in a Turkish population.
Exfoliation Syndrome
Association of LOXL1 gene polymorphisms with pseudoexfoliation in the Japanese.
Exfoliation Syndrome
Association of LOXL1 gene with Finnish exfoliation syndrome patients.
Exfoliation Syndrome
Association of LOXL1 polymorphisms with pseudoexfoliation in the Chinese.
Exfoliation Syndrome
Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study.
Exfoliation Syndrome
Association of lysyl oxidase-like 1 gene common sequence variants in Greek patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Exfoliation Syndrome
Association of Lysyl Oxidase-Like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Association of Lysyl Oxidase-like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Association of Lysyl Oxidase-Like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Association of lysyl oxidase-like 1 gene polymorphisms in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in a Spanish population.
Exfoliation Syndrome
Association of lysyl oxidase-like 1 gene polymorphisms with exfoliation syndrome in Koreans.
Exfoliation Syndrome
Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India.
Exfoliation Syndrome
Association of polymorphisms in APOE and LOXL1 with pseudoexfoliation syndrome and pseudoexfoliation glaucoma in a Turkish population.
Exfoliation Syndrome
Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome.
Exfoliation Syndrome
Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review.
Exfoliation Syndrome
Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.
Exfoliation Syndrome
Correlation of the intronic LOXL1 polymorphism rs11638944 with pseudoexfoliation syndrome and glaucoma in a Greek population.
Exfoliation Syndrome
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity.
Exfoliation Syndrome
Ethnicity-based subgroup meta-analysis of the association of LOXL1 polymorphisms with glaucoma.
Exfoliation Syndrome
Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
Exfoliation Syndrome
Evaluation of LOXL1 polymorphisms in exfoliation syndrome in a Chinese population.
Exfoliation Syndrome
Evaluation of LOXL1 polymorphisms in exfoliation syndrome in the Uygur population.
Exfoliation Syndrome
Evaluation of LOXL1 polymorphisms in eyes with exfoliation glaucoma in Japanese.
Exfoliation Syndrome
Evaluation of LOXL1 polymorphisms in primary open-angle glaucoma in southern and northern Chinese.
Exfoliation Syndrome
Evaluation of lysyl oxidase-like 1 gene polymorphisms in pseudoexfoliation syndrome in a Korean population.
Exfoliation Syndrome
Exfoliation syndrome and exfoliation glaucoma-associated LOXL1 variations are not involved in pigment dispersion syndrome and pigmentary glaucoma.
Exfoliation Syndrome
Exfoliation syndrome associated with LOXL1 gene polymorphisms in a Black patient from Latin America: a case report.
Exfoliation Syndrome
Exfoliation Syndrome: A Disease of Autophagy and LOXL1 Proteopathy.
Exfoliation Syndrome
Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.
Exfoliation Syndrome
From epidemiology to lysyl oxidase like one (LOXL1) polymorphisms discovery: phenotyping and genotyping exfoliation syndrome and exfoliation glaucoma in Iceland.
Exfoliation Syndrome
Genetic association of LOXL1 gene variants and exfoliation glaucoma in a Utah cohort.
Exfoliation Syndrome
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.
Exfoliation Syndrome
Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus.
Exfoliation Syndrome
Genetics, Diagnosis, and Monitoring of Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior.
Exfoliation Syndrome
Lack of association between lysyl oxidase-like 1 polymorphism in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in North Indian population.
Exfoliation Syndrome
Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits.
Exfoliation Syndrome
LOXL1 Deficiency in the Lamina Cribrosa as Candidate Susceptibility Factor for a Pseudoexfoliation-Specific Risk of Glaucoma.
Exfoliation Syndrome
LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma.
Exfoliation Syndrome
LOXL1 folding in exfoliation glaucoma.
Exfoliation Syndrome
LOXL1 gene analysis in Turkish patients with exfoliation glaucoma.
Exfoliation Syndrome
LOXL1 gene polymorphism candidates for exfoliation glaucoma are also associated with a risk for primary open-angle glaucoma in a Caucasian population from central Russia.
Exfoliation Syndrome
LOXL1 Gene Polymorphism With Exfoliation Syndrome/Exfoliation Glaucoma: A Meta-Analysis.
Exfoliation Syndrome
LOXL1 gene polymorphisms are associated with exfoliation syndrome/exfoliation glaucoma risk: An updated meta-analysis.
Exfoliation Syndrome
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Exfoliation Syndrome
LOXL1 GENE VARIANTS IN ASSOCIATION WITH EXFOLIATION SYNDROME IN GEORGIAN POPULATION.
Exfoliation Syndrome
LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population.
Exfoliation Syndrome
LOXL1 Hypermethylation in Pseudoexfoliation Syndrome in the Uighur Population.
Exfoliation Syndrome
LOXL1 mutations are associated with exfoliation syndrome in patients from the midwestern United States.
Exfoliation Syndrome
LOXL1 Polymorphisms: Genetic Biomarkers that Presage Environmental Determinants of Exfoliation Syndrome.
Exfoliation Syndrome
LOXL1 promoter haplotypes are associated with exfoliation syndrome in a US Caucasian population.
Exfoliation Syndrome
LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract.
Exfoliation Syndrome
LOXL1-associated candidate epithelial pathomechanisms in exfoliation glaucoma.
Exfoliation Syndrome
Lysyl Oxidase Like 1: Biological roles and regulation.
Exfoliation Syndrome
Lysyl oxidase-like 1 gene in the reversal of promoter risk allele in pseudoexfoliation syndrome.
Exfoliation Syndrome
Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma.
Exfoliation Syndrome
Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome.
Exfoliation Syndrome
Lysyl oxidase-like 1 polymorphisms and exfoliation syndrome in the Japanese population.
Exfoliation Syndrome
Lysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome.
Exfoliation Syndrome
Lysyl oxidase-like protein 1 (LOXL1) gene polymorphisms and exfoliation glaucoma in a Central European population.
Exfoliation Syndrome
Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population.
Exfoliation Syndrome
MALDI MS imaging analysis of apolipoprotein E and lysyl oxidase-like 1 in human lens capsules affected by pseudoexfoliation syndrome.
Exfoliation Syndrome
Mass cytometry and transcriptomic profiling reveal body-wide pathology induced by Loxl1 deficiency.
Exfoliation Syndrome
Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations.
Exfoliation Syndrome
Multiple Gene Polymorphisms Associated with Exfoliation Syndrome in the Uygur Population.
Exfoliation Syndrome
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Exfoliation Syndrome
Novel common variants and susceptible haplotype for exfoliation glaucoma specific to Asian population.
Exfoliation Syndrome
Ocular and systemic manifestations of exfoliation syndrome.
Exfoliation Syndrome
Possible Protective Effect of LOXL1 Variant in the Cohort of Chernobyl Catastrophe Clean-Up Workers.
Exfoliation Syndrome
Prevalence of high-risk alleles in the LOXL1 gene and its association with pseudoexfoliation syndrome and exfoliation glaucoma in a Latin American population.
Exfoliation Syndrome
Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants within Lysyl Oxidase-like 1 in an Irish Population.
Exfoliation Syndrome
Prospects for gene-environment interactions in exfoliation syndrome.
Exfoliation Syndrome
Recent advances in risk factors associated with ocular exfoliation syndrome.
Exfoliation Syndrome
Regulation of lysyl oxidase-like 1 (LOXL1) and elastin-related genes by pathogenic factors associated with pseudoexfoliation syndrome.
Exfoliation Syndrome
Review: The role of LOXL1 in exfoliation syndrome/glaucoma.
Exfoliation Syndrome
Risk for Exfoliation Syndrome in Women With Pelvic Organ Prolapse : A Utah Project on Exfoliation Syndrome (UPEXS) Study.
Exfoliation Syndrome
The association of LOXL1 polymorphisms with exfoliation syndrome/glaucoma: Meta-analysis.
Exfoliation Syndrome
The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas.
Exfoliation Syndrome
The microfibril hypothesis of glaucoma: implications for treatment of elevated intraocular pressure.
Exfoliation Syndrome
The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.
Exfoliation Syndrome
The role of lysyl oxidase-like 1 (LOXL1) in exfoliation syndrome and glaucoma.
Exfoliation Syndrome
The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma.
Exfoliation Syndrome
The T allele of lysyl oxidase-like 1 rs41435250 is a novel risk factor for pseudoexfoliation syndrome and pseudoexfoliation glaucoma independently and through intragenic epistatic interaction.
Exfoliation Syndrome
The use of microarray technology in deciphering the cause of genetic eye diseases: LOXL1 and exfoliation syndrome.
Exfoliation Syndrome
Three Single Nucleotide Polymorphisms of LOXL1' in a Turkish Population with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Exfoliation Syndrome
Variations in LOXL1 associated with exfoliation glaucoma do not affect amine oxidase activity.
Exfoliation Syndrome
[Evaluation of LOXL1 polymorphisms in exfoliation syndrome in the Uygur population].
Exostoses
Defining the Clinical, Molecular and Ultrastructural Characteristics in Occipital Horn Syndrome: Two New Cases and Review of the Literature.
Eye Diseases
Identification of differentially expressed genes in keratoconus epithelium analyzed on microarrays.
Eye Diseases
The use of microarray technology in deciphering the cause of genetic eye diseases: LOXL1 and exfoliation syndrome.
Fatty Liver
Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice.
Fatty Liver
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Fatty Liver
Liver immune responses to inflammatory stimuli in a diet-induced obesity model of zebrafish.
Foot Ulcer
Impact of lysyl oxidase (G473A) polymorphism on diabetic foot ulcers.
Fractures, Spontaneous
Pamidronate treatment improves bone mineral density in children with Menkes disease.
Gingival Overgrowth
Cytokine regulation of gingival fibroblast lysyl oxidase, collagen, and elastin.
Gingival Overgrowth
Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes.
Glaucoma
Analysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma.
Glaucoma
Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma.
Glaucoma
Association between Polymorphisms in Lysyl Oxidase-Like 1 and Susceptibility to Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Glaucoma
Association of LOXL1 common sequence variants in German and Italian patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Glaucoma
Association of LOXL1 gene common sequence variants in Jordanian patients with exfoliation syndrome and exfoliative glaucoma.
Glaucoma
Association of LOXL1 Gene Polymorphisms with Exfoliation Glaucoma Patients.
Glaucoma
Association of LOXL1 gene polymorphisms with exfoliation syndrome/glaucoma and primary open angle glaucoma in a Turkish population.
Glaucoma
Association of LOXL1 gene polymorphisms with pseudoexfoliation in the Japanese.
Glaucoma
Association of LOXL1 polymorphisms with pseudoexfoliation in the Chinese.
Glaucoma
Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study.
Glaucoma
Association of lysyl oxidase-like 1 gene common sequence variants in Greek patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Glaucoma
Association of Lysyl Oxidase-Like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Glaucoma
Association of Lysyl Oxidase-like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Glaucoma
Association of Lysyl Oxidase-Like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.
Glaucoma
Association of lysyl oxidase-like 1 gene polymorphisms in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in a Spanish population.
Glaucoma
Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India.
Glaucoma
Association of polymorphisms in APOE and LOXL1 with pseudoexfoliation syndrome and pseudoexfoliation glaucoma in a Turkish population.
Glaucoma
Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review.
Glaucoma
Common sequence variants in the LOXL1 gene in pigment dispersion syndrome and pigmentary glaucoma.
Glaucoma
Corneal Stiffness and Collagen Cross-Linking Proteins in Glaucoma: Potential for Novel Therapeutic Strategy.
Glaucoma
Correlation of the intronic LOXL1 polymorphism rs11638944 with pseudoexfoliation syndrome and glaucoma in a Greek population.
Glaucoma
Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation.
Glaucoma
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity.
Glaucoma
Ethnicity-Based Differences in the Association of LOXL1 Polymorphisms with Pseudoexfoliation/Pseudoexfoliative Glaucoma: A Meta-Analysis.
Glaucoma
Ethnicity-based subgroup meta-analysis of the association of LOXL1 polymorphisms with glaucoma.
Glaucoma
Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
Glaucoma
Exfoliation syndrome and exfoliation glaucoma-associated LOXL1 variations are not involved in pigment dispersion syndrome and pigmentary glaucoma.
Glaucoma
Exfoliation syndrome in sub-Saharan Africa.
Glaucoma
Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.
Glaucoma
Genetic variants in urinary bladder cancer: collective power of the "wimp SNPs"
Glaucoma
Genetics and genomics of pseudoexfoliation syndrome/glaucoma.
Glaucoma
Genetics of pseudoexfoliation syndrome.
Glaucoma
Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients.
Glaucoma
Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population.
Glaucoma
Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations.
Glaucoma
Lack of association between lysyl oxidase-like 1 polymorphism in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in North Indian population.
Glaucoma
Lack of association between lysyl oxidase-like 1 polymorphisms and primary open angle glaucoma: a meta-analysis.
Glaucoma
LOXL1 Deficiency in the Lamina Cribrosa as Candidate Susceptibility Factor for a Pseudoexfoliation-Specific Risk of Glaucoma.
Glaucoma
LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma.
Glaucoma
LOXL1 folding in exfoliation glaucoma.
Glaucoma
LOXL1 Gene Polymorphism With Exfoliation Syndrome/Exfoliation Glaucoma: A Meta-Analysis.
Glaucoma
LOXL1 gene polymorphisms are associated with exfoliation syndrome/exfoliation glaucoma risk: An updated meta-analysis.
Glaucoma
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Glaucoma
LOXL1 gene variants and their association with pseudoexfoliation glaucoma (XFG) in Spanish patients.
Glaucoma
LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract.
Glaucoma
Lysyl Oxidase Like 1: Biological roles and regulation.
Glaucoma
Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma.
Glaucoma
Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome.
Glaucoma
Lysyl oxidase-like 2 level and glaucoma surgical outcomes.
Glaucoma
Mass cytometry and transcriptomic profiling reveal body-wide pathology induced by Loxl1 deficiency.
Glaucoma
Molecular pathology of pseudoexfoliation syndrome/glaucoma - New insights from LOXL1 gene associations.
Glaucoma
Possible Protective Effect of LOXL1 Variant in the Cohort of Chernobyl Catastrophe Clean-Up Workers.
Glaucoma
Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants within Lysyl Oxidase-like 1 in an Irish Population.
Glaucoma
Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1.
Glaucoma
Review: The role of LOXL1 in exfoliation syndrome/glaucoma.
Glaucoma
Role of Lysyl oxidase-like 1 gene polymorphisms in Pakistani patients with pseudoexfoliative glaucoma.
Glaucoma
The association of LOXL1 polymorphisms with exfoliation syndrome/glaucoma: Meta-analysis.
Glaucoma
The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas.
Glaucoma
The microfibril hypothesis of glaucoma: implications for treatment of elevated intraocular pressure.
Glaucoma
The molecular pathophysiology of pseudoexfoliation glaucoma.
Glaucoma
The Role of LOX and LOXL2 in Scar Formation After Glaucoma Surgery.
Glaucoma
The role of lysyl oxidase-like 1 (LOXL1) in exfoliation syndrome and glaucoma.
Glaucoma
The T allele of lysyl oxidase-like 1 rs41435250 is a novel risk factor for pseudoexfoliation syndrome and pseudoexfoliation glaucoma independently and through intragenic epistatic interaction.
Glaucoma
[Association between LOXL1 gene polymorphisms and primary open angle glaucoma in Sichuan population].
Glaucoma
[New pathogenetic insights into pseudoexfoliation syndrome/glaucoma. Therapeutically relevant?].
Glaucoma, Angle-Closure
The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas.
Glaucoma, Open-Angle
Association between Obstructive Sleep Apnea and Exfoliation Syndrome: The Utah Project on Exfoliation Syndrome.
Glaucoma, Open-Angle
Association of LOXL1 gene polymorphisms with exfoliation syndrome/glaucoma and primary open angle glaucoma in a Turkish population.
Glaucoma, Open-Angle
Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study.
Glaucoma, Open-Angle
Associations of polymorphisms of LOXL1 gene with primary open-angle glaucoma: a meta-analysis based on 5,293 subjects.
Glaucoma, Open-Angle
Common sequence variants in the LOXL1 gene in pigment dispersion syndrome and pigmentary glaucoma.
Glaucoma, Open-Angle
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity.
Glaucoma, Open-Angle
Ethnicity-based subgroup meta-analysis of the association of LOXL1 polymorphisms with glaucoma.
Glaucoma, Open-Angle
Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
Glaucoma, Open-Angle
Evaluation of LOXL1 polymorphisms in primary open-angle glaucoma in southern and northern Chinese.
Glaucoma, Open-Angle
Exfoliation syndrome and exfoliation glaucoma-associated LOXL1 variations are not involved in pigment dispersion syndrome and pigmentary glaucoma.
Glaucoma, Open-Angle
Genetic polymorphism related to exfoliative glaucoma is also associated with primary open-angle glaucoma risk.
Glaucoma, Open-Angle
Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population.
Glaucoma, Open-Angle
Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations.
Glaucoma, Open-Angle
Lack of association between lysyl oxidase-like 1 polymorphisms and primary open angle glaucoma: a meta-analysis.
Glaucoma, Open-Angle
LOXL1 gene polymorphism candidates for exfoliation glaucoma are also associated with a risk for primary open-angle glaucoma in a Caucasian population from central Russia.
Glaucoma, Open-Angle
LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract.
Glaucoma, Open-Angle
Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma.
Glaucoma, Open-Angle
Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome.
Glaucoma, Open-Angle
Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population.
Glaucoma, Open-Angle
Population differences in elastin maturation in optic nerve head tissue and astrocytes.
Glaucoma, Open-Angle
The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.
Glaucoma, Open-Angle
[Association between LOXL1 gene polymorphisms and primary open angle glaucoma in Sichuan population].
Glioblastoma
LCN2-interacting proteins and their expression patterns in brain tumors.
Glioblastoma
LOXL1-AS1 predicts poor prognosis and promotes cell proliferation, migration, and invasion in osteosarcoma.
Glioblastoma
LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells.
Glioblastoma
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression.
Glioblastoma
Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma.
Glioma
Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma.
Glioma
In silico identification of the prognostic biomarkers and therapeutic targets associated with cancer stem cell characteristics of glioma.
Glioma
LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2.
Glioma
LOXL1 regulates cell apoptosis and migration in human neuroglioma U87 and U251 cells via Wnt/?-catenin signaling.
Glioma
LOXL2 Upregulation in Gliomas Drives Tumorigenicity by Activating Autophagy to Promote TMZ Resistance and Trigger EMT.
Glioma
LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells.
Glioma
Lysyl oxidase genetic variants and the prognosis of glioma.
Glioma
Over-expression of lysyl oxidase is associated with poor prognosis and response to therapy of patients with lower grade gliomas.
Glioma
Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma.
Granuloma
Activity and extractability of lysyl oxidase and collagen proteins in developing granuloma tissue.
Granuloma
Inhibition of lysyl oxidase by isoniazid and its effect on wound healing.
Granuloma
Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis.
Granuloma Annulare
Increased activity of serum amine oxidases in granuloma annulare, necrobiosis lipoidica and diabetes.
Head and Neck Neoplasms
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Head and Neck Neoplasms
Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer.
Head and Neck Neoplasms
Vaccination strategy to target lysyl oxidase-like 4 in dendritic cell based immunotherapy for head and neck cancer.
Head and Neck Neoplasms
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Hearing Loss
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Hearing Loss, Conductive
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Heart Defects, Congenital
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Heart Diseases
Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases.
Heart Diseases
Human lysyl oxidase-like 2.
Heart Diseases
Inhibitor of lysyl oxidase improves cardiac function and the collagen/MMP profile in response to volume overload.
Heart Failure
'Mysterious' moose disease in Sweden. Similarities to copper deficiency and/or molybdenosis in cattle and sheep. Biochemical background of clinical signs and organ lesions.
Heart Failure
Collagen cross-linking but not collagen amount associates with elevated filling pressures in hypertensive patients with stage C heart failure: potential role of lysyl oxidase.
Heart Failure
Detrimental role of lysyl oxidase in cardiac remodeling.
Heart Failure
Featured Article: Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling.
Heart Failure
Impact of treatment on myocardial lysyl oxidase expression and collagen cross-linking in patients with heart failure.
Heart Failure
Induction of LOX by TGF-?1/Smad/AP-1 signaling aggravates rat myocardial fibrosis and heart failure.
Heart Failure
Inhibitor of lysyl oxidase improves cardiac function and the collagen/MMP profile in response to volume overload.
Heart Failure
Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy.
Heart Failure
MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure.
Heart Failure
Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase?
Heart Failure
Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment.
Hepatitis
Serum lysyl oxidase activity in chronic liver disease in comparison with serum levels of prolyl hydroxylase and laminin.
Hepatitis
Serum lysyl oxidase activity in patients with various liver diseases.
Hepatitis C
Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial.
Hepatitis, Chronic
Increased lysyl oxidase activity in culture medium of nonparenchymal cells from fibrotic livers.
Hepatitis, Chronic
Serum lysyl oxidase activity in chronic liver disease in comparison with serum levels of prolyl hydroxylase and laminin.
Hepatitis, Chronic
Serum lysyl oxidase activity in patients with various liver diseases.
Hepatoblastoma
Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2.
Hepatolenticular Degeneration
A homozygous nonsense mutation and a combination of two mutations of the Wilson disease gene in patients with different lysyl oxidase activities in cultured fibroblasts.
Hepatolenticular Degeneration
Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2.
Hernias, Diaphragmatic, Congenital
Lysyl oxidase expression is decreased in the developing diaphragm and lungs of nitrofen-induced congenital diaphragmatic hernia.
Hernias, Diaphragmatic, Congenital
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.
Histiocytosis, Sinus
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
HIV Infections
Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4(+) T Lymphocyte Depletion in Treated HIV Infection.
Homocystinuria
Increased plasma copper in patients with homocystinuria due to cystathionine beta-synthase deficiency.
Homocystinuria
Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria.
Hyperalgesia
Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
Hypercholesterolemia
Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.
Hyperhomocysteinemia
[Bone quality markers: pentosidine, homocysteine, and MTHFR polymorphism]
Hyperhomocysteinemia
[Daily practice using the guidelines for prevention and treatment of osteoporosis. How do we realize the bone quality in routine practice using Japanese guideline for osteoporosis prevention and treatment?]
Hypertension
A Modification to a Murine Model for Intracranial Aneurysm Formation and Rupture.
Hypertension
Effect of lysyl oxidase inhibition on angiotensin II-induced arterial hypertension, remodeling, and stiffness.
Hypertension
Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges.
Hypertension
Increased lysyl oxidase activity in blood vessels of hypertensive rats and effect of beta-aminopropionitrile on arteriosclerosis.
Hypertension
Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.
Hypertension
Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
Hypertension
Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension.
Hypertension
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Hypertension
Prediction of marker genes associated with hypertension by bioinformatics analyses.
Hypertension
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Hypertension
The Role of Lysyl Oxidase Family Members in the Stabilization of Abdominal Aortic Aneurysms.
Hypertension
Vasa vasorum formation is associated with rupture of intracranial aneurysms.
Hypertension, Pulmonary
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.
Hypertension, Pulmonary
Suppression of Phosphatidylinositol 3-Kinase/Akt Signaling Attenuates Hypoxia-Induced Pulmonary Hypertension Through the Downregulation of Lysyl Oxidase.
Hypertension, Renovascular
Elevated ischaemia-associated lysyl oxidase activity in delayed graft failure 6-12 months after renal transplantation.
Idiopathic Pulmonary Fibrosis
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Blocking LOXL2 and TGF?1 signalling induces collagen I turnover in precision-cut lung slices derived from patients with idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Correction: Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis (doi: 10.1242/dmm.030114).
Idiopathic Pulmonary Fibrosis
Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial.
Idiopathic Pulmonary Fibrosis
Examining lysyl oxidase-like modulation of collagen architecture in 3D spheroid models of idiopathic pulmonary fibrosis via second-harmonic generation microscopy.
Idiopathic Pulmonary Fibrosis
Lysyl Oxidase Inhibition by Heparin in Idiopathic Pulmonary Fibrosis: Is There Still Hope?
Idiopathic Pulmonary Fibrosis
Lysyl Oxidase Like 1: Biological roles and regulation.
Idiopathic Pulmonary Fibrosis
Lysyl oxidase promotes bleomycin-induced lung fibrosis through modulating inflammation.
Idiopathic Pulmonary Fibrosis
Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Regulation of LOXL2 and SERPINH1 by antitumor microRNA-29a in lung cancer with idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Serum lysyl oxidase like-2 levels and idiopathic pulmonary fibrosis disease progression.
Immunoglobulin G4-Related Disease
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease.
Infections
Collagen metabolism in fibrotic liver. Effects of concanavalin A and aggregated myeloma immunoglobin G.
Infections
Human Influenza A virus causes myocardial and cardiac-specific conduction system infection associated with early inflammation and premature death.
Infections
Trans-suppression of host CDH3 and LOXL4 genes during Cryptosporidium parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNA.
Infertility
Expression of lysyl oxidase and effect of copper chloride and ammonium tetrathiomolybdate on bovine ovarian follicle granulosa cells cultured in serum-free media.
Infertility
Single-nucleotide polymorphisms in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility.
Infertility, Male
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Insulin Resistance
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Intracranial Aneurysm
A Modification to a Murine Model for Intracranial Aneurysm Formation and Rupture.
Intracranial Aneurysm
A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans.
Intracranial Aneurysm
Exome Sequencing Identifies LOXL2 Mutation as a Cause of Familial Intracranial Aneurysm.
Intracranial Aneurysm
Lack of association of Lysyl oxidase (LOX) gene polymorphisms with intracranial aneurysm in a south Indian population.
Intracranial Aneurysm
Mutations in the lysyl oxidase gene not associated with intracranial aneurysm in central European families.
Intracranial Aneurysm
Polymorphisms in Lysyl Oxidase Family Genes Are Associated With Intracranial Aneurysm Susceptibility in a Chinese Population.
Intracranial Aneurysm
Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms.
Ischemic Stroke
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Ischemic Stroke
Lysyl oxidase polymorphisms and ischemic stroke-a case control study.
Keloid
Alteration of collagen composition and cross-linking in keloid tissues.
Keloid
Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling.
Keloid
Pathologic scar formation. Morphologic and biochemical correlates.
Keratoconus
Association of Common Variants in LOX with Keratoconus: A Meta-Analysis.
Keratoconus
Association of Lysyl oxidase (LOX) polymorphisms with the risk of Keratoconus in an Iranian population.
Keratoconus
Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients.
Keratoconus
Attenuation of lysyl oxidase and collagen gene expression in keratoconus patient corneal epithelium corresponds to disease severity.
Keratoconus
Changes in lysyl oxidase (LOX) distribution and its decreased activity in keratoconus corneas.
Keratoconus
Mutational screening of VSX1, SPARC, SOD1, LOX, and TIMP3 in keratoconus.
Keratoconus
Outcomes of Corneal Cross-Linking Correlate With Cone-Specific Lysyl Oxidase Expression in Patients With Keratoconus.
Keratoconus
Plasma homocysteine levels in patients with keratoconus.
Keratoconus
The impairment of lysyl oxidase in keratoconus and in keratoconus-associated disorders.
Keratoconus
Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies.
Keratoconus
[Gene expression of down-regulation of lysyl oxidases family in keratoconus corneal fibroblasts induced by combination of mechanical stretching and prostaglandin E 2].
Keratoconus
[The role of tear acidity and Cu-cofactor of lysyl oxidase activity in the pathogenesis of keratoconus].
Kidney Diseases
Lysyl oxidase like-2 contributes to renal fibrosis in Col4?3/Alport mice.
Laryngeal Neoplasms
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Laryngeal Neoplasms
Expression of Lysyl Oxidase Predictive of Distant Metastasis of Laryngeal Cancer.
Laryngeal Neoplasms
Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer.
Leiomyoma
Erratum to "Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases".
Leiomyoma
Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases.
Leukemia
Tocotrienol-rich fraction from annatto ameliorates expression of lysyl oxidase in human osteoblastic MG-63 cells.
Leukemia, Myeloid, Acute
Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia.
Liver Cirrhosis
Carvacrol Downregulates Lysyl Oxidase Expression and Ameliorates Oxidative Stress in the Liver of Rats with Carbon Tetrachloride-Induced Liver Fibrosis.
Liver Cirrhosis
Co-administration of resveratrol and beta-aminopropionitrile attenuates liver fibrosis development via targeting lysyl oxidase in CCl4-induced liver fibrosis in rats.
Liver Cirrhosis
Coexpression of the lysyl oxidase-like gene (LOXL) and the gene encoding type III procollagen in induced liver fibrosis.
Liver Cirrhosis
Differential fibrotic phenotypes of hepatic stellate cells within 3D liver organoids.
Liver Cirrhosis
Immunohistochemical localization of lysyl oxidase in normal human skin.
Liver Cirrhosis
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Liver Cirrhosis
Knockdown of LOXL1 inhibits TGF-?1-induced proliferation and fibrogenesis of hepatic stellate cells by inhibition of Smad2/3 phosphorylation.
Liver Cirrhosis
LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis.
Liver Cirrhosis
Lysyl oxidase (LOX) family members: rationale and their potential as therapeutic targets for liver fibrosis.
Liver Cirrhosis
Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.
Liver Cirrhosis
Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea.
Liver Cirrhosis
Lysyl oxidase: mechanism, regulation and relationship to liver fibrosis.
Liver Cirrhosis
Mechanism of collagen network stabilization in human irreversible granulomatous liver fibrosis.
Liver Cirrhosis
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.
Liver Cirrhosis
Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal.
Liver Cirrhosis
Serum lysyl oxidase activity in chronic liver disease in comparison with serum levels of prolyl hydroxylase and laminin.
Liver Cirrhosis
Serum lysyl oxidase activity in patients with various liver diseases.
Liver Cirrhosis
Withaferin A reverses bile duct ligation-induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NF?B signaling.
Liver Cirrhosis, Biliary
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
Liver Cirrhosis, Biliary
Serum lysyl oxidase activity in patients with various liver diseases.
Liver Diseases
Increased lysyl oxidase activity in culture medium of nonparenchymal cells from fibrotic livers.
Liver Diseases
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Liver Diseases
Serum lysyl oxidase activity in chronic liver disease in comparison with serum levels of prolyl hydroxylase and laminin.
Liver Diseases
Serum lysyl oxidase activity in patients with various liver diseases.
Liver Diseases
Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial.
Liver Diseases
[Plasma lysyl oxidase activity in human liver disease]
Liver Diseases, Alcoholic
Serum lysyl oxidase activity in patients with various liver diseases.
Liver Neoplasms
Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53.
Liver Neoplasms
Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer.
Liver Neoplasms
Transcriptome analysis of PPAR? target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.
Low Tension Glaucoma
LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open-angle glaucoma, normal tension glaucoma, and cataract.
Low Tension Glaucoma
Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma.
Lung Diseases
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Lung Diseases
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.
Lung Diseases, Interstitial
LOXL2, a copper-dependent monoamine oxidase, activates lung fibroblasts through the TGF-?/Smad pathway.
Lung Diseases, Interstitial
The serum level and significance of lysyl oxidase-like 2 in patients with rheumatoid arthritis-associated interstitial lung disease.
Lung Diseases, Interstitial
[Blood copper levels in a group of patients with asbestosis]
Lung Injury
Significance of nuclear LOXL2 inhibition in fibroblasts and myofibroblasts in the fibrotic process of acute respiratory distress syndrome.
Lung Injury
Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury.
Lung Injury
The influence of proline analogs on bleomycin-induced lung injury in rats.
Lung Neoplasms
Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide.
Lung Neoplasms
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell lung cancer.
Lung Neoplasms
Down-regulation of lysyl oxidase-like 2 (LOXL2) is associated with disease progression in lung adenocarcinomas.
Lung Neoplasms
Down-regulation of MBNL1-AS1 contributes to tumorigenesis of NSCLC via sponging miR-135a-5p.
Lung Neoplasms
Downregulation of lysyl oxidase-like 4 LOXL4 by miR-135a-5p promotes lung cancer progression in vitro and in vivo.
Lung Neoplasms
Expression and significance of hypoxia inducible factor-1? and lysyl oxidase in non-small cell lung cancer.
Lung Neoplasms
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Lung Neoplasms
Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients.
Lung Neoplasms
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Lung Neoplasms
LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling.
Lung Neoplasms
LOXL1 Is Regulated by Integrin ?11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity.
Lung Neoplasms
Lysyl oxidase expression in bronchogenic carcinoma.
Lung Neoplasms
Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.
Lung Neoplasms
Lysyl oxidase mediates hypoxia-induced radioresistance in non-small cell lung cancer A549 cells.
Lung Neoplasms
miR-210 promotes lung adenocarcinoma proliferation, migration, and invasion by targeting lysyl oxidase-like 4.
Lung Neoplasms
MiR-504 inhibits cell proliferation and invasion by targeting LOXL2 in non small cell lung cancer.
Lung Neoplasms
Regulation of LOXL2 and SERPINH1 by antitumor microRNA-29a in lung cancer with idiopathic pulmonary fibrosis.
Lung Neoplasms
Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.
Lung Neoplasms
Roles of Ki-67, p53, transforming growth factor-? and lysyl oxidase in the metastasis of lung cancer.
Lung Neoplasms
The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer.
Lung Neoplasms
The Lysyl Oxidase Propeptide Interacts with the Receptor-Type Protein Tyrosine Phosphatase Kappa and Inhibits {beta}-Catenin Transcriptional Activity in Lung Cancer Cells.
Lung Neoplasms
[Effects of lysyl oxidase down-regulation on invasion, migration and E-cadherin protein expression of hypoxic lung cancer cells].
Lymphatic Metastasis
Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.
Lymphatic Metastasis
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Lymphatic Metastasis
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Lymphatic Metastasis
Exposure to desflurane anesthesia confers colorectal cancer cells metastatic capacity through deregulation of miR-34a/LOXL3.
Lymphatic Metastasis
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Lymphatic Metastasis
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Lymphatic Metastasis
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC).
Lymphatic Metastasis
Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.
Lymphatic Metastasis
Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway.
Lymphatic Metastasis
Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer.
Lymphatic Metastasis
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Lymphatic Metastasis
Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT.
Lymphatic Metastasis
Prognostic utility and clinical significance of lysyl oxidase-like 2 protein expression in digestive system cancers.
Lymphatic Metastasis
Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Lymphatic Metastasis
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Lymphatic Metastasis
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Lymphatic Metastasis
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.
Lymphatic Metastasis
Vaccination strategy to target lysyl oxidase-like 4 in dendritic cell based immunotherapy for head and neck cancer.
Lymphatic Metastasis
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Macular Degeneration
Genetic variants in urinary bladder cancer: collective power of the "wimp SNPs"
Macular Degeneration
Interaction of two functional genetic variants LOXL1 rs1048661 and VEGFA rs3025039 on the risk of age-related macular degeneration in Chinese women.
Macular Degeneration
Polymorphisms in ARMS2 (LOC387715) and LOXL1 genes in the Japanese with age-related macular degeneration.
Macular Degeneration
Polymorphisms in ARMS2 (LOC387715) and LOXL1 Genes in the Japanese With Age-Related Macular Degeneration.
Marfan Syndrome
Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.
Marfan Syndrome
Lysyl oxidase activity and synthesis of desmosines in cultured human aortic cells and skin fibroblasts: comparison of cell lines from control subjects and patients with the Marfan syndrome or other annulo-aortic ectasia.
Marfan Syndrome
Lysyl oxidase in osteogenesis imperfecta and Marfan's syndrome.
Marfan Syndrome
Marfan syndrome and aortic aneurysm: Lysyl oxidases to the rescue?
Marfan Syndrome
[Cardiovascular pathology of Marfan syndrome]
Medulloblastoma
LOXL1-AS1 predicts poor prognosis and promotes cell proliferation, migration, and invasion in osteosarcoma.
Melanoma
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Melanoma
Biophytum sensitivum (L.) DC inhibits tumor cell invasion and metastasis through a mechanism involving regulation of MMPs, prolyl hydroxylase, lysyl oxidase, nm23, ERK-1, ERK-2, STAT-1, and proinflammatory cytokine gene expression in metastatic lung tissue.
Melanoma
Divergent roles of lysyl oxidase family members in ornithine decarboxylase- and RAS-transformed mouse fibroblasts and human melanoma cells.
Melanoma
Evaluation of Fluorine-18-Labeled ?1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.
Melanoma
Immunohistochemistry analysis reveals lysyl oxidase-like 3 as a novel prognostic marker for primary melanoma.
Melanoma
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.
Melanoma
Lysyl oxidase expression and inhibition in uveal melanoma.
Melanoma
Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.
Melanoma
Vernonia cinerea Less. Inhibits Tumor Cell Invasion and Pulmonary Metastasis in C57BL/6 Mice.
Menkes Kinky Hair Syndrome
A homozygous nonsense mutation and a combination of two mutations of the Wilson disease gene in patients with different lysyl oxidase activities in cultured fibroblasts.
Menkes Kinky Hair Syndrome
Biochemical indicator for evaluation of connective tissue abnormalities in Menkes' disease.
Menkes Kinky Hair Syndrome
Brachial artery aneurysms in Menkes disease.
Menkes Kinky Hair Syndrome
Expression and accumulation of lysyl oxidase, elastin, and type I procollagen in human Menkes and mottled mouse fibroblasts.
Menkes Kinky Hair Syndrome
Expression of mRNAs for lysyl oxidase and type III procollagen in cultured fibroblasts from patients with the Menkes and occipital horn syndromes as determined by quantitative polymerase chain reaction.
Menkes Kinky Hair Syndrome
Increased frequency of congenital heart defects in Menkes disease.
Menkes Kinky Hair Syndrome
Markedly reduced activity of lysyl oxidase in skin and aorta from a patient with Menkes' disease showing unusually severe connective tissue manifestations.
Menkes Kinky Hair Syndrome
Severe bilateral panlobular emphysema and pulmonary arterial hypoplasia: unusual manifestations of Menkes disease.
Menkes Kinky Hair Syndrome
Type IX Ehlers-Danlos syndrome and Menkes syndrome: the decrease in lysyl oxidase activity is associated with a corresponding deficiency in the enzyme protein.
Mesothelioma, Malignant
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Metabolic Syndrome
Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?
Metabolic Syndrome
Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome.
Microaneurysm
Blood Vessel Basement Membrane Alterations in Human Retinal Microaneurysms During Aging.
Mitochondrial Myopathies
Genetic diseases of copper metabolism.
Mouth Neoplasms
Lysyl oxidase in oral cancer: Friend or foe?
Mouth Neoplasms
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Myocardial Infarction
Immunohistochemical detection of differentially localized up-regulation of lysyl oxidase and down-regulation of matrix metalloproteinase-1 in rhesus monkey model of chronic myocardial infarction.
Myocardial Infarction
Lysyl oxidase expression in cardiac fibroblasts is regulated by ?2?1 integrin interactions with the cellular microenvironment.
Myocardial Infarction
Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction.
Myocardial Ischemia
Decreased copper concentrations but increased lysyl oxidase activity in ischemic hearts of rhesus monkeys.
Myocarditis
Secreted Phospholipase A2-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation-Fibrosis Link.
Myoma
The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.
Myopia
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Myopia
Exome sequencing identified null mutations in LOXL3 associated with early-onset high myopia.
Nasopharyngeal Carcinoma
Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma.
Necrobiosis Lipoidica
Increased activity of serum amine oxidases in granuloma annulare, necrobiosis lipoidica and diabetes.
Neoplasm Metastasis
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Neoplasm Metastasis
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.
Neoplasm Metastasis
Biophytum sensitivum (L.) DC inhibits tumor cell invasion and metastasis through a mechanism involving regulation of MMPs, prolyl hydroxylase, lysyl oxidase, nm23, ERK-1, ERK-2, STAT-1, and proinflammatory cytokine gene expression in metastatic lung tissue.
Neoplasm Metastasis
Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate.
Neoplasm Metastasis
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases.
Neoplasm Metastasis
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway.
Neoplasm Metastasis
Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis.
Neoplasm Metastasis
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Neoplasm Metastasis
Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.
Neoplasm Metastasis
Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases.
Neoplasm Metastasis
Comprehensive analysis on the expression levels and prognostic values of LOX family genes in kidney renal clear cell carcinoma.
Neoplasm Metastasis
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell lung cancer.
Neoplasm Metastasis
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.
Neoplasm Metastasis
Deregulation of FoxM1b leads to tumour metastasis.
Neoplasm Metastasis
Detection of Lysyl Oxidase-Like 2 (LOXL2), a Biomarker of Metastasis from Breast Cancers Using Human Blood Samples.
Neoplasm Metastasis
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Neoplasm Metastasis
Divergent roles of lysyl oxidase family members in ornithine decarboxylase- and RAS-transformed mouse fibroblasts and human melanoma cells.
Neoplasm Metastasis
Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways.
Neoplasm Metastasis
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Neoplasm Metastasis
Emerging role of LOXL2 in the promotion of pancreas cancer metastasis.
Neoplasm Metastasis
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Neoplasm Metastasis
Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression.
Neoplasm Metastasis
Evaluation of Fluorine-18-Labeled ?1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.
Neoplasm Metastasis
Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis.
Neoplasm Metastasis
Exposure to desflurane anesthesia confers colorectal cancer cells metastatic capacity through deregulation of miR-34a/LOXL3.
Neoplasm Metastasis
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Expression of Lysyl Oxidase Predictive of Distant Metastasis of Laryngeal Cancer.
Neoplasm Metastasis
EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer.
Neoplasm Metastasis
Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter.
Neoplasm Metastasis
Functional analysis of LOXL2 in pancreatic carcinoma.
Neoplasm Metastasis
HIF-1? promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment.
Neoplasm Metastasis
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Neoplasm Metastasis
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.
Neoplasm Metastasis
Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells.
Neoplasm Metastasis
Hypoxia-mediated metastasis.
Neoplasm Metastasis
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 ?e13, in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Identification of functional hypoxia inducible factor response elements in the human lysyl oxidase gene promoter.
Neoplasm Metastasis
Impact of lysyl oxidase (G473A) polymorphism on diabetic foot ulcers.
Neoplasm Metastasis
Increased expression of hypoxia-inducible factor-1 alpha and its impact on transcriptional changes and prognosis in malignant tumours of the ocular adnexa.
Neoplasm Metastasis
Increased Expression of the Matrix-Modifying Enzyme Lysyl Oxidase-Like 2 in Aggressive Hepatocellular Carcinoma with Poor Prognosis.
Neoplasm Metastasis
Increased lysyl oxidase-like 2 associates with a poor prognosis in non-small cell lung cancer.
Neoplasm Metastasis
Inhibition of Metastasis of B16F-10 Melanoma Cells in C57BL/6 Mice by an Extract of Calendula Officinalis L Flowers.
Neoplasm Metastasis
Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited.
Neoplasm Metastasis
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
Neoplasm Metastasis
Insilico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors.
Neoplasm Metastasis
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1.
Neoplasm Metastasis
Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression.
Neoplasm Metastasis
Ionizing radiation induces tumor cell lysyl oxidase secretion.
Neoplasm Metastasis
LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.
Neoplasm Metastasis
LOXL 2 Promotes The Epithelial-Mesenchymal Transition And Malignant Progression Of Cervical Cancer.
Neoplasm Metastasis
LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/?v?3 integrin/FAK-MAPK axis in ICC.
Neoplasm Metastasis
LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP.
Neoplasm Metastasis
LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Neoplasm Metastasis
LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients.
Neoplasm Metastasis
LOXL2 in cancer: Regulation, downstream effectors and novel roles.
Neoplasm Metastasis
LOXL2 in epithelial cell plasticity and tumor progression.
Neoplasm Metastasis
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Neoplasm Metastasis
LOXL2 Inhibitors and Breast Cancer Progression.
Neoplasm Metastasis
LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.
Neoplasm Metastasis
LOXL2 promotes vasculogenic mimicry and tumour aggressiveness in hepatocellular carcinoma.
Neoplasm Metastasis
LOXL2 upregulates hypoxia?inducible factor?1? signaling through Snail?FBP1 axis in hepatocellular carcinoma cells.
Neoplasm Metastasis
LOXL2 upregulates phosphorylation of ezrin to promote cytoskeletal reorganization and tumor cell invasion.
Neoplasm Metastasis
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Neoplasm Metastasis
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.
Neoplasm Metastasis
LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells.
Neoplasm Metastasis
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Neoplasm Metastasis
LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Neoplasm Metastasis
Lysyl Oxidase (LOX) and Hypoxia-Induced Metastases.
Neoplasm Metastasis
Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-? signaling in breast cancer cells.
Neoplasm Metastasis
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Neoplasm Metastasis
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC).
Neoplasm Metastasis
Lysyl oxidase expression is regulated by the H3K27 demethylase Jmjd3 in tumor-associated M2-like macrophages.
Neoplasm Metastasis
Lysyl oxidase in cancer inhibition and metastasis.
Neoplasm Metastasis
Lysyl oxidase in cancer research.
Neoplasm Metastasis
Lysyl oxidase in colorectal cancer.
Neoplasm Metastasis
Lysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma.
Neoplasm Metastasis
Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness.
Neoplasm Metastasis
Lysyl oxidase is essential for hypoxia-induced metastasis.
Neoplasm Metastasis
Lysyl oxidase is induced by cell density-mediated cell cycle suppression via RB-E2F1-HIF-1? axis.
Neoplasm Metastasis
Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma.
Neoplasm Metastasis
Lysyl oxidase may play a critical role in hypoxia-induced NSCLC cells invasion and migration.
Neoplasm Metastasis
Lysyl oxidase mediates hypoxia-induced radioresistance in non-small cell lung cancer A549 cells.
Neoplasm Metastasis
Lysyl oxidase mediates hypoxic control of metastasis.
Neoplasm Metastasis
Lysyl oxidase plays a pivotal role in promoting metastasis of breast cancer cells.
Neoplasm Metastasis
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts.
Neoplasm Metastasis
Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis.
Neoplasm Metastasis
Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
Neoplasm Metastasis
Lysyl Oxidase, Extracellular Matrix Remodeling and Cancer Metastasis.
Neoplasm Metastasis
Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.
Neoplasm Metastasis
Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1.
Neoplasm Metastasis
Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.
Neoplasm Metastasis
Lysyl oxidase-like 2 is a regulator of angiogenesis through modulation of endothelial-to-mesenchymal transition.
Neoplasm Metastasis
Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.
Neoplasm Metastasis
Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer.
Neoplasm Metastasis
Lysyl oxidase-like 2 promotes esophageal squamous cell carcinoma cell migration independent of catalytic activity.
Neoplasm Metastasis
Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.
Neoplasm Metastasis
Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway.
Neoplasm Metastasis
Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer.
Neoplasm Metastasis
Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer.
Neoplasm Metastasis
Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
Neoplasm Metastasis
Lysyl oxidase: a potential target for cancer therapy.
Neoplasm Metastasis
Lysyl oxidases: from enzyme activity to extracellular matrix cross-links.
Neoplasm Metastasis
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Neoplasm Metastasis
Model Combining Tumor Molecular and Clinicopathologic Risk Factors Predicts Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma.
Neoplasm Metastasis
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells.
Neoplasm Metastasis
Neutrophils expressing lysyl oxidase-like 4 protein are present in colorectal cancer liver metastases resistant to anti-angiogenic therapy.
Neoplasm Metastasis
Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.
Neoplasm Metastasis
Opening the LOX to bone metastasis: The role of secreted lysyl oxidase in skeletal recurrence of breast cancers.
Neoplasm Metastasis
Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis.
Neoplasm Metastasis
Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT.
Neoplasm Metastasis
Potential options for managing LOX+ ER- breast cancer patients.
Neoplasm Metastasis
Prognostic utility and clinical significance of lysyl oxidase-like 2 protein expression in digestive system cancers.
Neoplasm Metastasis
Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Regulation of lysyl oxidase expression in THP-1 cell-derived M2-like macrophages.
Neoplasm Metastasis
Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma.
Neoplasm Metastasis
Retraction Note: Lysyl oxidase is essential for hypoxia-induced metastasis.
Neoplasm Metastasis
RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2.
Neoplasm Metastasis
Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis.
Neoplasm Metastasis
Roles of Ki-67, p53, transforming growth factor-? and lysyl oxidase in the metastasis of lung cancer.
Neoplasm Metastasis
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Neoplasm Metastasis
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Neoplasm Metastasis
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.
Neoplasm Metastasis
Silencing of lysyl oxidase gene expression by RNA interference suppresses metastasis of breast cancer.
Neoplasm Metastasis
Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway.
Neoplasm Metastasis
Simultaneously targeting cancer-associated fibroblasts and angiogenic vessel as a treatment for TNBC.
Neoplasm Metastasis
Site-specific expression of amine oxidases in breast cancer metastases.
Neoplasm Metastasis
Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling.
Neoplasm Metastasis
Stromally Derived Lysyl Oxidase Promotes Metastasis of Transforming Growth Factor-?-Deficient Mouse Mammary Carcinomas.
Neoplasm Metastasis
Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer.
Neoplasm Metastasis
The function and mechanisms of action of LOXL2 in cancer (Review).
Neoplasm Metastasis
The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.
Neoplasm Metastasis
The pathological significance of LOXL2 in pre-metastatic niche formation of HCC and its related molecular mechanism.
Neoplasm Metastasis
The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer.
Neoplasm Metastasis
The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis.
Neoplasm Metastasis
Transcriptional switching model for the regulation of tumorigenesis and metastasis by the ha-ras oncogene - transcriptional changes in the ha-ras tumor-suppressor gene lysyl oxidase.
Neoplasm Metastasis
Tumor-secreted LOXL2 Activates Fibroblasts Through FAK Signaling.
Neoplasm Metastasis
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Neoplasm Metastasis
Vaccination strategy to target lysyl oxidase-like 4 in dendritic cell based immunotherapy for head and neck cancer.
Neoplasm Metastasis
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Neoplasm Metastasis
ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis.
Neoplasm Metastasis
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Neoplasm Metastasis
[Mechanism of lysyl oxidase (LOX) in breast cancer invasion and metastasis].
Neoplasms
2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
Neoplasms
67 laminin receptor promotes the malignant potential of tumour cells up-regulating lysyl oxidase-like 2 expression in cholangiocarcinoma.
Neoplasms
A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples.
Neoplasms
A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.
Neoplasms
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression.
Neoplasms
A novel asymmetric 3D in-vitro assay for the study of tumor cell invasion.
Neoplasms
A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma.
Neoplasms
A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First-Line Treatment of Pancreatic Adenocarcinoma.
Neoplasms
A Polymorphism in the Lysyl Oxidase Propeptide Domain Accelerates Carcinogen-induced Cancer.
Neoplasms
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Neoplasms
A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2.
Neoplasms
A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.
Neoplasms
Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma.
Neoplasms
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.
Neoplasms
Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer.
Neoplasms
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Neoplasms
An Impermeant Ganetespib Analog Inhibits Extracellular Hsp90-Mediated Cancer Cell Migration that Involves Lysyl Oxidase 2-like Protein.
Neoplasms
Analysis of lysyl oxidase as a marker for diagnosis of canine mammary tumors.
Neoplasms
Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.
Neoplasms
Associations Between Elastography Findings and Clinicopathological Factors in Breast Cancer.
Neoplasms
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.
Neoplasms
Author Correction: Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface.
Neoplasms
Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts.
Neoplasms
beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase.
Neoplasms
Biophytum sensitivum (L.) DC inhibits tumor cell invasion and metastasis through a mechanism involving regulation of MMPs, prolyl hydroxylase, lysyl oxidase, nm23, ERK-1, ERK-2, STAT-1, and proinflammatory cytokine gene expression in metastatic lung tissue.
Neoplasms
Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours.
Neoplasms
Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide.
Neoplasms
Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate.
Neoplasms
Cancer Associated Fibroblasts and Senescent Thyroid Cells in the Invasive Front of Thyroid Carcinoma.
Neoplasms
Cancer-associated fibroblasts up-regulate CCL2, CCL26, IL6 and LOXL2 genes related to promotion of cancer progression in hepatocellular carcinoma cells.
Neoplasms
Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.
Neoplasms
Characterization of recombinant lysyl oxidase propeptide.
Neoplasms
Circular RNA circ_0000228 promotes the malignancy of cervical cancer via microRNA-195-5p/ lysyl oxidase-like protein 2 axis.
Neoplasms
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Neoplasms
Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma.
Neoplasms
Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion.
Neoplasms
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.
Neoplasms
Combined effects of tumor necrosis factor-? and interleukin-1? on lysyl oxidase and matrix metalloproteinase expression in human knee synovial fibroblasts
Neoplasms
Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.
Neoplasms
Comparative functional study of the lysyl oxidase promoter in fibroblasts, Ras-transformed fibroblasts, myofibroblasts and smooth muscle cells.
Neoplasms
Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases.
Neoplasms
Comprehensive analysis on the expression levels and prognostic values of LOX family genes in kidney renal clear cell carcinoma.
Neoplasms
Control of lysyl oxidase activity through site-specific deuteration of lysine.
Neoplasms
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell lung cancer.
Neoplasms
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.
Neoplasms
Deficient production of lysyl oxidase in cultures of malignantly transformed human cells.
Neoplasms
Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved.
Neoplasms
Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53.
Neoplasms
Desmoplasia in pancreatic cancer. Can we fight it?
Neoplasms
Detection of Lysyl Oxidase-Like 2 (LOXL2), a Biomarker of Metastasis from Breast Cancers Using Human Blood Samples.
Neoplasms
Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide.
Neoplasms
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Neoplasms
Differential expression of the LOX family genes in human colorectal adenocarcinomas.
Neoplasms
Divergent roles of lysyl oxidase family members in ornithine decarboxylase- and RAS-transformed mouse fibroblasts and human melanoma cells.
Neoplasms
Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth.
Neoplasms
Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene.
Neoplasms
Down-regulation of lysyl oxidase-like 2 (LOXL2) is associated with disease progression in lung adenocarcinomas.
Neoplasms
Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development.
Neoplasms
Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways.
Neoplasms
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Neoplasms
Emerging role of LOXL2 in the promotion of pancreas cancer metastasis.
Neoplasms
Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone.
Neoplasms
Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity.
Neoplasms
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Neoplasms
Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.
Neoplasms
Evaluation of Fluorine-18-Labeled ?1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.
Neoplasms
Evidence, Mechanism, and Clinical Relevance of the Transdifferentiation from Lung Adenocarcinoma to Squamous Cell Carcinoma.
Neoplasms
Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy.
Neoplasms
Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis.
Neoplasms
Expression of LOXs and MMP-1, 2, 3 by ACL Fibroblasts and Synoviocytes Impact of Coculture and TNF-?.
Neoplasms
Expression of lysyl oxidase in human osteosarcoma and its clinical significance: A tumor suppressive role of LOX in human osteosarcoma cells.
Neoplasms
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Neoplasms
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Neoplasms
Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Neoplasms
Extracellular processing of lysyl oxidase-like 2 and its effect on amine oxidase activity.
Neoplasms
EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer.
Neoplasms
Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis.
Neoplasms
Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells.
Neoplasms
Heparanase 2 attenuates head and neck tumor vascularity and growth.
Neoplasms
Heparanase 2 expression inversely correlates with bladder carcinoma grade and stage.
Neoplasms
Hepatocellular carcinoma cells cause different responses in expressions of cancer-promoting genes in different cancer-associated fibroblasts.
Neoplasms
HIF-1? promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment.
Neoplasms
High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting.
Neoplasms
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.
Neoplasms
Human lysyl oxidase-like 2.
Neoplasms
Hypermethylated SFRP1, but none of other nine genes "informative" for western countries, is valuable for bladder cancer detection in Mainland China.
Neoplasms
Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts.
Neoplasms
Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells.
Neoplasms
Hypoxia-mediated metastasis.
Neoplasms
Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration.
Neoplasms
Hypoxic tumor microenvironments reduce collagen I fiber density.
Neoplasms
Identification and characterization of the promoter of cancer-related gene LOXL2.
Neoplasms
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 ?e13, in esophageal squamous cell carcinoma.
Neoplasms
Identification of functional hypoxia inducible factor response elements in the human lysyl oxidase gene promoter.
Neoplasms
Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization.
Neoplasms
Identification of LOXL3-associating immune infiltration landscape and prognostic value in hepatocellular carcinoma.
Neoplasms
Identification of the lysyl oxidase gene as target of the antioncogenic transcription factor, IRF-1, and its possible role in tumor suppression.
Neoplasms
Immunohistochemical localization of lysyl oxidase in normal human skin.
Neoplasms
Immunohistochemistry analysis reveals lysyl oxidase-like 3 as a novel prognostic marker for primary melanoma.
Neoplasms
Increased expression of hypoxia-inducible factor-1 alpha and its impact on transcriptional changes and prognosis in malignant tumours of the ocular adnexa.
Neoplasms
Increased Expression of the Matrix-Modifying Enzyme Lysyl Oxidase-Like 2 in Aggressive Hepatocellular Carcinoma with Poor Prognosis.
Neoplasms
Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin ?1.
Neoplasms
Influence of Lysyl oxidase Polymorphisms in Cancer Risk: An Updated Meta-analysis.
Neoplasms
Influences of Tumor Necrosis Factor-? on Lysyl Oxidases and Matrix Metalloproteinases of Injured Anterior Cruciate Ligament and Medial Collateral Ligament Fibroblasts.
Neoplasms
Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases.
Neoplasms
Inhibition of LOXL2 Enhances the Radiosensitivity of Castration-Resistant Prostate Cancer Cells Associated with the Reversal of the EMT Process.
Neoplasms
Inhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models.
Neoplasms
Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix.
Neoplasms
Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited.
Neoplasms
Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression.
Neoplasms
Insights from the in silico structural, functional and phylogenetic characterization of canine lysyl oxidase protein.
Neoplasms
Insilico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors.
Neoplasms
Interactive effect of bisphenol A (BPA) exposure with -22G/C polymorphism in LOX gene on the risk of osteosarcoma.
Neoplasms
Intracellular lysyl oxidase: effect of a specific inhibitor on nuclear mass in proliferating cells.
Neoplasms
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1.
Neoplasms
Involvement of cytoskeleton-associated proteins in the commitment of C3H10T1/2 pluripotent stem cells to adipocyte lineage induced by BMP2/4.
Neoplasms
In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example.
Neoplasms
Ionizing radiation attracts tumor targeting and apoptosis by radiotropic lysyl oxidase traceable nanoparticles.
Neoplasms
Ionizing radiation induces tumor cell lysyl oxidase secretion.
Neoplasms
LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.
Neoplasms
LncRNA LOXL1-AS1 regulates the tumorigenesis and development of lung adenocarcinoma through sponging miR-423-5p and targeting MYBL2.
Neoplasms
Long non-conding RNA LOXL1-AS1 sponges miR-589-5p to up-regulate CBX5 expression in renal cell carcinoma.
Neoplasms
Low extracellular lysyl oxidase expression is associated with poor prognosis in patients with prostate cancer.
Neoplasms
Low Numbers of Vascular Vessels Correlate to Progression in Hormone-Naïve Prostate Carcinomas Undergoing Radical Prostatectomy.
Neoplasms
LOX expression in primary nasopharyngeal carcinoma: correlation with prognostic parameters and outcome.
Neoplasms
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.
Neoplasms
LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis.
Neoplasms
LOXL 2 Promotes The Epithelial-Mesenchymal Transition And Malignant Progression Of Cervical Cancer.
Neoplasms
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Neoplasms
LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2.
Neoplasms
LOXL1 Is Regulated by Integrin ?11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity.
Neoplasms
LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP.
Neoplasms
LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition.
Neoplasms
LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype.
Neoplasms
LOXL2 in cancer: Regulation, downstream effectors and novel roles.
Neoplasms
LOXL2 in epithelial cell plasticity and tumor progression.
Neoplasms
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Neoplasms
LOXL2 Inhibitors and Breast Cancer Progression.
Neoplasms
Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation.
Neoplasms
LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.
Neoplasms
LOXL2 promotes vasculogenic mimicry and tumour aggressiveness in hepatocellular carcinoma.
Neoplasms
LOXL2 status correlates with tumor stage and regulates integrin levels to promote tumor progression in ccRCC.
Neoplasms
LOXL2 upregulates hypoxia?inducible factor?1? signaling through Snail?FBP1 axis in hepatocellular carcinoma cells.
Neoplasms
LOXL2 upregulates phosphorylation of ezrin to promote cytoskeletal reorganization and tumor cell invasion.
Neoplasms
LOXL2 Upregulation in Gliomas Drives Tumorigenicity by Activating Autophagy to Promote TMZ Resistance and Trigger EMT.
Neoplasms
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Neoplasms
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.
Neoplasms
LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells.
Neoplasms
LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma.
Neoplasms
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Neoplasms
LOXL4 is downregulated in hepatocellular carcinoma with a favorable prognosis.
Neoplasms
LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Neoplasms
Lysyl Oxidase (LOX) transcriptionally regulates SNAI2 expression and TIMP4 secretion in human cancers.
Neoplasms
Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells.
Neoplasms
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.
Neoplasms
Lysyl Oxidase and the Tumor Microenvironment.
Neoplasms
Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface.
Neoplasms
Lysyl oxidase expression and inhibition in uveal melanoma.
Neoplasms
Lysyl oxidase expression in bronchogenic carcinoma.
Neoplasms
Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia.
Neoplasms
Lysyl oxidase expression is regulated by the H3K27 demethylase Jmjd3 in tumor-associated M2-like macrophages.
Neoplasms
Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma.
Neoplasms
Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer.
Neoplasms
Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer.
Neoplasms
Lysyl oxidase in cancer inhibition and metastasis.
Neoplasms
Lysyl oxidase in cancer research.
Neoplasms
Lysyl oxidase in colorectal cancer.
Neoplasms
Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness.
Neoplasms
Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.
Neoplasms
Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.
Neoplasms
Lysyl oxidase is associated with increased thrombosis and platelet reactivity.
Neoplasms
Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in ewing sarcoma cells.
Neoplasms
Lysyl oxidase is essential for hypoxia-induced metastasis.
Neoplasms
Lysyl oxidase is induced by cell density-mediated cell cycle suppression via RB-E2F1-HIF-1? axis.
Neoplasms
Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen?induced arthritis.
Neoplasms
Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma.
Neoplasms
Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer.
Neoplasms
Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer.
Neoplasms
Lysyl oxidase like-4 monoclonal antibody demonstrates therapeutic effect against head and neck squamous cell carcinoma cells and xenografts.
Neoplasms
Lysyl oxidase may play a critical role in hypoxia-induced NSCLC cells invasion and migration.
Neoplasms
Lysyl oxidase mediates hypoxia-induced radioresistance in non-small cell lung cancer A549 cells.
Neoplasms
Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Neoplasms
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts.
Neoplasms
Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.
Neoplasms
Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation.
Neoplasms
Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Neoplasms
Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo.
Neoplasms
Lysyl oxidase rs1800449 polymorphism and cancer risk among Asians: evidence from a meta-analysis and a case-control study of colorectal cancer.
Neoplasms
Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis.
Neoplasms
Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
Neoplasms
Lysyl oxidase, cellular senescence and tumor suppression.
Neoplasms
Lysyl Oxidase, Extracellular Matrix Remodeling and Cancer Metastasis.
Neoplasms
Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.
Neoplasms
Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1.
Neoplasms
Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.
Neoplasms
Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin.
Neoplasms
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Neoplasms
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Neoplasms
Lysyl oxidase-like 2 is a regulator of angiogenesis through modulation of endothelial-to-mesenchymal transition.
Neoplasms
Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.
Neoplasms
Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer.
Neoplasms
Lysyl oxidase-like 2 promotes esophageal squamous cell carcinoma cell migration independent of catalytic activity.
Neoplasms
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.
Neoplasms
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Neoplasms
Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.
Neoplasms
Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway.
Neoplasms
Lysyl Oxidase-Like 4 Fosters an Immunosuppressive Microenvironment During Hepatocarcinogenesis.
Neoplasms
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Neoplasms
Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer.
Neoplasms
Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas.
Neoplasms
Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer.
Neoplasms
Lysyl oxidase-like-2 promotes tumour angiogenesis and is a potential therapeutic target in angiogenic tumours.
Neoplasms
Lysyl oxidase: a potential target for cancer therapy.
Neoplasms
Lysyl oxidase: from basic science to future cancer treatment.
Neoplasms
Lysyl Oxidase: Its Diversity in Health and Diseases.
Neoplasms
Lysyl oxidases: a novel multifunctional amine oxidase family.
Neoplasms
Lysyl oxidases: linking structures and immunity in the tumor microenvironment.
Neoplasms
Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures.
Neoplasms
Mass cytometry and transcriptomic profiling reveal body-wide pathology induced by Loxl1 deficiency.
Neoplasms
Matrix stiffness-mediated effects on macrophages polarization and their LOXL2 expression.
Neoplasms
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Neoplasms
Mechanism of irradiation-induced mammary cancer metastasis: A role for SAP-dependent Mkl1 signaling.
Neoplasms
Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts.
Neoplasms
MicroRNAs and the hallmarks of cancer.
Neoplasms
miR-210 promotes lung adenocarcinoma proliferation, migration, and invasion by targeting lysyl oxidase-like 4.
Neoplasms
Molecular Mechanisms and Potential Therapeutic Targets in Incisional Hernia.
Neoplasms
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells.
Neoplasms
Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia.
Neoplasms
Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development.
Neoplasms
Neutrophils expressing lysyl oxidase-like 4 protein are present in colorectal cancer liver metastases resistant to anti-angiogenic therapy.
Neoplasms
NNK, a tobacco-specific carcinogen, inhibits the expression of lysyl oxidase, a tumor suppressor.
Neoplasms
Non-coding RNA LOXL1-AS1 exhibits oncogenic activity in ovarian cancer via regulation of miR-18b-5p/VMA21 axis.
Neoplasms
Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.
Neoplasms
Opening the LOX to bone metastasis: The role of secreted lysyl oxidase in skeletal recurrence of breast cancers.
Neoplasms
Optical molecular imaging of lysyl oxidase activity - detection of active fibrogenesis in human lung tissue.
Neoplasms
Orthotopic non-metastatic and metastatic oral cancer mouse models.
Neoplasms
Over-expression of lysyl oxidase is associated with poor prognosis and response to therapy of patients with lower grade gliomas.
Neoplasms
P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell MDA-MB-231 contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment.
Neoplasms
PACE4 Proteolytically Processes LOXL2 with little impact on its catalytic activity.
Neoplasms
Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study.
Neoplasms
Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis.
Neoplasms
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.
Neoplasms
Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT.
Neoplasms
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Neoplasms
Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study.
Neoplasms
Prognostic and clinicopathological significance of LOXL2 in cancers: A systematic review and meta-analysis.
Neoplasms
Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma.
Neoplasms
Prognostic utility and clinical significance of lysyl oxidase-like 2 protein expression in digestive system cancers.
Neoplasms
Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment.
Neoplasms
Pulsed Electron Paramagnetic Resonance Insights into the Ligand Environment of Copper in Drosophila Lysyl Oxidase.
Neoplasms
Quantification of ?-aminopropionitrile, an inhibitor of lysyl oxidase activity, in plasma and tumor of mice by liquid chromatography tandem mass spectrometry.
Neoplasms
Quantitative assessment of gene methylation in neoplastic and non-neoplastic gastric epithelia using methylation-specific DNA microarray.
Neoplasms
Radiotherapy-Resistant Breast Cancer Cells Enhance Tumor Progression by Enhancing Premetastatic Niche Formation through the HIF-1?-LOX Axis.
Neoplasms
Re: Tumour-Suppressive MicroRNA-29s Directly Regulate LOXL2 Expression and Inhibit Cancer Cell Migration and Invasion in Renal Cell Carcinoma.
Neoplasms
Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2.
Neoplasms
Recognition of lysyl oxidase as a potential predictive biomarker for oral squamous cell carcinoma: an immunohistochemical study.
Neoplasms
Recombinant Human Lysyl Oxidase-like 2 Secreted from Human Embryonic Kidney Cells Displays Complex and Acidic Glycans at All Three N-Linked Glycosylation Sites.
Neoplasms
Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts.
Neoplasms
Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer.
Neoplasms
Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.
Neoplasms
Reduction of LOX- and LOXL2-mRNA expression in head and neck squamous cell carcinomas.
Neoplasms
Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence.
Neoplasms
Regulation of collagen deposition and lysyl oxidase by tumor necrosis factor-alpha in osteoblasts.
Neoplasms
Regulation of Extracellular Matrix Remodeling Proteins by Osteoblasts in Titanium Nanoparticle-Induced Aseptic Loosening Model.
Neoplasms
Regulation of lysyl oxidase expression in THP-1 cell-derived M2-like macrophages.
Neoplasms
Reorganized Collagen in the Tumor Microenvironment of Gastric Cancer and Its Association with Prognosis.
Neoplasms
Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.
Neoplasms
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression.
Neoplasms
Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis.
Neoplasms
Roles of Copper-Binding Proteins in Breast Cancer.
Neoplasms
Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer.
Neoplasms
Salidroside ameliorated hypoxia-induced tumorigenesis of BxPC-3 cells via downregulating hypoxia-inducible factor (HIF)-1? and LOXL2.
Neoplasms
SCUBE3 regulation of early lung cancer angiogenesis and metastatic progression.
Neoplasms
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Neoplasms
Secretory leukocyte protease inhibitor mediates proliferation of human endometrial epithelial cells by positive and negative regulation of growth-associated genes.
Neoplasms
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Neoplasms
Significance of HIF-1? Expression and LOXL-2 Localization in Progression of Oral Squamous Cell Carcinoma.
Neoplasms
Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma.
Neoplasms
Significance of Lysyl oxidase?like 2 gene expression on the epithelial?mesenchymal status of hepatocellular carcinoma.
Neoplasms
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.
Neoplasms
Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma.
Neoplasms
Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway.
Neoplasms
Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors.
Neoplasms
Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma.
Neoplasms
Stromally Derived Lysyl Oxidase Promotes Metastasis of Transforming Growth Factor-?-Deficient Mouse Mammary Carcinomas.
Neoplasms
Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer.
Neoplasms
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer.
Neoplasms
Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours.
Neoplasms
Targeting the lysyl oxidases in tumour desmoplasia.
Neoplasms
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis.
Neoplasms
TGF-?1 promotes linear invadosome formation in hepatocellular carcinoma cells, through DDR1 up-regulation and collagen I cross-linking.
Neoplasms
The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene).
Neoplasms
The Core Promoter and Redox-sensitive Cis-elements as Key Targets for Inactivation of the Lysyl Oxidase Gene by Cadmium.
Neoplasms
The effect of LOXL2 in hepatocellular carcinoma.
Neoplasms
The function and mechanisms of action of LOXL2 in cancer (Review).
Neoplasms
The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Neoplasms
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.
Neoplasms
The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins.
Neoplasms
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
Neoplasms
The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.
Neoplasms
The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
Neoplasms
The pathological significance of LOXL2 in pre-metastatic niche formation of HCC and its related molecular mechanism.
Neoplasms
The potential for LOXL2 as a target for future cancer treatment.
Neoplasms
The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.
Neoplasms
The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells.
Neoplasms
The rationale for targeting the LOX family in cancer.
Neoplasms
The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer.
Neoplasms
The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.
Neoplasms
Three-dimensional decellularized tumor extracellular matrices with different stiffness as bioengineered tumor scaffolds.
Neoplasms
Tumor potential in rat wounds after short- and long-term administration of platelet-rich plasma.
Neoplasms
Tumor suppressive effect of lysyl oxidase proenzyme.
Neoplasms
Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.
Neoplasms
Tumor-secreted LOXL2 Activates Fibroblasts Through FAK Signaling.
Neoplasms
Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma.
Neoplasms
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Neoplasms
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.
Neoplasms
Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma.
Neoplasms
Understanding the molecular mechanism associated with reversal of oral submucous fibrosis targeting hydroxylysine aldehyde-derived collagen cross-links.
Neoplasms
Upregulated LOX and increased collagen content associated with aggressive clinicopathological features and unfavorable outcome in oral squamous cell carcinoma.
Neoplasms
UXT is a LOX-PP Interacting Protein that Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells.
Neoplasms
Vaccination strategy to target lysyl oxidase-like 4 in dendritic cell based immunotherapy for head and neck cancer.
Neoplasms
VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors.
Neoplasms
Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation.
Neoplasms
Wnt signaling and Loxl2 promote aggressive osteosarcoma.
Neoplasms
ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis.
Neoplasms
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Neoplasms
[Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR]
Neoplasms, Glandular and Epithelial
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.
Neoplasms, Squamous Cell
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Neoplastic Cells, Circulating
Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study.
Nephritis, Hereditary
Lysyl oxidase like-2 contributes to renal fibrosis in Col4?3/Alport mice.
Neuroblastoma
LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.
Neuroblastoma
Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis.
Neurodegenerative Diseases
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Nevus
Divergent roles of lysyl oxidase family members in ornithine decarboxylase- and RAS-transformed mouse fibroblasts and human melanoma cells.
Non-alcoholic Fatty Liver Disease
Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice.
Non-alcoholic Fatty Liver Disease
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis.
Obesity
3D Bioprinting of Breast Cancer Models for Drug Resistance Study.
Obesity
Increased aortic stiffness and attenuated lysyl oxidase activity in obesity.
Obesity
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.
Obesity
The lysyl oxidase inhibitor (?-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.
Obesity
The lysyl oxidase inhibitor ?-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats.
Obesity, Morbid
Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea.
Ocular Hypertension
Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior.
Odontogenic Tumors
Identification of the involvement of LOXL4 in generation of keratocystic odontogenic tumors by RNA-Seq analysis.
Optic Nerve Glioma
Increased Tissue Stiffness in Tumors from Mice with Neurofibromatosis-1 Optic Glioma.
Oral Submucous Fibrosis
Association between lysyl oxidase polymorphisms and oral submucous fibrosis in older male areca chewers.
Oral Submucous Fibrosis
Comparative Evaluation of role of Lysyl oxidase gene (LOXG473A) expression in pathogenesis and malignant transformation of Oral Submucous Fibrosis.
Oral Submucous Fibrosis
Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis.
Oral Submucous Fibrosis
Increased lysyl oxidase activity in fibroblasts cultured from oral submucous fibrosis associated with betel nut chewing in Taiwan.
Oral Submucous Fibrosis
Molecular screening of lysyl oxidase G473A polymorphism in oral submucous fibrosis.
Oral Submucous Fibrosis
The upregulation of lysyl oxidase in oral submucous fibrosis and squamous cell carcinoma.
Osteoarthritis
Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis.
Osteoarthritis
Identification of functional hypoxia inducible factor response elements in the human lysyl oxidase gene promoter.
Osteoarthritis
Leptin promotes apoptosis and inhibits autophagy of chondrocytes through upregulating lysyl oxidase-like 3 during osteoarthritis pathogenesis.
Osteoarthritis
LncRNA LOXL1-AS1 is transcriptionally activated by JUND and contributes to osteoarthritis progression via targeting the miR-423-5p/KDM5C axis.
Osteoarthritis
LOXL2 as a protective in osteoarthritis cartilage.
Osteoarthritis
LOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling.
Osteoarthritis
Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
Osteoarthritis, Knee
Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
Osteogenesis Imperfecta
An unusual pattern of peptide-bound lysine metabolism in collagen from an infant with lethal perinatal osteogenesis imperfecta.
Osteogenesis Imperfecta
Defects in the biochemistry of collagen in diseases of connective tissue.
Osteogenesis Imperfecta
Lysyl oxidase in osteogenesis imperfecta and Marfan's syndrome.
Osteoporosis
'Mysterious' moose disease in Sweden. Similarities to copper deficiency and/or molybdenosis in cattle and sheep. Biochemical background of clinical signs and organ lesions.
Osteoporosis
A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia.
Osteoporosis
Pamidronate treatment improves bone mineral density in children with Menkes disease.
Osteosarcoma
A novel human lysyl oxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain.
Osteosarcoma
Expression of lysyl oxidase in human osteosarcoma and its clinical significance: A tumor suppressive role of LOX in human osteosarcoma cells.
Osteosarcoma
Functional analysis of the promoter and first intron of the human lysyl oxidase gene.
Osteosarcoma
Interactive effect of bisphenol A (BPA) exposure with -22G/C polymorphism in LOX gene on the risk of osteosarcoma.
Osteosarcoma
Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin.
Osteosarcoma
Lysyl oxidase polymorphisms and susceptibility to osteosarcoma.
Osteosarcoma
Molecular events that contribute to lysyl oxidase enzyme activity and insoluble collagen accumulation in osteosarcoma cell clones.
Osteosarcoma
Wnt signaling and Loxl2 promote aggressive osteosarcoma.
Ovarian Neoplasms
Association between Lysyl Oxidase G473A Polymorphism and Ovarian Cancer in the Han Chinese Population.
Ovarian Neoplasms
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.
Ovarian Neoplasms
Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Ovarian Cancer.
Ovarian Neoplasms
The plasma peptides of ovarian cancer.
Ovarian Neoplasms
The prognostic value of the lysyl oxidase family in ovarian cancer.
Ovarian Neoplasms
Uncovering the role of nuclear Lysyl oxidase (LOX) in advanced high grade serous ovarian cancer.
Pancreatic Neoplasms
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Pancreatic Neoplasms
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Pancreatic Neoplasms
Emerging role of LOXL2 in the promotion of pancreas cancer metastasis.
Pancreatic Neoplasms
Functional analysis of LOXL2 in pancreatic carcinoma.
Pancreatic Neoplasms
Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Pancreatic Neoplasms
miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2.
Pancreatic Neoplasms
Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.
Pancreatic Neoplasms
Salidroside ameliorated hypoxia-induced tumorigenesis of BxPC-3 cells via downregulating hypoxia-inducible factor (HIF)-1? and LOXL2.
Paralysis
Embryo movements regulate tendon mechanical property development.
Pelvic Floor Disorders
Bladder and urethral function in pelvic organ prolapsed lysyl oxidase like-1 knockout mice.
Perinatal Death
Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice.
Peritoneal Fibrosis
Targeting lysyl oxidase reduces peritoneal fibrosis.
Polycystic Ovary Syndrome
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Polycystic Ovary Syndrome
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
Potassium Deficiency
Copper response to rheumatoid arthritis.
Pre-Eclampsia
Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-?/collagen pathway in preeclampsia.
Pre-Eclampsia
Upregulation of miR-29a suppressed the migration and invasion of trophoblasts by directly targeting LOXL2 in preeclampsia.
Priapism
Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Primary Myelofibrosis
Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies.
Primary Myelofibrosis
Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase.
Primary Myelofibrosis
Lysyl oxidase inhibition in primary myelofibrosis: A renewed strategy.
Primary Myelofibrosis
Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection.
Primary Myelofibrosis
Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice.
Primary Myelofibrosis
Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis.
procollagen-lysine 5-dioxygenase deficiency
Defects in the biochemistry of collagen in diseases of connective tissue.
Progeria
Arterial stiffness and cardiac dysfunction in Hutchinson-Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase.
Prostatic Neoplasms
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.
Prostatic Neoplasms
Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score.
Prostatic Neoplasms
Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide.
Prostatic Neoplasms
Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways.
Prostatic Neoplasms
High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting.
Prostatic Neoplasms
Hypoxia and Prostate Cancer Aggressiveness: A Tale With Many Endings.
Prostatic Neoplasms
Inhibition of LOXL2 Enhances the Radiosensitivity of Castration-Resistant Prostate Cancer Cells Associated with the Reversal of the EMT Process.
Prostatic Neoplasms
Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer.
Prostatic Neoplasms
Low extracellular lysyl oxidase expression is associated with poor prognosis in patients with prostate cancer.
Prostatic Neoplasms
LOXL1-AS1 predicts poor prognosis and promotes cell proliferation, migration, and invasion in osteosarcoma.
Prostatic Neoplasms
Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.
Prostatic Neoplasms
Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Prostatic Neoplasms
Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo.
Prostatic Neoplasms
Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer.
Prostatic Neoplasms
Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.
Prostatic Neoplasms
[Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR]
Protein Deficiency
Hepatic collagen content and lysyl oxidase activity in rats fed a low protein-ethanol diet.
Protein Deficiency
Lysyl Oxidase-Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-?1-induced Pulmonary Fibrosis.
protein-lysine 6-oxidase deficiency
A skeletal and connective tissue disorder associated with lysyl oxidase deficiency and abnormal copper metabolism.
protein-lysine 6-oxidase deficiency
Aortic elastin abnormalities in osteogenesis imperfecta type II.
protein-lysine 6-oxidase deficiency
Congenital cutis laxa and lysyl oxidase deficiency.
protein-lysine 6-oxidase deficiency
Downregulation of lysyl oxidase in cadmium-resistant fibroblasts.
protein-lysine 6-oxidase deficiency
Ehlers-Danlos type V (X-linked form): a lysyl oxidase deficiency.
protein-lysine 6-oxidase deficiency
Failure of elastic fiber homeostasis leads to pelvic floor disorders.
protein-lysine 6-oxidase deficiency
Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice.
protein-lysine 6-oxidase deficiency
Increased frequency of congenital heart defects in Menkes disease.
protein-lysine 6-oxidase deficiency
LOXL1 Deficiency in the Lamina Cribrosa as Candidate Susceptibility Factor for a Pseudoexfoliation-Specific Risk of Glaucoma.
protein-lysine 6-oxidase deficiency
LOXL1 deficiency negatively impacts the biomechanical properties of the mouse vagina and supportive tissues.
protein-lysine 6-oxidase deficiency
LOXL3 novel mutation causing a rare form of autosomal recessive Stickler syndrome.
protein-lysine 6-oxidase deficiency
Lysyl oxidase deficiency in Ehlers-Danlos syndrome type V.
protein-lysine 6-oxidase deficiency
Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema.
protein-lysine 6-oxidase deficiency
Lysyl oxidase deficiency: a new cause of human arterial dissection.
protein-lysine 6-oxidase deficiency
Mass cytometry and transcriptomic profiling reveal body-wide pathology induced by Loxl1 deficiency.
protein-lysine 6-oxidase deficiency
Role of lysyl oxidase like 1 in regulation of postpartum connective tissue metabolism in the mouse vagina.
protein-lysine 6-oxidase deficiency
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
protein-lysine 6-oxidase deficiency
X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity.
Pterygium
Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review.
Pulmonary Arterial Hypertension
Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension.
Pulmonary Disease, Chronic Obstructive
[Bone quality in COPD.]
Pulmonary Fibrosis
Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis.
Pulmonary Fibrosis
Hypoxia-inducible factor-1? regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase.
Pulmonary Fibrosis
LOX/LOXL in pulmonary fibrosis: potential therapeutic targets.
Pulmonary Fibrosis
LOXL2, a copper-dependent monoamine oxidase, activates lung fibroblasts through the TGF-?/Smad pathway.
Pulmonary Fibrosis
Lysyl oxidase promotes epithelial-to-mesenchymal transition during paraquat-induced pulmonary fibrosis.
Pulmonary Fibrosis
Lysyl Oxidase-Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-?1-induced Pulmonary Fibrosis.
Pulmonary Fibrosis
N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats.
Pulmonary Fibrosis
The copper chelator tetrathiomolybdate regressed bleomycin-induced pulmonary fibrosis in mice, by reducing lysyl oxidase expressions.
Pulmonary Fibrosis
The serum level and significance of lysyl oxidase-like 2 in patients with rheumatoid arthritis-associated interstitial lung disease.
Rectal Neoplasms
Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.
Rectal Neoplasms
Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.
Renal Insufficiency, Chronic
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.
Renal Insufficiency, Chronic
[Bone quality].
Respiratory Distress Syndrome
Significance of nuclear LOXL2 inhibition in fibroblasts and myofibroblasts in the fibrotic process of acute respiratory distress syndrome.
Retinal Detachment
Effects of Lysyl Oxidase Genetic Variants on the Susceptibility to Rhegmatogenous Retinal Detachment and Proliferative Vitreoretinopathy.
Retinal Detachment
Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment.
Retinal Vein Occlusion
Analysis of LOXL1 gene variants in Japanese patients with branch retinal vein occlusion.
Retinal Vein Occlusion
Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits.
Retinoblastoma
Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells.
Rhabdomyosarcoma, Alveolar
LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.
Sarcoma
Deficient production of lysyl oxidase in cultures of malignantly transformed human cells.
Sarcoma, Ewing
Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in ewing sarcoma cells.
Schistosomiasis
Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis.
Scleroderma, Localized
Increased expression of lysyl oxidase in skin with scleroderma.
Scleroderma, Localized
[The diagnostic importance of research on the lysyl oxidase activity in children with circumscribed scleroderma]
Scleroderma, Systemic
Brief report: lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis.
Scleroderma, Systemic
Increased expression of lysyl oxidase in skin with scleroderma.
Scleroderma, Systemic
Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis.
Scleroderma, Systemic
Lysyl Oxidase in Systemic Sclerosis: Getting Under the Skin.
Scleroderma, Systemic
Systemic Sclerosis Dermal Fibroblasts Induce Cutaneous Fibrosis Through LOXL4: New Evidence from 3D Skin-like Tissues.
Scoliosis
Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.
Scoliosis
Elevated hair copper level in idiopathic scoliosis: preliminary observations.
Scoliosis
Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations.
Skin Diseases
[The diagnostic importance of research on the lysyl oxidase activity in children with circumscribed scleroderma]
Sleep Apnea, Obstructive
Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea.
Small Cell Lung Carcinoma
MiR-504 inhibits cell proliferation and invasion by targeting LOXL2 in non small cell lung cancer.
Spasm
Copper metabolism in mottled mouse mutants: copper therapy of brindled (Mobr) mice.
Spinal Cord Injuries
Beta-aminopropionitrile treatment can accelerate recovery of mice after spinal cord injury.
Squamous Cell Carcinoma of Head and Neck
A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma.
Squamous Cell Carcinoma of Head and Neck
LOXL4 is a selectively expressed candidate diagnostic antigen in head and neck cancer.
Squamous Cell Carcinoma of Head and Neck
Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC).
Squamous Cell Carcinoma of Head and Neck
Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer.
Squamous Cell Carcinoma of Head and Neck
Lysyl oxidase like-4 monoclonal antibody demonstrates therapeutic effect against head and neck squamous cell carcinoma cells and xenografts.
Squamous Cell Carcinoma of Head and Neck
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Squamous Cell Carcinoma of Head and Neck
Overexpression of a novel lysyl oxidase-like gene in human head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Recognition of lysyl oxidase as a potential predictive biomarker for oral squamous cell carcinoma: an immunohistochemical study.
Squamous Cell Carcinoma of Head and Neck
Reduction of LOX- and LOXL2-mRNA expression in head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Significance of HIF-1? Expression and LOXL-2 Localization in Progression of Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Starvation
Changes in lung lysyl oxidase activity in streptozotocin-diabetes and in starvation.
Starvation
Verteporfin as a Medical Treatment in Peyronie's Disease.
Stomach Neoplasms
A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.
Stomach Neoplasms
Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.
Stomach Neoplasms
Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells.
Stomach Neoplasms
LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.
Stomach Neoplasms
Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells.
Stomach Neoplasms
Lysyl oxidase and hypoxia-inducible factor 1?: biomarkers of gastric cancer.
Stomach Neoplasms
Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.
Stomach Neoplasms
Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.
Stomach Neoplasms
Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia.
Stomach Neoplasms
Lysyl oxidase isoforms in gastric cancer.
Stomach Neoplasms
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts.
Stomach Neoplasms
Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.
Stomach Neoplasms
Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway.
Stomach Neoplasms
Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT.
Stomach Neoplasms
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Stomach Neoplasms
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.
Stomach Neoplasms
Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma.
Stomach Neoplasms
[Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro].
Stomach Neoplasms
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Thrombosis
Biomechanical consequences of compromised elastic fiber integrity and matrix cross-linking on abdominal aortic aneurysmal enlargement.
Thrombosis
Emerging Factors Implicated in Fibrotic Organ-Associated Thrombosis: The Case of Two Organs.
Thrombosis
Lysyl oxidase is associated with increased thrombosis and platelet reactivity.
Thyroid Neoplasms
GINS2 promotes cell proliferation and inhibits cell apoptosis in thyroid cancer by regulating CITED2 and LOXL2.
Thyroid Neoplasms
Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness.
Tracheobronchomegaly
Neonatal deaths and pulmonary dysplasia due to D-penicillamine in the rat.
Tremor
Copper metabolism in mottled mouse mutants: copper therapy of brindled (Mobr) mice.
Triple Negative Breast Neoplasms
Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression.
Triple Negative Breast Neoplasms
LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells.
Triple Negative Breast Neoplasms
LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Lysyl oxidase engineered lipid nanovesicles for the treatment of triple negative breast cancer.
Triple Negative Breast Neoplasms
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer.
Urinary Bladder Neoplasms
Hypermethylated SFRP1, but none of other nine genes "informative" for western countries, is valuable for bladder cancer detection in Mainland China.
Urinary Bladder Neoplasms
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Urinary Bladder Neoplasms
Lysyl oxidase family members in urological tumorigenesis and fibrosis.
Urinary Bladder Neoplasms
miR-193a-3p regulates the multi-drug resistance of bladder cancer by targeting the LOXL4 gene and the Oxidative Stress pathway.
Urinary Incontinence
Expression and significance of lysyl oxidase-like 1 and fibulin-5 in the cardinal ligament tissue of patients with pelvic floor dysfunction.
Urinary Incontinence
TT polymorphism in rs2165241 and rs1048661 region in lysyl oxidase like-1 gene may have a role in stress urinary incontinence physiopathology.
Uterine Cervical Neoplasms
Circular RNA circ_0000228 promotes the malignancy of cervical cancer via microRNA-195-5p/ lysyl oxidase-like protein 2 axis.
Uterine Cervical Neoplasms
Inactivation of lysyl oxidase by ?-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells.
Uterine Cervical Neoplasms
LOXL 2 Promotes The Epithelial-Mesenchymal Transition And Malignant Progression Of Cervical Cancer.
Uterine Cervical Neoplasms
Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer.
Vascular Diseases
LOXL1 Gene Sequence Variants and Vascular Disease in Exfoliation Syndrome and Exfoliative Glaucoma.
Vascular Diseases
PACE4 Proteolytically Processes LOXL2 with little impact on its catalytic activity.
Vascular System Injuries
Elastic tissue disruption is a major pathogenic factor to human vascular disease.
Vascular System Injuries
Lysyl oxidase expression in a rat model of arterial balloon injury.
Vascular System Injuries
Transforming growth factor-beta 1 increases lysyl oxidase enzyme activity and mRNA in rat aortic smooth muscle cells.
Venous Insufficiency
Down-regulation of lysyl oxydase-like in aging and venous insufficiency.
Vertigo
A novel genetic variant associated with benign paroxysmal positional vertigo within the LOXL1.
Vitamin B 6 Deficiency
The effect of pyridoxine deficiency on lysyl oxidase activity in the chick.
Vitamin D Deficiency
Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation.
Vitreoretinopathy, Proliferative
Effects of Lysyl Oxidase Genetic Variants on the Susceptibility to Rhegmatogenous Retinal Detachment and Proliferative Vitreoretinopathy.
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