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Information on EC 1.4.1.2 - glutamate dehydrogenase
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1.4.1.2 glutamate dehydrogenaseSpecify your search results
Word Map
- 1.4.1.2
- ammonia
- aminotransferase
- giardia
-
deamination
- dehydrogenases
- malate
- alpha-ketoglutarate
- clostridium
- difficile
-
assemblage
- transaminase
- succinate
- duodenalis
- adp
- 2-oxoglutarate
- toxin
- nitrate
-
stool
- glutaminase
-
zoonotic
- isocitrate
-
immunoassay
-
fecal
- tpi
-
transamination
-
multilocus
-
toxigenic
- neurospora
- hyperinsulinism
- triose
- hypoglycemia
- oxaloacetate
-
nadp-dependent
- bilirubin
-
hexameric
-
hyperammonemia
- giardiasis
-
triosephosphate
- l-leucine
- cryptosporidium
- no3
- aminooxyacetate
- intestinalis
-
ribotype
-
quinoproteins
- gamma-glutamyltransferase
-
glutaminolysis
- diazoxide
- degradation
- agriculture
- biotechnology
- gaba-t
- drug development
- medicine
- molecular biology
-
pancreatectomy
- analysis
- food industry
- energy production
- diagnostics
- synthesis
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
glutamate dehydrogenase, gdh, glud1, hgdh1, glutamic dehydrogenase, nad-gdh, l-glutamate dehydrogenase, nad-dependent glutamate dehydrogenase, nadh-gdh, glutamic acid dehydrogenase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
dehydrogenase, glutamate
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GDH
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glutamate dehydrogenase (NAD)
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glutamate oxidoreductase
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glutamic acid dehydrogenase
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glutamic dehydrogenase
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L-glutamate dehydrogenase
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NAD-dependent glutamate dehydrogenase
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NAD-dependent glutamic dehydrogenase
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NAD-GDH
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NAD-glutamate dehydrogenase
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NAD-linked glutamate dehydrogenase
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NAD-linked glutamic dehydrogenase
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NAD-specific glutamate dehydrogenase
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NAD-specific glutamic dehydrogenase
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NAD:glutamate oxidoreductase
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NADH-dependent glutamate dehydrogenase
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NADH-linked glutamate dehydrogenase
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Surface-associated protein PGAG1
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
redox reaction
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oxidation
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reduction
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reductive amination
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PATHWAY SOURCE
PATHWAYS
KEGG
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-, -, -, -, -, -, -
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SYSTEMATIC NAME
IUBMB Comments
L-glutamate:NAD+ oxidoreductase (deaminating)
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CAS REGISTRY NUMBER
COMMENTARY
9001-46-1
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
3-hydroxy-2-methylbutyryl-coa dehydrogenase deficiency
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.
3-hydroxy-2-methylbutyryl-coa dehydrogenase deficiency
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
3-hydroxyacyl-coa dehydrogenase deficiency
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.
Abscess
Protease-Mediated Growth of Staphylococcus aureus on Host Proteins Is opp3 Dependent.
Abscess
[Application of serum glutamic dehydrogenase for the diagnosis of hepatic carcinoma and abscess and for the evaluation of their treatment (author's transl)]
Acidosis
Activation of oxoglutarate dehydrogenase in the kidney in response to acute acidosis.
Acidosis
Adaptation of renal tricarboxylic acid cycle metabolism to various acid-base states: study with [3-13C,5-15N]glutamine.
Acidosis
Biochemical and histocytochemical studies on response of ammonia-producing enzymes for nh4cl-induced acidosis.
Acidosis
Changes in the profile of liver enzymes in newborn calves induced by experimental, subclinical acidosis in pregnant cows and osmotic diarrhoea.
Acidosis
Effect of altered acid-base balance and of various agonists on levels of renal glutamate dehydrogenase mRNA.
Acidosis
Evidence of activation of the renal glutamate dehydrogenase pathway in intact acidotic dogs.
Acidosis
Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.
Acidosis
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
Acidosis
Metabolism of glutamine and glutamate by rat renal tubules. Study with 15N and gas chromatography-mass spectrometry.
Acidosis
Plasma amino acid concentrations and mRNA expression of components related to protein degradation in lambs with nutritionally induced metabolic acidosis.
Acidosis
Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks.
Acidosis
Renal metabolite concentrations and the activities of glutaminase and glutamate dehydrogenase during recovery from metabolic acidosis in the rat.
Acidosis
The kidney of chicken adapts to chronic metabolic acidosis: in vivo and in vitro studies.
Acquired Immunodeficiency Syndrome
Chronic subclinical ovine fascioliasis: plasma glutamate dehydrogenase, gamma-glutamyl transpeptidase and aspartate aminotransferase activities and their significance as diagnostic aids.
Acrodynia
gdhB, a gene encoding a second quinoprotein glucose dehydrogenase in Pantoea citrea, is required for pink disease of pineapple.
Acrodynia
Identification and characterization of a Pantoea citrea gene encoding glucose dehydrogenase that is essential for causing pink disease of pineapple.
Adenocarcinoma
Hyperthermia potentiates cisplatin cytotoxicity and negative effects on mitochondrial functions in OVCAR-3 cells.
Adrenocortical Hyperfunction
Effect of serum storage, anti-inflammatory oral doses of prednisone, and spontaneous hyperadrenocorticism on serum glutamate dehydrogenase activity in dogs.
Alzheimer Disease
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Alzheimer Disease
Glutamate metabolizing enzymes in prefrontal cortex of Alzheimer's disease patients.
Alzheimer Disease
Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients.
Alzheimer Disease
Lymphocyte glutamate dehydrogenase activity in normal aging and neurological diseases.
Alzheimer Disease
Plasma concentrations of glutamate and its metabolites in patients with Alzheimer's disease.
Alzheimer Disease
[Impaired cerebral glutamate metabolism in mental diseases (Alzheimer's disease, schizophrenia]
Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis: glutamate dehydrogenase and transmitter amino acids in the spinal cord.
Amyotrophic Lateral Sclerosis
Glutamate dehydrogenase activity in amyotrophic lateral sclerosis.
Anemia
NTP Toxicology and Carcinogenesis Studies of Chloroprene (CAS No. 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).
Arthritis
Oxidative state and oxidative metabolism of the heart from rats with adjuvant-induced arthritis.
Astrocytoma
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness.
Asymptomatic Infections
Detection of Clostridium difficile in Feces of Asymptomatic Patients Admitted to the Hospital.
Ataxia
Cryo-EM structures of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture.
Ataxia
Leukocyte glutamate dehydrogenase and CSF amino acids in late onset ataxias.
Basal Ganglia Diseases
Degenerative neurological disorders associated with deficiency of glutamate dehydrogenase.
beta-Thalassemia
Glycerol-3-phosphate dehydrogenase activity in the red cells of patients with thalassemia.
Brain Concussion
[Changes in the activities of oxidoreductases, content of malondialdehyde and medium weight molecules in the blood of patients with craniocerebral injuries of different severity]
Brain Diseases, Metabolic
Differential effects of fatty acyl coenzyme A derivatives on citrate synthase and glutamate dehydrogenase.
Brain Ischemia
Glutamate dehydrogenase as a neuroprotective target against brain ischemia and reperfusion.
Brain Neoplasms
[Activities of glutamate dehydrogenase and aspartate aminotransferase in human brain tumors]
Breast Neoplasms
Blood and Tissue Enzymatic Activities of GDH and LDH, Index of Glutathione, and Oxidative Stress among Breast Cancer Patients Attending Referral Hospitals of Addis Ababa, Ethiopia: Hospital-Based Comparative Cross-Sectional Study.
Breast Neoplasms
Expression of glutamine metabolism-related proteins according to molecular subtype of breast cancer.
Breast Neoplasms
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Carcinogenesis
Effects of low-dose radiation on glutamate dehydrogenase activity in tissues of rats with transplanted Guerin's carcinoma.
Carcinogenesis
Glutaminolysis and glycolysis regulation by troglitazone in breast cancer cells: relationship to mitochondrial membrane potential.
Carcinoma
Effects of low-dose radiation on glutamate dehydrogenase activity in tissues of rats with transplanted Guerin's carcinoma.
Carcinoma
Flow-cytometric determination of dehydrogenase activities in primary human gastrointestinal tumor cell lines.
Carcinoma
[Application of serum glutamic dehydrogenase for the diagnosis of hepatic carcinoma and abscess and for the evaluation of their treatment (author's transl)]
Carcinoma
[Glutamate dehydrogenase from human liver. VI. Glutamate dehydrogenase in primary liver cell carcinomas]
Carcinoma, Ehrlich Tumor
Changes in enzyme pattern of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content.
Carcinoma, Ehrlich Tumor
Enzyme activities of six different dehydrogenases in Ehrlich ascites cells measured by flow cytometry.
Carcinoma, Hepatocellular
Characterization of glutamate dehydrogenase isoproteins purified from the cerebellum of normal subjects and patients with degenerative neurological disorders, and from human neoplastic cell lines.
Carcinoma, Hepatocellular
Effects of glutamate dehydrogenase, choline oxidase, and glucose-6-phosphatase on 67Ga accumulation in lysosome.
Carcinoma, Hepatocellular
Glutamate dehydrogenase activity related to histopathological grade of hepatocellular carcinoma in man.
Carcinoma, Hepatocellular
Glutamate dehydrogenase and alkaline phosphatase as very early predictors of hepatocellular carcinoma recurrence after liver transplantation.
Carcinoma, Hepatocellular
Proceedings: Grade of histological differentiation, glutamate dehydrogenase activity and alphafetoprotein production in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Serum level of ornithine carbamoyltransferase is influenced by the state of Kupffer cells.
Carcinoma, Hepatocellular
The comparative enzymology and cell origin of rat hepatomas. II. Glutamate dehydrogenase, choline oxidase, and glucose-6-phosphatase.
Carcinoma, Hepatocellular
[Evaluation of serum glutamic dehydrogenase activity in the diagnosis and treatment of hepatocellular carcinoma and liver metastasis]
Carcinoma, Hepatocellular
[Glutamate dehydrogenase from human liver. VI. Glutamate dehydrogenase in primary liver cell carcinomas]
Cerebellar Ataxia
Glutamate dehydrogenase (GDH) deficiency in different types of progressive hereditary cerebellar ataxia.
Cerebellar Ataxia
Leukocyte glutamate dehydrogenase and CSF amino acids in late onset ataxias.
Chagas Disease
Comparative study of enzymes in testes and ovaries from adult Dipetalogaster maximus (Uhler) and triatoma infestans (Klug) (Hemiptera: Reduviidae). correlation with fine structural organization.
Cholangiocarcinoma
Expression and prognostic value of glutamate dehydrogenase in extrahepatic cholangiocarcinoma patients.
Cholestasis
Activities of APh, gamma-GT, GlDH and GPT and bile acid concentrations in serum after bile duct obstruction and cycloheximide in the rat.
Clostridium Infections
Algorithm combining toxin immunoassay and stool culture for diagnosis of Clostridium difficile infection.
Clostridium Infections
Clinical significance of a positive Clostridioides difficile glutamate dehydrogenase test on the outcomes of hospitalized older patients.
Clostridium Infections
Clostridium difficile infection diagnostics - evaluation of the C. DIFF Quik Chek Complete assay, a rapid enzyme immunoassay for detection of toxigenic C. difficile in clinical stool samples.
Clostridium Infections
Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A/B testing on stool samples.
Clostridium Infections
Diagnostic test accuracy of glutamate dehydrogenase for Clostridium difficile: Systematic review and meta-analysis.
Clostridium Infections
Evaluation of a rapid membrane enzyme immunoassay for the simultaneous detection of glutamate dehydrogenase and toxin for the diagnosis of Clostridium difficile infection.
Clostridium Infections
Evaluation of a simultaneous detection kit for the glutamate dehydrogenase antigen and toxin A/B in feces for diagnosis of Clostridium difficile infection.
Clostridium Infections
Evaluation of risk factors for Clostridium difficile infection based on immunochromatography testing and toxigenic culture assay.
Clostridium Infections
Glutamate dehydrogenase for laboratory diagnosis of Clostridium difficile infection.
Clostridium Infections
In Vitro Selection of Circular DNA Aptamers for Biosensing Applications.
Clostridium Infections
Laboratory diagnosis of clostridium difficile infection. An evaluation of tests for faecal toxin, glutamate dehydrogenase, lactoferrin and toxigenic culture in the diagnostic laboratory.
Clostridium Infections
Simultaneous Detection of Clostridioides difficile Glutamate Dehydrogenase and Toxin A/B: Comparison of the C. DIFF QUIK CHEK COMPLETE and RIDASCREEN Assays.
Clostridium Infections
The Role of Glutamate Dehydrogenase (GDH) Testing Assay in the Diagnosis of Clostridium difficile Infections: A High Sensitive Screening Test and an Essential Step in the Proposed Laboratory Diagnosis Workflow for Developing Countries like China.
Coccidiosis
[Alteration of enzyme activities in serum of Eimeria stiedai infected rabbits (author's transl)]
Coinfection
Giardia and Cryptosporidium infections in Danish cats: risk factors and zoonotic potential.
Coinfection
High genetic polymorphism among Giardia duodenalis isolates from Sahrawi children.
Coinfection
Multiple-subgenotype infections of Giardia intestinalis detected in Palestinian clinical cases using a subcloning approach.
Coinfection
Prevalence and mulilocus genotypes of Giardia duodenalis infecting pigs in Ogun state, Nigeria.
Coinfection
Subclass profile of specific IgG antibodies in rats challenged during acute and chronic primary infection with Fasciola hepatica.
Colorectal Neoplasms
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.
Colorectal Neoplasms
Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.
Coma
Acute metabolic effects of ammonia on the enzymes of glutamate metabolism in isolated astroglial cells.
Coma
Effect of total hepatectomy on selected cerebral substrates and enzymes of the glycolytic pathways and Krebs cycle.
Communicable Diseases
Performance of laboratory tests for detection for Clostridioides difficile: A multicenter prospective study in Japan.
Congenital Hyperinsulinism
A Japanese case of congenital hyperinsulinism with hyperammonemia due to a mutation in glutamate dehydrogenase (GLUD1) gene.
Congenital Hyperinsulinism
Biochemical evaluation of an infant with hypoglycemia resulting from a novel de novo mutation of the GLUD1 gene and hyperinsulinism-hyperammonemia syndrome.
Congenital Hyperinsulinism
Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism.
Congenital Hyperinsulinism
Clinical and Molecular Spectrum of Glutamate Dehydrogenase Gene Defects in 26 Chinese Congenital Hyperinsulinemia Patients.
Congenital Hyperinsulinism
Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro.
Congenital Hyperinsulinism
Glutaminolysis and insulin secretion: from bedside to bench and back.
Congenital Hyperinsulinism
Hyperinsulinism in infancy and childhood: when an insulin level is not always enough.
Congenital Hyperinsulinism
Hyperinsulinism-hyperammonemia syndrome: a de novo mutation of the GLUD1 gene in twins and a review of the literature.
Congenital Hyperinsulinism
Hyperinsulinism/hyperammonemia syndrome: insights into the regulatory role of glutamate dehydrogenase in ammonia metabolism.
Congenital Hyperinsulinism
Mechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinism.
Congenital Hyperinsulinism
Mechanisms of Disease: advances in diagnosis and treatment of hyperinsulinism in neonates.
Congenital Hyperinsulinism
Molecular characterisation of glutamate dehydrogenase gene defects in Japanese patients with congenital hyperinsulinism/hyperammonaemia.
Congenital Hyperinsulinism
Mutational analysis of ABCC8, KCNJ11, GLUD1, HNF4A and GCK genes in 30 Chinese patients with congenital hyperinsulinism.
Congenital Hyperinsulinism
Neurological aspects of hyperinsulinism-hyperammonaemia syndrome.
Congenital Hyperinsulinism
Spectrum of glutamate dehydrogenase mutations in Japanese patients with congenital hyperinsulinism and hyperammonemia syndrome.
Congenital Hyperinsulinism
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase.
Congenital Hyperinsulinism
[ABCC8, KCNJ11 and GLUD1 gene mutation analysis in congenital hyperinsulinism pedigree].
Congenital Hyperinsulinism
[Hyperinsulinism in infancy and childhood: when an insulin level is not always enough.]
Congenital Hyperinsulinism
[Mutation analysis of the GLUD1 gene in patients with glutamate dehydrogenase congenital hyperinsulinism.]
Cystic Fibrosis
Timing and sequence of differentiation of embryonic rat hepatocytes along the biliary epithelial lineage.
Cysts
A natural zoonotic giardiasis: Infection of a child via Giardia cysts in pet chinchilla droppings.
Cysts
Comparison of two target genes for detection and genotyping of Giardia lamblia in human feces by PCR and PCR-restriction fragment length polymorphism.
Cysts
Cryptosporidium and Giardia in Danish organic pig farms: Seasonal and age-related variation in prevalence, infection intensity and species/genotypes.
Cysts
Discrimination of all genotypes of Giardia duodenalis at the glutamate dehydrogenase locus using PCR-RFLP.
Cysts
Giardia lamblia subtypes and their relationship with clinical symptoms in patients with giardiasis.
Cysts
Improved sensitivity of PCR amplification of glutamate dehydrogenase gene for detection and genotyping of Giardia duodenalis in stool specimen.
Cysts
Improvement in cyst recovery and molecular detection of Giardia duodenalis from stool samples.
Cysts
Intestinal parasites and genotyping of Giardia duodenalis in children: first report of genotype B in isolates from human clinical samples in Mexico.
Cysts
Molecular characterisation of Giardia isolates from clinical infections following a waterborne outbreak.
Cysts
Molecular identification of Giardia duodenalis isolates from humans, dogs, cats and cattle from the state of São Paulo, Brazil, by sequence analysis of fragments of glutamate dehydrogenase (gdh) coding gene.
Cysts
Multilocus sequence typing of canine Giardia duodenalis from South Eastern European countries.
Cysts
Performance of glutamate dehydrogenase and triose phosphate isomerase genes in the analysis of genotypic variability of isolates of Giardia duodenalis from livestocks.
Cysts
Quantification of viable Giardia cysts and Cryptosporidium oocysts in wastewater using propidium monoazide quantitative real-time PCR.
Cysts
Sarcocystis fusiformis: some protein metabolic enzymes in various fractions of sarcocysts of buffalo (Bubalus bubalis).
Cysts
Synthesis of pyruvate: ferredoxin oxidoreductase and alcohol dehydrogenase E enzymes during Giardia intestinalis excystation.
Cysts
The mixed AII and BIII genotypes of human Giardia lamblia isolates circulating in Mazandaran Province, northern Iran.
Cysts
Understanding Giardia infections among rural communities using the one health approach.
Cysts
[Comparison of methods of DNA extraction from Giardia spp. measured by conventional PCR].
Dehydration
Ammonium metabolism in Selaginella bryopteris in response to dehydration-rehydration and characterisation of desiccation tolerant, thermostable, cytosolic glutamine synthetase from plant.
Dehydration
Comparative study of enzymes related to proline metabolism in tepary bean (Phaseolus acutifolius) and common bean (Phaseolus vulgaris) under drought and irrigated conditions, and various urea concentrations.
Dehydration
Corrigendum to: Ammonium metabolism in Selaginella bryopteris in response to dehydration-rehydration and characterisation of desiccation tolerant, thermostable, cytosolic glutamine synthetase from plant.
Dehydration
Effect of water stress on growth and proline metabolism of Phaseolus vulgaris L.
Dehydration
Nitric Oxide Signal, Nitrogen Metabolism, and Water Balance Affected by ?-Aminobutyric Acid (GABA) in Relation to Enhanced Tolerance to Water Stress in Creeping Bentgrass.
Dehydration
Nitrogen Metabolism in Adaptation of Photosynthesis to Water Stress in Rice Grown under Different Nitrogen Levels.
Dehydration
Over-expression of a glutamate dehydrogenase gene, MgGDH, from Magnaporthe grisea confers tolerance to dehydration stress in transgenic rice.
Dehydration
Ten-Step Minimally Invasive Treatment of Lumbar Giant Disc Herniation via Unilateral Tubular Laminotomy for Bilateral Decompression: 2-Dimensional Operative Video.
Dental Plaque
[Biochemical studies of glutamate dehydrogenase in fusobacterium from human dental plaque (author's transl)]
Diabetes Mellitus, Experimental
[Changes of some energy exchange parameters in the rat heart under insulin hypoglycemia]
Diabetes Mellitus, Type 2
Glutamate dehydrogenase, insulin secretion, and type 2 diabetes: a new means to protect the pancreatic ?-cell?
Diabetes, Gestational
Low mitochondrial glycerophosphate dehydrogenase activity in lymphocytes of women with gestational diabetes.
Digestive System Diseases
[Diagnostic significance of serum glutamate dehydrogenase in hepatobiliary diseases]
Drug Resistant Epilepsy
Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy.
Dysentery
[Findings concerning characteristics of responses to administration of vaccines containing antigenic complexes of enteric bacteria and tetanus toxoid]
Eczema
Bile Duct Lesions Associated With Turnip (Brassica rapa) Photosensitization Compared With Those Due to Sporidesmin Toxicosis in Dairy Cows.
Eczema
Could Nitrile Derivatives of Turnip (Brassica rapa) Glucosinolates Be Hepato- or Cholangiotoxic in Cattle?
Endocarditis
Streptococcus tigurinus is frequent among gtfR-negative Streptococcus oralis isolates and in the human oral cavity, but highly virulent strains are uncommon.
Endometriosis
A potential role of Sirtuin3 and its target enzyme activities in patients with ovarian endometrioma.
Endotoxemia
[The effect of triamcinolone acetonide on the liver mitochondria in endotoxemia]
Epilepsies, Myoclonic
Myoclonic absence epilepsy with photosensitivity and a gain of function mutation in glutamate dehydrogenase.
Epilepsies, Partial
Enzyme changes in actively spiking areas of human epileptic cerebral cortex.
Epilepsy
Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations.
Epilepsy
Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy.
Epilepsy
Expression of glutamine synthetase and glutamate dehydrogenase in the latent phase and chronic phase in the kainate model of temporal lobe epilepsy.
Epilepsy
Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations.
Epilepsy
Myoclonic absence epilepsy with photosensitivity and a gain of function mutation in glutamate dehydrogenase.
Epilepsy, Absence
Specific alteration in the expression of glial fibrillary acidic protein, glutamate dehydrogenase, and glutamine synthetase in rats with genetic absence epilepsy.
Epilepsy, Generalized
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
Epilepsy, Temporal Lobe
Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Expression of glutamine synthetase and glutamate dehydrogenase in the latent phase and chronic phase in the kainate model of temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Fascioliasis
Biochemical indicators of liver injury in calves with experimental fascioliasis.
Fascioliasis
Chronic subclinical ovine fascioliasis: plasma glutamate dehydrogenase, gamma-glutamyl transpeptidase and aspartate aminotransferase activities and their significance as diagnostic aids.
Fatty Liver
Evaluation of ornithine carbamoyl transferase and other serum and liver-derived analytes in diagnosis of fatty liver and postsurgical outcome of left-displaced abomasum in dairy cows.
Fatty Liver
Glucose and insulin responses to glucagon injection in dairy cows with ketosis and fatty liver.
Fatty Liver
Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice.
Fatty Liver
Impaired hepatic autophagic activity in dairy cows with severe fatty liver is associated with inflammation and reduced liver function.
Fatty Liver
Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in rats.
Fatty Liver, Alcoholic
Hepatic gamma-glutamyltransferase activity in alcoholic fatty liver: comparison with other liver enzymes in man and rats.
Favism
Serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, gamma-glutamyl transpeptidase and glutamic dehydrogenase levels in favism.
Fibrosarcoma
Glutamate dehydrogenase activity in subcellular fractions of mouse fibrosarcoma.
fumarate hydratase deficiency
Combined metabolomic and correlation networks analyses reveal fumarase insufficiency altered amino acid metabolism.
Gastrointestinal Diseases
Malnutrition and related risk factors in older adults from different health-care settings: an enable study.
Genetic Diseases, Inborn
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
Giardiasis
A natural zoonotic giardiasis: Infection of a child via Giardia cysts in pet chinchilla droppings.
Giardiasis
Comparison of ELISA, nested PCR and sequencing and a novel qPCR for detection of Giardia isolates from Jordan.
Giardiasis
Comparison of two target genes for detection and genotyping of Giardia lamblia in human feces by PCR and PCR-restriction fragment length polymorphism.
Giardiasis
High prevalence Giardia duodenalis assemblage B and potentially zoonotic subtypes in sporadic human cases in Western Australia.
Giardiasis
Molecular Genotyping of Giardia duodenalis Isolates from Symptomatic Individuals Attending Two Major Public Hospitals in Madrid, Spain.
Giardiasis
Multilocus genotyping and risk factor analysis of Giardia duodenalis in dogs in Korea.
Gingivitis
[Activity of glutamate dehydrogenase, gamma-glutamyltranspeptidase and creatine kinase in saliva in gingivitis]
Glioblastoma
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or akt signaling.
Glioblastoma
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness.
Glioblastoma
[Primary and secondary glioblastoma. Distinction by glutamate dehydrogenase activity]
Glioma
Characterization of glutamate dehydrogenase isoproteins purified from the cerebellum of normal subjects and patients with degenerative neurological disorders, and from human neoplastic cell lines.
Glioma
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
Glioma
Glutamate dehydrogenase (GDH) regulates bioenergetics and redox homeostasis in human glioma.
glutamate dehydrogenase deficiency
Clinical expression of glutamate dehydrogenase deficiency.
glutamate dehydrogenase deficiency
Decreased glutamate dehydrogenase protein in spinocerebellar degeneration.
glutamate dehydrogenase deficiency
Decreased viability of skin fibroblasts from patients with glutamate dehydrogenase deficiency.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase (GDH) deficiency in different types of progressive hereditary cerebellar ataxia.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase and aspartate aminotransferase in leukocytes of patients with motor neuron disease.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase and its isozyme activity in olivopontocerebellar atrophy.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in cerebellar degenerations: clinical, biochemical and molecular genetic aspects.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in Machado-Joseph disease.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in patients with olivopontocerebellar atrophy.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in spinocerebellar degenerations.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in three patients with spinocerebellar ataxia: a new enzymatic defect?
glutamate dehydrogenase deficiency
Glutamate dehydrogenase deficiency in three patients with spinocerebellar syndrome.
glutamate dehydrogenase deficiency
Glutamate dehydrogenase isoenzymes in the bovine retina and human leukocyte.
glutamate dehydrogenase deficiency
Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction.
glutamate dehydrogenase deficiency
Multiple system degeneration with glutamate dehydrogenase deficiency: pathology and biochemistry.
glutamate dehydrogenase deficiency
Neonatal hyperinsulinemic hypoglycemia. Two case reports.
glutamate dehydrogenase deficiency
Neurological disorders associated with deficiency of glutamate dehydrogenase.
glutamate dehydrogenase deficiency
Neurophysiologic study of olivopontocerebellar atrophy with or without glutamate dehydrogenase deficiency.
glutamate dehydrogenase deficiency
Pathology of olivopontocerebellar atrophy with glutamate dehydrogenase deficiency.
glutamate dehydrogenase deficiency
The natural history of hyperuricemia among asymptomatic relatives of patients with gout.
Heart Failure
The diagnostic significance of liver cell inhomogeneity: serum enzymes in patients with central liver necrosis and the distribution of glutamate dehydrogenase in normal human liver.
Hepatic Encephalopathy
Effects of acute hepatic encephalopathy and in vitro treatment with ammonia on glutamate oxidation in bulk-isolated astrocytes and mitochondria of the rat brain.
Hepatic Encephalopathy
Hyperammonemia and hepatic encephalopathy stimulate rat cerebral synaptic mitochondrial glutamate dehydrogenase activity specifically in the direction of glutamate oxidation.
Hepatic Encephalopathy
[Changes of glutamic dehydrogenase and ornithine carbamyl transferase activities in sera in patients with hepatic encephalopathy]
Hepatic Encephalopathy
[The enzymatic activity of ammonia metabolism in the liver during the parenteral nitrogen feeding of animals with experimental liver failure]
Hepatic Insufficiency
[The enzymatic activity of ammonia metabolism in the liver during the parenteral nitrogen feeding of animals with experimental liver failure]
Hepatitis
A diagnostic approach to different types of non-A non-B acute hepatitis through the evaluation of the lobular distribution of hepatocytic damage.
Hepatitis
Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic.
Hepatitis
Multivariate analysis of an enzymic profile for the differential diagnosis of viral hepatitis.
Hepatitis
T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay?
Hepatitis
[Clinical evaluation of glutamate dehydrogenase in viral hepatitis and jaundice of other origins]
Hepatitis
[Comparative studies on vitamin B 12 and glutamic dehydrogenase serum levels in children with acute viral hepatitis]
Hepatitis
[Glutamate dehydrogenase activity in the blood serum in viral hepatitis and other liver diseases]
Hepatitis
[Glutamic dehydrogenase and alcohol dehydrogenase of blood in various conditions of experimental hepatic necrosis: hepatitis due to MHV-3 virus, acute poisoning due to carbon tetrachloride.]
Hepatitis
[Research on the diagnostic value of some enzyme activities in icteric hepatitis in childhood. I. Ornithine carbamoyltransferase and glutamate dehydrogenase]
Hepatitis
[Significance of the determination of glutamate dehydrogenase (GLDH) in viral hepatitis in childhood]
Hepatitis
[Significance of the proteinogram and the determination of glutamate dehydrogenase in atypical forms of viral hepatitis]
Hepatitis, Alcoholic
Serum glutamate dehydrogenase is not a reliable marker of liver cell necrosis in alcoholics.
Hepatitis, Chronic
Hepatic activity and mRNA expression of aspartate aminotransferase isoenzymes in alcoholic and nonalcoholic liver disease.
Hepatitis, Chronic
Multivariate analysis of an enzymic profile for the differential diagnosis of viral hepatitis.
Hyperalgesia
Intraplantar injection of gangliosides produces nociceptive behavior and hyperalgesia via a glutamate signaling mechanism.
Hypercholesterolemia
The influence of fluoride ions upon selected enzymes of protein metabolism in blood plasma of rabbits with hypercholesterolemia.
Hyperglycemia
Effects of sodium nitroprusside on blood glucose concentration, B-cell morphology and islet glutamate dehydrogenase activity in mice.
Hyperglycemia
Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice.
Hyperinsulinism
A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase.
Hyperinsulinism
Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase.
Hyperinsulinism
Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism.
Hyperinsulinism
Clinical and Molecular Spectrum of Glutamate Dehydrogenase Gene Defects in 26 Chinese Congenital Hyperinsulinemia Patients.
Hyperinsulinism
Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.
Hyperinsulinism
Correction to: Hyperinsulinism associated with GLUD1 mutation: allosteric regulation and functional characterization of p.G446V glutamate dehydrogenase.
Hyperinsulinism
Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations.
Hyperinsulinism
From pancreatic islets to central nervous system, the importance of glutamate dehydrogenase for the control of energy homeostasis.
Hyperinsulinism
Functional hyperactivity of hepatic glutamate dehydrogenase as a cause of the hyperinsulinism/hyperammonemia syndrome: effect of treatment.
Hyperinsulinism
Glutamate Dehydrogenase as a Promising Target for Hyperinsulinism Hyperammonemia Syndrome Therapy.
Hyperinsulinism
Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site.
Hyperinsulinism
Hunting for a hypoglycemia gene: severe neonatal hypoglycemia in a consanguineous family.
Hyperinsulinism
Hyperinsulinaemic hypoglycaemia:genetic mechanisms, diagnosis and management.
Hyperinsulinism
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene.
Hyperinsulinism
Hyperinsulinism associated with GLUD1 mutation: allosteric regulation and functional characterization of p.G446V glutamate dehydrogenase.
Hyperinsulinism
Hyperinsulinism hyperammonaemia (HI/HA) syndrome due to GLUD1 mutation: phenotypic variations ranging from late presentation to spontaneous resolution.
Hyperinsulinism
Impaired FAD-glycerophosphate dehydrogenase activity in islet and liver homogenates of fa/fa rats.
Hyperinsulinism
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.
Hyperinsulinism
Mitochondrial GTP insensitivity contributes to hypoglycemia in Hyperinsulinemia Hyperammonemia (HI/HA) by inhibiting glucagon release.
Hyperinsulinism
Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell.
Hyperinsulinism
Monogenic hyperinsulinemic hypoglycemia: current insights into the pathogenesis and management.
Hyperinsulinism
Protein causes hyperinsulinemia: a Chinese patient with hyperinsulinism/hyperammonaemia syndrome due to a glutamate dehydrogenase gene mutation.
Hyperinsulinism
Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?
Hyperinsulinism
Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.
Hyperinsulinism
Stimulatory effects of malathion on the key enzymes activities of insulin secretion in langerhans islets, glutamate dehydrogenase and glucokinase.
Hyperinsulinism
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
Hyperinsulinism
Two unrelated Chinese patients with hyperinsulinism /hyperammonemia (HI/HA) syndrome due to mutations in glutamate dehydrogenase gene.
Hyperkalemia
Comparison of classic hypoadrenocorticism with glucocorticoid-deficient hypoadrenocorticism in dogs: 46 cases (1985-2005).
Hyperlipidemias
Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in rats.
Hyperoxaluria, Primary
Enzymological characterization of a feline analogue of primary hyperoxaluria type 2: a model for the human disease.
Hyperthyroidism
[Effect of experimental changes in thyroid function on oxidative metabolism and glutamate dehydrogenase activity in the limbic system of the rat]
Hypoglycemia
A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase.
Hypoglycemia
Biochemical evaluation of an infant with hypoglycemia resulting from a novel de novo mutation of the GLUD1 gene and hyperinsulinism-hyperammonemia syndrome.
Hypoglycemia
Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations.
Hypoglycemia
Congenital Hyperinsulinemic Hypoglycemia and Hyperammonemia due to Pathogenic Variants in GLUD1.
Hypoglycemia
Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice.
Hypoglycemia
Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor.
Hypoglycemia
Glutamate dehydrogenase: role in regulating metabolism and insulin release in pancreatic ?-cells.
Hypoglycemia
GREEN TEA POLYPHENOLS CONTROL DYSREGULATED GLUTAMATE DEHYDROGENASE IN TRANSGENIC MICE BY HIJACKING THE ADP ACTIVATION SITE.
Hypoglycemia
Hyperinsulinemic hypoglycemia: think of hyperinsulinism/hyperammonemia (HI/HA) syndrome caused by mutations in the GLUD1 gene.
Hypoglycemia
Hyperinsulinism/hyperammonemia (HI/HA) syndrome due to a mutation in the glutamate dehydrogenase gene.
Hypoglycemia
Mitochondrial GTP insensitivity contributes to hypoglycemia in Hyperinsulinemia Hyperammonemia (HI/HA) by inhibiting glucagon release.
Hypoglycemia
Myoclonic absence epilepsy with photosensitivity and a gain of function mutation in glutamate dehydrogenase.
Hypoglycemia
Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation.
Hypoglycemia
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP+ binding site.
Hypoglycemia
Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations.
Hypoglycemia
Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets.
Hypoglycemia
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
Hypoglycemia
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase.
Hypoglycemia
[Parameters of energy and nitrogen metabolism in rats under insulin-induced hypoglycemia]
Hypokinesia
[Activity of various oxidases and transaminases in the rat liver in the readaptation period after hypokinesia up to 30 days]
Hyponatremia
Comparison of classic hypoadrenocorticism with glucocorticoid-deficient hypoadrenocorticism in dogs: 46 cases (1985-2005).
Hypothyroidism
[Effect of experimental changes in thyroid function on oxidative metabolism and glutamate dehydrogenase activity in the limbic system of the rat]
Infections
A Clostridium difficile outbreak in an Italian hospital: the efficacy of the multi-disciplinary and multifaceted approach.
Infections
A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination.
Infections
Active equine parvovirus-hepatitis infection is most frequently detected in Austrian horses of advanced age.
Infections
Algorithm combining toxin immunoassay and stool culture for diagnosis of Clostridium difficile infection.
Infections
Algorithm proposal based on the C. Diff Quik Chek Complete ICT device for detecting Clostridium difficile infection.
Infections
An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells.
Infections
Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials.
Infections
Characterization of Streptococcus suis serotype 2 blood infections using RT-qPCR to quantify glutamate dehydrogenase copy numbers.
Infections
Chronic subclinical ovine fascioliasis: plasma glutamate dehydrogenase, gamma-glutamyl transpeptidase and aspartate aminotransferase activities and their significance as diagnostic aids.
Infections
Clinical significance of a positive Clostridioides difficile glutamate dehydrogenase test on the outcomes of hospitalized older patients.
Infections
Clostridioides difficile in Outpatients: Application of a Diagnostic Algorithm Recommended by the European Society of Clinical Microbiology and Infectious Diseases.
Infections
Clostridium difficile glutamate dehydrogenase is a secreted enzyme that confers resistance to H2O2.
Infections
Clostridium difficile infection diagnostics - evaluation of the C. DIFF Quik Chek Complete assay, a rapid enzyme immunoassay for detection of toxigenic C. difficile in clinical stool samples.
Infections
Combination of culture, antigen and toxin detection, and cytotoxin neutralization assay for optimal Clostridium difficile diagnostic testing.
Infections
Comprehensive evaluation of chemiluminescent immunoassays for the laboratory diagnosis of Clostridium difficile infection.
Infections
Defining the Metabolic Pathways and Host-Derived Carbon Substrates Required for Francisella tularensis Intracellular Growth.
Infections
Detection of glutamate dehydrogenase enzyme activity in Plasmodium falciparum infection.
Infections
Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A/B testing on stool samples.
Infections
Diagnostic test accuracy of glutamate dehydrogenase for Clostridium difficile: Systematic review and meta-analysis.
Infections
Efficacy of an injectable combination anthelmintic (nitroxynil+clorsulon+ivermectin) against early immature Fasciola hepatica compared to triclabendazole combination flukicides given orally or topically to cattle.
Infections
Engineering Bacillus velezensis with high production of acetoin primes strong induced systemic resistance in Arabidopsis thaliana.
Infections
Evaluation of a rapid membrane enzyme immunoassay for the simultaneous detection of glutamate dehydrogenase and toxin for the diagnosis of Clostridium difficile infection.
Infections
Evaluation of a simultaneous detection kit for the glutamate dehydrogenase antigen and toxin A/B in feces for diagnosis of Clostridium difficile infection.
Infections
Evaluation of risk factors for Clostridium difficile infection based on immunochromatography testing and toxigenic culture assay.
Infections
Evolution of Testing Algorithms at a University Hospital for Detection of Clostridium difficile Infections.
Infections
GDH and toxin immunoassay for the diagnosis of Clostridioides (Clostridium) difficile infection is not a 'one size fit all' screening test.
Infections
Giardiasis in NSW: Identification of Giardia duodenalis assemblages contributing to human and cattle cases, and an epidemiological assessment of sporadic human giardiasis.
Infections
Glutamate dehydrogenase for laboratory diagnosis of Clostridium difficile infection.
Infections
Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress.
Infections
Hepatitis E in blood donors: investigation of the natural course of asymptomatic infection, Germany, 2011.
Infections
Immunochromatographic test and ELISA for the detection of glutamate dehydrogenase (GDH) and A/B toxins as an alternative for the diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea in foals and neonatal piglets.
Infections
Infection rate and genetic diversity of Giardia duodenalis assemblage C in Iranian stray dogs, targeting the glutamate dehydrogenase gene.
Infections
Is Clostridioides difficile toxins detection necessary when the glutamate dehydrogenase enzyme is detected?
Infections
Laboratory diagnosis of clostridium difficile infection. An evaluation of tests for faecal toxin, glutamate dehydrogenase, lactoferrin and toxigenic culture in the diagnostic laboratory.
Infections
Metabolic adjustments during compatible interaction between barley genotypes and stripe rust pathogen.
Infections
Mixed Giardia duodenalis assemblage infections in children and adults in South India.
Infections
Molecular diversity and frequency of the diarrheagenic enteric protozoan Giardia duodenalis and Cryptosporidium spp. in a hospital setting in Northern Spain.
Infections
Molecular test to determine toxigenic capabilities in GDH-positive, toxin-negative samples: evaluation of the Portrait toxigenic C. difficile assay.
Infections
Occurrence and multilocus genotyping of Giardia duodenalis from post-weaned dairy calves in Sichuan province, China.
Infections
Plasma aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH) and gamma-glutamyl transpeptidase (GGT) activities in water buffaloes with experimental subclinical fasciolosis.
Infections
Prospective Evaluation of the mariPOC® Test for the Detection of Clostridioides difficile GDH and Toxins A/B.
Infections
Proteome analysis reveals translational inhibition of Caenorhabditis elegans enhances susceptibility to Pseudomonas aeruginosa PAO1 pathogenesis.
Infections
Rapid identification of Giardia duodenalis assemblages in NSW using terminal-restriction fragment length polymorphism.
Infections
Recirculation of Giardia lamblia Assemblage A After Metronidazole Treatment in an Area With Assemblages A, B, and E Sympatric Circulation.
Infections
Serum and bile antibody responses (IgG and IgA) during subclinical Fasciola hepatica infection in sheep.
Infections
Simultaneous Detection of Clostridioides difficile Glutamate Dehydrogenase and Toxin A/B: Comparison of the C. DIFF QUIK CHEK COMPLETE and RIDASCREEN Assays.
Infections
Stool antigen immunodetection for diagnosis of Giardia duodenalis infection in human subjects with HIV and cancer.
Infections
The effect of experimental fascioliasis on the pharmacokinetics of antipyrine and sulphadimidine in desert sheep.
Infections
The effects of fascioliasis on the activities of some drug-metabolizing enzymes in desert sheep liver.
Infections
The fate of glutamate in different brain regions of the chick during Newcastle disease virus infection.
Infections
The predominance and clustering of Clostridioides (Clostridium) difficile PCR ribotype 001 isolates in three hospitals in Eastern Slovakia, 2017.
Infections
The resistance of sheep to Fasciola hepatica: studies on the pathophysiology of challenge infections.
Infections
The Role of Glutamate Dehydrogenase (GDH) Testing Assay in the Diagnosis of Clostridium difficile Infections: A High Sensitive Screening Test and an Essential Step in the Proposed Laboratory Diagnosis Workflow for Developing Countries like China.
Infections
The zoonotic potential of Giardia and Cryptosporidium in Norwegian sheep: A longitudinal investigation of 6 flocks of lambs.
Infections
Trends in Healthcare Facility-Onset Clostridioides difficile Infection and the Impact of Testing Schemes in an Acute Care Hospital System in New York City, 2016-2019.
Infections
[Alteration of enzyme activities in serum of Eimeria stiedai infected rabbits (author's transl)]
Infectious Mononucleosis
Glutamate dehydrogenase activity in lymphocytes of B-cell chronic lymphocytic leukaemia patients.
Infertility, Male
Testis-Specific Bb8 Is Essential in the Development of Spermatid Mitochondria.
Inflammatory Bowel Diseases
Low glutamate dehydrogenase levels are associated with colonization in Clostridium difficile PCR-only positive patients with inflammatory bowel disease.
Insulinoma
Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism.
Insulinoma
Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation.
Insulinoma
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.
Insulinoma
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase.
Intellectual Disability
Deregulation of glutamate dehydrogenase in human neurologic disorders.
Intervertebral Disc Displacement
Ten-Step Minimally Invasive Treatment of Lumbar Giant Disc Herniation via Unilateral Tubular Laminotomy for Bilateral Decompression: 2-Dimensional Operative Video.
Intestinal Diseases
[Alanine aminotransferase (ALT), aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH), alkaline phosphatase (AP) and gamma-glutamyltransferase (GGP) in intestinal diseases of dogs]
Iron Deficiencies
The pleiotropic effects of the glutamate dehydrogenase (GDH) pathway in Saccharomyces cerevisiae.
Ketosis
Glucose and insulin responses to glucagon injection in dairy cows with ketosis and fatty liver.
Leukemia
Glutamic acid dehydrogenase and glutamic-oxalacetic transaminase of blood in leukemia and cancer.
Leukemia
[Characteristics of leukemic blood cells. V. Glutamic acid dehydrogenase in leukemias and summary.]
Leukemia, Lymphoid
Glutamate dehydrogenase activity in lymphocytes of B-cell chronic lymphocytic leukaemia patients.
Leukemia, Myeloid, Acute
High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.
Liver Cirrhosis, Alcoholic
Hepatic activity and mRNA expression of aspartate aminotransferase isoenzymes in alcoholic and nonalcoholic liver disease.
Liver Diseases
Adaptation of methods for glutamate dehydrogenase and alcohol dehydrogenase activities to a centrifugal analyser: assessment of their clinical use in anoxic states of the liver.
Liver Diseases
Field study of dairy cows with reduced appetite in early lactation: clinical examinations, blood and rumen fluid analyses.
Liver Diseases
Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-state.
Liver Diseases
Masking by enzyme inhibitor of raised serum glutamate dehydrogenase activity in Reye's syndrome.
Liver Diseases
Mitochondrial enzyme activities in liver biopsies from patients with alcoholic liver disease.
Liver Diseases
Mitochondrial enzymes in human serum: comparative determinations of glutamate dehydrogenase and mitochondrial aspartate aminotransferase in healthy persons and patients with chronic liver diseases.
Liver Diseases
Multivariate analysis of an enzymic profile for the differential diagnosis of viral hepatitis.
Liver Diseases
Nephrotoxicity and hepatotoxicity in calves apparently caused by experimental feeding with Narthecium ossifragum.
Liver Diseases
Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome.
Liver Diseases
The diagnostic significance of liver cell inhomogeneity: serum enzymes in patients with central liver necrosis and the distribution of glutamate dehydrogenase in normal human liver.
Liver Diseases
The mechanism of release of hepatic enzymes in various liver diseases. II. Altered activity ratios of GOT to GPT in serum and liver of patients with liver diseases.
Liver Diseases
The mechanism of the release of hepatic enzymes in various liver diseases. 1. Alterations in cytoplasmic and mitochondrial enzyme activities in serum.
Liver Diseases
[Activity of glutamic acid dehydrogenase in serum of patients with liver diseases]
Liver Diseases
[Glutamate dehydrogenase activity in the blood serum in viral hepatitis and other liver diseases]
Liver Diseases
[On the influence of surgery on the biliary system, especially in liver diseases, on the serum level of the enzymes sorbitol dehydrogenase, glutamic-pyruvic transaminase, lactate dehydrogenase and glutamic dehydrogenase.]
Liver Diseases, Alcoholic
Adaptation of methods for glutamate dehydrogenase and alcohol dehydrogenase activities to a centrifugal analyser: assessment of their clinical use in anoxic states of the liver.
Liver Diseases, Alcoholic
Plasma glutamate dehydrogenase: clinical application in patients with alcoholic liver disease.
Liver Diseases, Alcoholic
Serum glutamate dehydrogenase as a marker of hepatocyte necrosis in alcoholic liver disease.
Liver Diseases, Alcoholic
Serum level of ornithine carbamoyltransferase is influenced by the state of Kupffer cells.
Liver Failure
Hyperammonemia and hepatic encephalopathy stimulate rat cerebral synaptic mitochondrial glutamate dehydrogenase activity specifically in the direction of glutamate oxidation.
Liver Failure
miR?30a?5p inhibits hypoxia/reoxygenation?induced oxidative stress and apoptosis in HK?2 renal tubular epithelial cells by targeting glutamate dehydrogenase 1 (GLUD1).
Liver Neoplasms
[On the practical utility of determining in conjunction with transaminases the values of glutamate dehydrogenase in the blood of patients with cholostatic jaundice and primary or metastatic hepatic neoplasm]
Lung Neoplasms
Hypoxia promotes mitochondrial glutamine metabolism through HIF1?-GDH pathway in human lung cancer cells.
Lymphatic Metastasis
Expression and prognostic value of glutamate dehydrogenase in extrahepatic cholangiocarcinoma patients.
Lymphoma
SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.
Lymphoma, B-Cell
SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.
Machado-Joseph Disease
Glutamate and malate dehydrogenase activities in Joseph disease and olivopontocerebellar atrophy.
Malaria
Absence of alpha-ketoglutarate dehydrogenase activity and presence of CO2-fixing activity in Plasmodium falciparum grown in vitro in human erythrocytes.
Malaria
Capacitive malaria aptasensor using Plasmodium falciparum glutamate dehydrogenase as target antigen in undiluted human serum.
Malaria
Chloroquine is a potent inhibitor of glutamate dehydrogenase in liver and kidney-cortex of rabbit.
Malaria
Detection of glutamate dehydrogenase enzyme activity in Plasmodium falciparum infection.
Malaria
Development of an aptamer-based field effect transistor biosensor for quantitative detection of Plasmodium falciparum glutamate dehydrogenase in serum samples.
Malaria
Dye coupled aptamer-captured enzyme catalysed reaction for detection of pan malaria and P. falciparum species in laboratory settings and instrument-free paper based platform.
Malaria
Glutamate dehydrogenase, the marker protein of Plasmodium falciparum--cloning, expression and characterization of the malarial enzyme.
Malaria
Glutamate dehydrogenase: a novel candidate to diagnose Plasmodium falciparum through rapid diagnostic test in blood specimen from fever patients.
Malaria
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria.
Malaria
Plasmodium falciparum glutamate dehydrogenase is genetically conserved across eight malaria endemic states of India: Exploring new avenues of malaria elimination.
Malaria
Sequence conservation of Plasmodium vivax glutamate dehydrogenase among Korean isolates and its application in seroepidemiology.
Malaria
Studies on enzyme variation in the murine malaria parasites Plasmodium berghei, P. yoelii, P. vinckei and P. chabaudi by starch gel electrophoresis.
Malaria
[Preparation of a monoclonal antibodies against Plasmodium falciparum glutamate dehydrogenase and establishment of colloidal gold-immunochromatographic assay]
Malaria, Falciparum
[Preparation of a monoclonal antibodies against Plasmodium falciparum glutamate dehydrogenase and establishment of colloidal gold-immunochromatographic assay]
Malnutrition
Effects of undernutrition and protein deficiency on glutamate dehydrogenase and decarboxylase in rat brain.
Malnutrition
Expression of a bacterial aspartase gene in Aspergillus nidulans: an efficient system for selecting multicopy transformants.
Malnutrition
Malnutrition and related risk factors in older adults from different health-care settings: an enable study.
Malnutrition
Protein malnutrition potentiates the amplifying pathway of insulin secretion in adult obese mice.
Malnutrition
The Physical Functional Capacity of Frail Elderly Persons Undergoing Ambulatory Rehabilitation is Related to Their Nutritional Status.
Maple Syrup Urine Disease
Enzymatic method for branched chain alpha-ketoacid determination: application to rapid analysis of urine and plasma samples from maple syrup urine disease patients.
Metabolic Syndrome
PREVALENCE OF THE METABOLIC SYNDROME IN MODERATELY-SEVERELY OBESE SUBJECTS WITH AND WITHOUT GROWTH HORMONE DEFICIENCY.
Motor Neuron Disease
Glutamate dehydrogenase and aspartate aminotransferase in leukocytes of patients with motor neuron disease.
Motor Neuron Disease
Lymphocyte glutamate dehydrogenase activity in normal aging and neurological diseases.
Multiple Sclerosis
[Cerebral form of glutamate dehydrogenase activity in autonomic paroxysms (attacks of panic)]
Multiple System Atrophy
Characterization of glutamate dehydrogenase isoproteins purified from the cerebellum of normal subjects and patients with degenerative neurological disorders, and from human neoplastic cell lines.
Multiple System Atrophy
Glutamate dehydrogenase deficiency in cerebellar degenerations: clinical, biochemical and molecular genetic aspects.
Multiple System Atrophy
Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders.
Multiple System Atrophy
Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy.
Multiple System Atrophy
Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene.
Muscular Dystrophy, Duchenne
Safety and disease monitoring biomarkers in Duchenne muscular dystrophy: results from a Phase II trial.
Myocardial Infarction
Systemic short-term fibrinolysis with high-dose streptokinase in acute myocardial infarction: time course of biochemical parameters.
Myocardial Infarction
[Enzyme diagnosis of liver dysfunction in acute myocardial infarct and its complications]
Neoplasm Metastasis
Expression and prognostic value of glutamate dehydrogenase in extrahepatic cholangiocarcinoma patients.
Neoplasm Metastasis
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.
Neoplasm Metastasis
Value of alkaline phosphatase, 5'-nucleotidase, gamma-glutamyltransferase, and glutamate dehydrogenase activity measurements (single and combined) in serum in diagnosis of metastasis to the liver.
Neoplasm Metastasis
[Evaluation of serum glutamic dehydrogenase activity in the diagnosis and treatment of hepatocellular carcinoma and liver metastasis]
Neoplasms
Biomolecular Interaction Assays Identified Dual Inhibitors of Glutaminase and Glutamate Dehydrogenase That Disrupt Mitochondrial Function and Prevent Growth of Cancer Cells.
Neoplasms
Both-In-One Hybrid Bacteria Suppress the Tumor Metastasis and Relapse via Tandem-Amplifying Reactive Oxygen Species-Immunity Responses.
Neoplasms
Changes in enzyme pattern of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content.
Neoplasms
Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology.
Neoplasms
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
Neoplasms
Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition.
Neoplasms
Enzyme activities of six different dehydrogenases in Ehrlich ascites cells measured by flow cytometry.
Neoplasms
Expression and prognostic value of glutamate dehydrogenase in extrahepatic cholangiocarcinoma patients.
Neoplasms
Expression of glutamine metabolism-related proteins according to molecular subtype of breast cancer.
Neoplasms
Expression of metabolism-related proteins in invasive lobular carcinoma: comparison to invasive ductal carcinoma.
Neoplasms
Expression of the glutamine metabolism-related proteins glutaminase 1 and glutamate dehydrogenase in canine mammary tumours.
Neoplasms
Flow-cytometric determination of dehydrogenase activities in primary human gastrointestinal tumor cell lines.
Neoplasms
Glutamate dehydrogenase (GDH) regulates bioenergetics and redox homeostasis in human glioma.
Neoplasms
Glutamate dehydrogenase inhibits tumor growth in gastric cancer through the Notch signaling pathway.
Neoplasms
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.
Neoplasms
Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion.
Neoplasms
Glutamic acid dehydrogenase and glutamic-oxalacetic transaminase of blood in leukemia and cancer.
Neoplasms
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
Neoplasms
Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness.
Neoplasms
GREEN TEA POLYPHENOLS CONTROL DYSREGULATED GLUTAMATE DEHYDROGENASE IN TRANSGENIC MICE BY HIJACKING THE ADP ACTIVATION SITE.
Neoplasms
Hepatic mitochondrial enzyme activity and serum amino acid composition in rats treated with tumor necrosis factor.
Neoplasms
Influence of formulation parameters on gadolinium entrapment and tumor cell uptake using folate-coated nanoparticles.
Neoplasms
Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate.
Neoplasms
L-carnitine could not improve hepatic warm ischemia-reperfusion injury despite ameliorated blood flow.
Neoplasms
Mapping the Intramolecular Communications among Different Glutamate Dehydrogenase States Using Molecular Dynamics.
Neoplasms
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Neoplasms
PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence.
Neoplasms
Prominent glutamine oxidation activity in mitochondria of avian transplantable hepatoma induced by MC-29 virus.
Neoplasms
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP+ binding site.
Neoplasms
Short-term metabolic fate of L-[13N]glutamate in the Walker 256 carcinosarcoma in vivo.
Neoplasms
Silibinin protects OTA-mediated TNF-alpha release from perfused rat livers and isolated rat Kupffer cells.
Neoplasms
The pathway of glutamate oxidation in isolated mitochondria from the avian hepatomatous growth induced by MC-29 virus.
Neoplasms
Upregulation of GLS1 Isoforms KGA and GAC Facilitates Mitochondrial Metabolism and Cell Proliferation in Epstein-Barr Virus Infected Cells.
Neoplasms
Value of alkaline phosphatase, 5'-nucleotidase, gamma-glutamyltransferase, and glutamate dehydrogenase activity measurements (single and combined) in serum in diagnosis of metastasis to the liver.
Neoplasms
[Studies of glutamate dehydrogenase activity in normal tissues and in malignant tumors]
Nervous System Diseases
Characterization of glutamate dehydrogenase isoproteins purified from the cerebellum of normal subjects and patients with degenerative neurological disorders, and from human neoplastic cell lines.
Nervous System Diseases
Degenerative neurological disorders associated with deficiency of glutamate dehydrogenase.
Nervous System Diseases
Deregulation of glutamate dehydrogenase in human neurologic disorders.
Nervous System Diseases
Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth.
Nervous System Diseases
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Nervous System Diseases
Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.
Nervous System Diseases
Glutamate dehydrogenase deficiency in cerebellar degenerations: clinical, biochemical and molecular genetic aspects.
Nervous System Diseases
Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders.
Nervous System Diseases
Leukocyte glutamate dehydrogenase in patients with degenerative neurological disorders.
Nervous System Diseases
Levels of glutamic acid decarboxylase (GAD), gamma amino butyric acid transaminase (GABA-T), glutamic acid dehydrogenase (GLDH) and proteins in cerebrospinal fluid of certain neurological disorders.
Nervous System Diseases
Neurological disorders associated with deficiency of glutamate dehydrogenase.
Nervous System Diseases
Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene.
Nervous System Diseases
Using cryo-EM to map small ligands on dynamic metabolic enzymes: Studies with glutamate dehydrogenase.
Neuroblastoma
Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.
Neuroblastoma
Small-interfering-RNA-mediated silencing of human glutamate dehydrogenase induces apoptosis in neuroblastoma cells.
Neurodegenerative Diseases
Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin.
Neurodegenerative Diseases
Allosteric regulation of glutamate dehydrogenase deamination activity.
Neurodegenerative Diseases
Cellular and regional expression of glutamate dehydrogenase in the rat nervous system: non-radioactive in situ hybridization and comparative immunocytochemistry.
Neurodegenerative Diseases
Differential Levels of Glutamate Dehydrogenase 1 (GLUD1) in BALB/c and C57BL/6 Mice and the Effects of Over-Expression of Glud1 Gene on Glutamate Release in Striatum.
Neurodegenerative Diseases
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Neurodegenerative Diseases
Regional distribution of astrocytes with intense immunoreactivity for glutamate dehydrogenase in rat brain: implications for neuron-glia interactions in glutamate transmission.
Neurodegenerative Diseases
The human GLUD2 glutamate dehydrogenase and its regulation in health and disease.
Neurodegenerative Diseases
Unaltered cytochrome oxidase, glutamate dehydrogenase and glutaminase activities in platelets from patients with sporadic amyotrophic lateral sclerosis--a study of potential pathogenetic mechanisms in neurodegenerative diseases.
Non-alcoholic Fatty Liver Disease
Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice.
Obesity
Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity.
Odontogenic Cysts
Odontogenic keratocysts: a clinical and histological study with special reference to enzyme histochemistry.
Olivopontocerebellar Atrophies
Abnormal glutamate metabolism in an adult-onset degenerative neurological disorder.
Olivopontocerebellar Atrophies
Abnormal platelet glutamate dehydrogenase activity and activation in dominant and nondominant olivopontocerebellar atrophy.
Olivopontocerebellar Atrophies
Abnormalities of mitochondrial enzymes in hereditary ataxias.
Olivopontocerebellar Atrophies
Cerebellar glutamate metabolizing enzymes in spinocerebellar ataxia type I.
Olivopontocerebellar Atrophies
Degenerative neurological disorders associated with deficiency of glutamate dehydrogenase.
Olivopontocerebellar Atrophies
Glutamate and malate dehydrogenase activities in Joseph disease and olivopontocerebellar atrophy.
Olivopontocerebellar Atrophies
Glutamate dehydrogenase and its isozyme activity in olivopontocerebellar atrophy.
Olivopontocerebellar Atrophies
Glutamate dehydrogenase deficiency in patients with olivopontocerebellar atrophy.
Olivopontocerebellar Atrophies
Glutamate dehydrogenase deficiency in spinocerebellar degenerations.
Olivopontocerebellar Atrophies
Glutamate dehydrogenase in olivopontocerebellar atrophies: leukocytes, fibroblasts, and muscle mitochondria.
Olivopontocerebellar Atrophies
Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy.
Olivopontocerebellar Atrophies
Lymphocyte glutamate dehydrogenase activity in normal aging and neurological diseases.
Olivopontocerebellar Atrophies
Multiple system degeneration with glutamate dehydrogenase deficiency: pathology and biochemistry.
Olivopontocerebellar Atrophies
Neurological disorders associated with deficiency of glutamate dehydrogenase.
Olivopontocerebellar Atrophies
Neurophysiologic study of olivopontocerebellar atrophy with or without glutamate dehydrogenase deficiency.
Olivopontocerebellar Atrophies
Olivopontocerebellar atrophy with retinal degeneration. An electroretinographic and histopathologic investigation.
Olivopontocerebellar Atrophies
Oral glutamate loading in disorders with spinocerebellar and extrapyramidal involvement: effect on plasma glutamate, aspartate and taurine.
Olivopontocerebellar Atrophies
Pathology of olivopontocerebellar atrophy with glutamate dehydrogenase deficiency.
Pancreatic Neoplasms
Flow-cytometric determination of dehydrogenase activities in primary human gastrointestinal tumor cell lines.
Pancreatitis
[Glutamate dehydrogenase activity in the pancreatic tissue in acute experimental pancreatitis and under the action of sodium thiosulphate]
Paralysis
Glutamate dehydrogenase (GDH) deficiency in different types of progressive hereditary cerebellar ataxia.
Parasitic Diseases
Development of Molecular Diagnosis Using Multiplex Real-Time PCR and T4 Phage Internal Control to Simultaneously Detect Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis from Human Stool Samples.
Parasitic Diseases
Exploring alterations in hematological and biochemical parameters, enzyme activities and serum cortisol in Besnoitia besnoiti naturally infected dairy cattle.
Parasitic Diseases
Studies on ammonia-metabolizing enzymes during Plasmodium yoelii infection and pyrimethamine treatment in mice.
Parkinson Disease
Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset.
Parkinson Disease
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Parkinson Disease
Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders.
Parkinson Disease
Lymphocyte glutamate dehydrogenase activity in normal aging and neurological diseases.
Parkinson Disease
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP+ binding site.
Parkinson Disease
The human GLUD2 glutamate dehydrogenase and its regulation in health and disease.
Parkinsonian Disorders
Decreased glutamate dehydrogenase protein in spinocerebellar degeneration.
Parkinsonian Disorders
Glutamate dehydrogenase deficiency in patients with olivopontocerebellar atrophy.
Parkinsonian Disorders
Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders.
Parkinsonian Disorders
Rehabilitation outcomes of older patients at 6 months follow-up after discharged from a geriatric day hospital (GDH).
Periodontitis
[Activity of glutamate dehydrogenase, gamma-glutamyltranspeptidase and creatine kinase in saliva in gingivitis]
Peripheral Nervous System Diseases
Glutamate dehydrogenase deficiency in patients with olivopontocerebellar atrophy.
Photosensitivity Disorders
Bile Duct Lesions Associated With Turnip (Brassica rapa) Photosensitization Compared With Those Due to Sporidesmin Toxicosis in Dairy Cows.
Photosensitivity Disorders
Could Nitrile Derivatives of Turnip (Brassica rapa) Glucosinolates Be Hepato- or Cholangiotoxic in Cattle?
Prostatic Neoplasms
PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence.
Protein Deficiency
Effects of undernutrition and protein deficiency on glutamate dehydrogenase and decarboxylase in rat brain.
Pyelonephritis
[Glutamic dehydrogenase activities in renal tissue during experimental and human ehronie pyelonephritis (author's transl)]
Renal Insufficiency, Chronic
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect.
Reye Syndrome
Absence of diffusible inhibitor of glutamate dehydrogenase in the hepatocytes of Reye syndrome patients.
Reye Syndrome
Effects of peroxidized polyunsaturated fatty acids on mitochondrial function and structure: pathogenetic implications for Reye's syndrome.
Reye Syndrome
Glutamate dehydrogenase in Reye's syndrome. Evidence for the presence of an altered enzyme in serum with increased susceptibility to inhibition by GTP.
Reye Syndrome
Masking by enzyme inhibitor of raised serum glutamate dehydrogenase activity in Reye's syndrome.
Reye Syndrome
Quantitative evaluation of the extent of hepatic enzyme changes in Reye syndrome compared with normal liver or with non-Reye liver disorders: objective criteria for animal models.
Reye Syndrome
Serum glutamate dehydrogenase and ornithine carbamyl transferase in Reye's syndrome.
Sarcoidosis
Lactate, malate and glutamate dehydrogenase activity in mediastinal lymph nodes in sarcoidosis.
Sarcoma, Yoshida
Effects of glutamate dehydrogenase, choline oxidase, and glucose-6-phosphatase on 67Ga accumulation in lysosome.
Schistosomiasis
Serum isocitric dehydrogenase and glutamic dehydrogenase in schistosomiasis.
Seizures
A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase.
Seizures
Anticonvulsant drugs, brain glutamate dehydrogenase activity and oxygen consumption.
Seizures
Biochemical evaluation of an infant with hypoglycemia resulting from a novel de novo mutation of the GLUD1 gene and hyperinsulinism-hyperammonemia syndrome.
Seizures
Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations.
Seizures
Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy.
Seizures
Effect of vigabatrin on glutamate dehydrogenase in the hippocampus of seizure prone gerbils.
Seizures
Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria.
Seizures
[Metabolic investigations of epileptic seizures: the role of aminotransferases and glutamate dehydrogenase in convulsions]
Sexually Transmitted Diseases
Population genetics of Neisseria gonorrhoeae in a high-prevalence community using a hypervariable outer membrane porB and 13 slowly evolving housekeeping genes.
Spinal Cord Ischemia
Preventive effects of intrathecal methylprednisolone administration on spinal cord ischemia in rats: the role of excitatory amino acid metabolizing systems.
Spinocerebellar Ataxias
Cerebellar glutamate metabolizing enzymes in spinocerebellar ataxia type I.
Spinocerebellar Ataxias
Decreased glutamate dehydrogenase protein in spinocerebellar degeneration.
Spinocerebellar Ataxias
Glutamate Dehydrogenase as a Neuroprotective Target Against Neurodegeneration.
Spinocerebellar Ataxias
Glutamate dehydrogenase deficiency in three patients with spinocerebellar ataxia: a new enzymatic defect?
Spinocerebellar Ataxias
Glutamate dehydrogenase deficiency in three patients with spinocerebellar syndrome.
Spinocerebellar Degenerations
Decreased glutamate dehydrogenase protein in spinocerebellar degeneration.
Spinocerebellar Degenerations
Glutamate dehydrogenase deficiency in spinocerebellar degenerations.
Spinocerebellar Degenerations
Glutamate metabolism of leukocytes and skin fibroblasts in spinocerebellar degeneration with lowered glutamate dehydrogenase activity.
Spinocerebellar Degenerations
Leucocyte glutamate dehydrogenase in various hereditary ataxias.
Spinocerebellar Degenerations
Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy.
Spinocerebellar Degenerations
Normal cerebellar glutamate dehydrogenase protein in spinocerebellar degeneration.
Spinocerebellar Degenerations
Partially deficient glutamate dehydrogenase activity and attenuated oscillatory potentials in patients with spinocerebellar degeneration.
Spinocerebellar Degenerations
[Dual nature of excitatory amino acids in the vertebrate retina]
Spinocerebellar Degenerations
[Glutamate dehydrogenase and its isozyme activity in spinocerebellar degeneration]
Starvation
Asparagine metabolism and nitrogen distribution during protein degradation in sugar-starved maize root tips.
Starvation
Changes in Viability, Cell Composition, and Enzyme Levels During Starvation of Continuously Cultured (Ammonia-Limited) Selenomonas ruminantium.
Starvation
Distinctive properties and expression profiles of glutamine synthetase from a plant symbiotic fungus.
Starvation
Dynamic transcriptome analysis of root nitrate starvation and re-supply provides insights into nitrogen metabolism in pear (Pyrus bretschneideri).
Starvation
Effect of 24-hour starvation on amino acid pool composition and enzyme activities of rat brown adipose tissue.
Starvation
Effect of glucose starvation on the nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase of yeast.
Starvation
Glutamate deamination by glutamate dehydrogenase plays a central role in amino acid catabolism in plants.
Starvation
Long-term nutritional effects on the primary liver and kidney metabolism in rainbow trout. Adaptive response to starvation and a high-protein, carbohydrate-free diet on glutamate dehydrogenase and alanine aminotransferase kinetics.
Starvation
Metabolic pathways of ammoniogenesis in the shrimp Crangon crangon L.: possible role of glutamate dehydrogenase.
Starvation
Metabolic responses to short starvation and refeeding in Dicentrarchus labrax. Effect of dietary composition
Starvation
Muliple sites of action of cycloheximide in addition to inhibition of protein synthesis in Physarum polycephalum.
Starvation
Multiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological Implications.
Starvation
Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals.
Starvation
NAD(H)-dependent glutamate dehydrogenase is essential for the survival of Arabidopsis thaliana during dark-induced carbon starvation.
Starvation
New insights towards the function of glutamate dehydrogenase revealed during source-sink transition of tobacco (Nicotiana tabacum) plants grown under different nitrogen regimes.
Starvation
Physiological role and regulation of glutamate dehydrogenase in Prochlorococcus sp. strain MIT9313.
Starvation
Regulation of Saccharomyces cerevisiae nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase by proteolysis during carbon starvation.
Starvation
Screening, morphological and molecular characterization of fungi producing cystathionine ?-lyase.
Starvation
Stress-induced changes in glutamate dehydrogenase activity imply its role in adaptation to C and N metabolism in lupine embryos.
Starvation
The dynamics of local kinetic parameters of glutamate dehydrogenase in rat liver.
Starvation
The influence of high dietary protein, energy and mineral intake on deficient young camel (Camelus dromedarius)--I. Changes in metabolic profiles and growth performance.
Starvation
The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component.
Stomach Neoplasms
Flow-cytometric determination of dehydrogenase activities in primary human gastrointestinal tumor cell lines.
Stomach Neoplasms
Glutamate dehydrogenase inhibits tumor growth in gastric cancer through the Notch signaling pathway.
Striatonigral Degeneration
Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy.
Subacute Sclerosing Panencephalitis
Promoter specificity of sigma G-containing RNA polymerase from sporulating cells of Bacillus subtilis: identification of a group of forespore-specific promoters.
sulfite oxidase deficiency
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase.
Supranuclear Palsy, Progressive
Leukocyte glutamate dehydrogenase activity in patients with degenerative neurological disorders.
Tauopathies
Identification of non-Alzheimer's disease tauopathies-related proteins by proteomic analysis.
Thiamine Deficiency
Interplay Between Thiamine and p53/p21 Axes Affects Antiproliferative Action of Cisplatin in Lung Adenocarcinoma Cells by Changing Metabolism of 2-Oxoglutarate/Glutamate.
Thiamine Deficiency
Physiological studies on the effects of nutritional imbalance on the central nervous system. II. Effects of thiamine deficiency on oxidative enzymes in the brain of chicken, Gallus domesticus.
Thrombocytopenia
NTP Toxicology and Carcinogenesis Studies of Chloroprene (CAS No. 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).
Thyrotoxicosis
[Effect of experimental changes in thyroid function on oxidative metabolism and glutamate dehydrogenase activity in the limbic system of the rat]
Tuberculosis
Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress.
Tuberculosis
The gdhB gene of Pseudomonas aeruginosa encodes an arginine-inducible NAD(+)-dependent glutamate dehydrogenase which is subject to allosteric regulation.
Typhoid Fever
[Enzymatic activity in the lung cells to the intrapulmonary administration of antigen]
Typhoid Fever
[The effect of lipids from typhoid endotoxin on the activity of some liver enzymes]
Vitamin E Deficiency
Combined vitamin E deficiency and ethanol pretreatment: liver glutathione and enzyme changes.
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
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PDB
SCOP
CATH
UNIPROT
ORGANISM
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kujo, C.; Sakuraba, H.; Nunoura, N.; Ohshima, T.
The NAD-dependent glutamate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum: cloning, sequencing, and expression of the enzyme gene(1)
Biochim. Biophys. Acta
1434
365-371
1999
Pyrobaculum islandicum (Q9Y8I4), Pyrobaculum islandicum
brenda
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Release 2023.1 (January 2023)
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