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Information on EC 1.3.99.4 - 3-oxosteroid 1-dehydrogenase and Organism(s) Comamonas testosteroni and UniProt Accession Q06401

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This record set is specific for:
Comamonas testosteroni
UNIPROT: Q06401 not found.
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Word Map
The taxonomic range for the selected organisms is: Comamonas testosteroni
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
kstd2, kstd3, kstd1, ksdd3, ksdd1, steroid-1-dehydrogenase, ksdd2, delta1-dehydrogenase, 3-ketosteroid-1-en-dehydrogenase, rv3537, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1-ene-dehydrogenase
-
-
-
-
3-ketosteroid-1-en-dehydrogenase
-
-
-
-
3-ketosteroid-D1-dehydrogenase
-
-
-
-
3-ketosteroid-DELTA1-dehydrogenase
-
-
-
-
3-oxosteroid D1-dehydrogenase
-
-
-
-
3-oxosteroid Delta1-dehydrogenase
-
-
-
-
3-oxosteroid:(2,6-dichlorphenolindophenol) DELTA1-oxidoreductase
-
-
-
-
3-oxosteroid:(2,6-dichlorphenolindophenol)D1-oxidoreductase
-
-
-
-
4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase
-
-
-
-
D1-dehydrogenase
-
-
-
-
D1-steroid reductase
-
-
-
-
dehydrogenase, 3-oxo steroid Delta 1-
-
-
-
-
Delta1-dehydrogenase
-
-
-
-
DELTA1-steroid reductase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
-
-
-
-
oxidation
-
-
-
-
reduction
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
3-oxosteroid:acceptor DELTA1-oxidoreductase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9029-04-3
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
11alpha-hydroxy-testosterone + acceptor
11alpha,17beta-dihydroxyandrost-1,4-diene-3-one + reduced acceptor
show the reaction diagram
-
-
-
-
?
11beta-hydroxy-4-androstene-3,17-dione + acceptor
11beta-hydroxy-1,4-androstene-3,17-dione + reduced acceptor
show the reaction diagram
-
-
-
-
?
17alpha-hydroxy-progesterone + acceptor
1,4-pregnene-17alpha-ol-3,20-dione + reduced acceptor
show the reaction diagram
-
4-pregnene-17alpha-ol-3,20-dione
-
-
?
17alpha-methyltestosterone + acceptor
17alpha-methylandrost-1,4-diene-3-one + reduced acceptor
show the reaction diagram
-
-
-
-
?
4-androstene-3,17-dione + acceptor
1,4-androstene-3,17-dione + reduced acceptor
show the reaction diagram
-
-
-
-
ir
4-pregnene-3,20-dione + acceptor
1,4-pregnene-3,20 dione + reduced acceptor
show the reaction diagram
-
-
-
-
?
deoxycorticosterone + acceptor
1,4-pregnene-21-ol-3,20-dione + reduced acceptor
show the reaction diagram
-
4-pregnene-21-ol-3,20-dione
-
-
?
testosterone + acceptor
17beta-hydroxyandrost-1,4-diene-3-one + reduced acceptor
show the reaction diagram
-
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
enzyme works in an early step of steroid degradation
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
estrone
-
slight
o-Iodosobenzoate
-
-
p-chloromercuribenzoate
-
-
p-chloromercuriphenylsulfonate
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
associated with fine particulate structures
-
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
3O1D_COMTE
573
0
62673
Swiss-Prot
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Levy, H.R.; Talalay, P.
Bacterial oxidation of steroids. II. Studies on the enzymatic mechanism of ring A dehydrogenation
J. Biol. Chem.
234
2014-2021
1959
Comamonas testosteroni
Manually annotated by BRENDA team
Horinouchi, M.; Hayashi, T.; Yamamoto, T.; Kudo, T.
A new bacterial steroid degradation gene cluster in Comamonas testosteroni TA441 which consists of aromatic-compound degradation genes for seco-steroids and 3-ketosteroid dehydrogenase genes
Appl. Environ. Microbiol.
69
4421-4430
2003
Comamonas testosteroni (Q06401), Comamonas testosteroni TA441 (Q06401)
Manually annotated by BRENDA team