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Information on EC 1.3.8.4 - isovaleryl-CoA dehydrogenase and Organism(s) Mus musculus and UniProt Accession Q9JHI5

for references in articles please use BRENDA:EC1.3.8.4
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EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.4 isovaleryl-CoA dehydrogenase
IUBMB Comments
Contains FAD as prosthetic group. Pentanoate can act as donor.
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This record set is specific for:
Mus musculus
UNIPROT: Q9JHI5
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Word Map
The taxonomic range for the selected organisms is: Mus musculus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
isovaleryl-coa dehydrogenase, isovaleryl-coenzyme a dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
isovaleroyl-coenzyme A dehydrogenase
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isovaleryl-coenzyme A dehydrogenase
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IVD
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
3-methylbutanoyl-CoA:electron-transfer flavoprotein oxidoreductase
Contains FAD as prosthetic group. Pentanoate can act as donor.
CAS REGISTRY NUMBER
COMMENTARY hide
37274-61-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
isovaleryl-CoA + acceptor
3-methylcrotonyl-CoA + reduced acceptor
show the reaction diagram
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-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
isovaleryl-CoA + acceptor
3-methylcrotonyl-CoA + reduced acceptor
show the reaction diagram
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Uniprot
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
IVD_MOUSE
424
0
46325
Swiss-Prot
Mitochondrion (Reliability: 1)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
the gene spans approximately 17 kb and contains 12 coding exons organized identically to the human gene, amino acid sequences are 95.8 and 89.6% identical to that of the rat and human sequences, respectively
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Willard, J.M.; Reinard, T.; Mohsen, A.W.; Vockley, J.
Cloning of genomic and cDNA for mouse isovaleryl-CoA dehydrogenase (IVD) and evolutionary comparison to other known IVDs
Gene
270
253-257
2001
Mus musculus (Q9JHI5), Mus musculus
Manually annotated by BRENDA team