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Information on EC 1.3.8.2 - 4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)

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IUBMB Comments
The enzyme catalyses four successive dehydrogenations, resulting in production of 4,4'-diapolycopene. While the enzyme from Staphylococcus aureus was only shown to produce 4,4'-diaponeurosporene in vivo , it is able to catalyse the last reaction in vitro .
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Synonyms
CrtN, CrtQa, dehydrosqualene desaturase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
15-cis-4,4'-diapophytoene + 4 FAD = all-trans-4,4'-diapolycopene + 4 FADH2
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overall reaction
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15-cis-4,4'-diapophytoene + FAD = all-trans-4,4'-diapophytofluene + FADH2
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(1a)
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all-trans-4,4'-diapo-zeta-carotene + FAD = all-trans-4,4'-diaponeurosporene + FADH2
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(1c)
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all-trans-4,4'-diaponeurosporene + FAD = all-trans-4,4'-diapolycopene + FADH2
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(1d)
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all-trans-4,4'-diapophytofluene + FAD = all-trans-4,4'-diapo-zeta-carotene + FADH2
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(1b)
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PATHWAY SOURCE
PATHWAYS
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