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Information on EC 1.3.3.8 - tetrahydroberberine oxidase

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EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.8 tetrahydroberberine oxidase
IUBMB Comments
The enzyme from Berberis sp. is a flavoprotein; that from Coptis japonica is not. (R)-Tetrahydroberberines are not oxidized.
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The enzyme appears in viruses and cellular organisms
Synonyms
(S)-H4Ber oxidase, (S)-tetrahydroberberine oxidase, (S)-THB oxidase, oxidase, (S)-tetrahydroberberine, THBO, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2
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