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Information on EC 1.3.3.3 - coproporphyrinogen oxidase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9LR75

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EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.3 coproporphyrinogen oxidase
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9LR75 not found.
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
coproporphyrinogen oxidase, coproporphyrinogen iii oxidase, hem13, cpox4, copro'gen oxidase, klhem13, coprogen oxidase, oxygen-dependent coproporphyrinogen iii oxidase, sll1185, hemn1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
coproporphyrinogen III oxidase
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Coprogen oxidase
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-
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coproporphyrinogen III oxidase
coproporphyrinogenase
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-
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COX
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-
-
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CPO III oxidase
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-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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-
-
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oxidation
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-
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reduction
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-
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oxidative decarboxylation
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-
-
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SYSTEMATIC NAME
IUBMB Comments
coproporphyrinogen:oxygen oxidoreductase (decarboxylating)
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CAS REGISTRY NUMBER
COMMENTARY hide
9076-84-0
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
coproporphyrinogen III + O2 + H+
protoporphyrinogen IX + CO2 + H2O
show the reaction diagram
-
-
-
?
coproporphyrinogen-III + O2
protoporphyrinogen-IX + CO2 + H2O
show the reaction diagram
coproporphyrinogen III + O2 + 2 H+
protoporphyrinogen-IX + 2 CO2 + 2 H2O
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
coproporphyrinogen III + O2 + H+
protoporphyrinogen IX + CO2 + H2O
show the reaction diagram
-
-
-
?
coproporphyrinogen-III + O2
protoporphyrinogen-IX + CO2 + H2O
show the reaction diagram
enzyme is involved in heme and chlorophyll biosynthesis
-
-
?
coproporphyrinogen III + O2 + 2 H+
protoporphyrinogen-IX + 2 CO2 + 2 H2O
show the reaction diagram
-
-
-
-
?
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
developing seed
Manually annotated by BRENDA team
additional information
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
additional information
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
LIN2 encodes coproporphyrinogen III oxidase, CPO, a key enzyme of the tetrapyrrole biosynthesis pathway
malfunction
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plants carrying enzyme mutant alleles show defects in gametophyte development, including nonviable pollen and embryo sacs with unfused polar nuclei. Improper differentiation of the central cell leads to defects in endosperm development. Consequently, embryo development is arrested at the globular stage
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
HEM61_ARATH
386
0
43796
Swiss-Prot
Chloroplast (Reliability: 2)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
spontaneous lesion formation mutant lin2-2
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene AtCPO-1, chromosome I, DNA and amino acid sequence determination and analysis, complementation of an enzyme-deletion Saccharomyces cerevisiae hem13 mutant, expression as GFP-fusion protein in transgenic Arabidopsis thaliana plants via Agrobacterium tumefaciens tranbsformation
gene AtCPO-2, DNA sequence determination and analysis, no complementation of an enzyme-deletion Saccharomyces cerevisiae hem13 mutant, possibly a pseudogene
gene LIN2, construction of transgenic plants expressing the mutant LIN2 gene using Agrobacterium tumefaciens strain GV3101 transfection
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Santana, M.A.; Tan, F.C.; Smith, A.G.
Molecular characterization of coproporphyrinogen oxidase from Glycine max and Arabidopsis thaliana
Plant Physiol. Biochem.
40
289-298
2002
Glycine max, Lotus japonicus, Vigna radiata var. radiata, Arabidopsis thaliana (Q93Z96), Arabidopsis thaliana (Q9LR75)
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Manually annotated by BRENDA team
Guo, C.Y.; Wu, G.H.; Xing, J.; Li, W.Q.; Tang, D.Z.; Cui, B.M.
A mutation in a coproporphyrinogen III oxidase gene confers growth inhibition, enhanced powdery mildew resistance and powdery mildew-induced cell death in Arabidopsis
Plant Cell Rep.
32
687-702
2013
Arabidopsis thaliana (Q9LR75), Arabidopsis thaliana Col-0 (Q9LR75)
Manually annotated by BRENDA team
Pratibha, P.; Singh, S.K.; Srinivasan, R.; Bhat, S.R.; Sreenivasulu, Y.
Gametophyte development needs mitochondrial coproporphyrinogen III oxidase function
Plant Physiol.
174
258-275
2017
Arabidopsis thaliana
Manually annotated by BRENDA team