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Information on EC 1.3.1.86 - crotonyl-CoA reductase

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EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.86 crotonyl-CoA reductase
IUBMB Comments
Catalyses the reaction in the reverse direction. This enzyme from Streptomyces collinus is specific for (E)-but-2-enoyl-CoA, and is proposed to provide butanoyl-CoA as a starter unit for straight-chain fatty acid biosynthesis.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
3-hydroxyacyl CoA reductase, acyl-CoA:NADP+ trans-2-oxidoreductase, bcd2, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, butyryl coenzyme A dehydrogenase, butyryl dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, CCR, CD1054, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
butanoyl-CoA + NADP+ = (E)-but-2-enoyl-CoA + NADPH + H+
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