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Information on EC 1.3.1.83 - geranylgeranyl diphosphate reductase and Organism(s) Haloferax volcanii and UniProt Accession D4GSC3

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IUBMB Comments
This enzyme also acts on geranylgeranyl-chlorophyll a. The reaction occurs in three steps. Which order the three double bonds are reduced is not known.
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Haloferax volcanii
UNIPROT: D4GSC3
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
geranylgeranyl reductase, chl p, ct2256, ppchl p, geranylgeranyl diphosphate reductase, nadph-dependent geranylgeranyl reductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
geranylgeranyl reductase
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SYSTEMATIC NAME
IUBMB Comments
geranylgeranyl-diphosphate:NADP+ oxidoreductase
This enzyme also acts on geranylgeranyl-chlorophyll a. The reaction occurs in three steps. Which order the three double bonds are reduced is not known.
CAS REGISTRY NUMBER
COMMENTARY hide
86922-67-0
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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mass spectrometry reveals that cells deleted of HVO_1799 fail to fully reduce the isoprene chains of Hfx. volcanii membrane phospholipids and glycolipids. Likewise, the absence of HVO_1799 leads to a loss of saturation of the omega-position isoprene subunit of C55 and C60 dolichol phosphate, with the effect of HVO_1799 deletion being more pronounced with C60 dolichol phosphate than with C55 dolichol phosphate