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Information on EC 1.3.1.51 - 2'-hydroxydaidzein reductase

for references in articles please use BRENDA:EC1.3.1.51

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IUBMB Comments

In the reverse reaction, the 2'-hydroxyisoflavone (2'-hydroxydaidzein) is reduced to an isoflavanone. Also acts on 2'-hydroxyformononetin and to a small extent on 2'-hydroxygenistein. Involved in the biosynthesis of the phytoalexin glyceollin. The isoflavones biochanin A, daidzein and genestein as well as the flavonoids apigenin, kaempferol and quercetin do not act as substrates.

The expected taxonomic range for this enzyme is: Glycine max

Synonyms
nadph:2'-hydroxydaidzein oxidoreductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2'-hydroxy-2,3-dihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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